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The map label for this gene is 124022540

Identifier: 124022540

GI number: 124022540

Start: 756821

End: 757393

Strand: Direct

Name: 124022540

Synonym: P9303_08311

Alternate gene names: NA

Gene position: 756821-757393 (Clockwise)

Preceding gene: 124022539

Following gene: 124022547

Centisome position: 28.21

GC content: 46.77

Gene sequence:

>573_bases
ATGCCTTCCCTTCAAAGCGTTCCAGATGTCACCTTCAAGACTCGCGTGCGCGATGAATCTGTGCCCGGGCCTAATCCATT
CCGCTGGCAAGACCTGACTAGTGCTGAAATCTTTAAGGGGCGCAAGGTGGTGGTGTTAGCCCTACCAGGTGCTTTTACGC
CTACGTGCTCATCCAATCATTTGCCACGTTATGAGGAGTTGCATACAGAACTTGTTGCCCAAGGTGTTGATCAGATTATC
TGTCTTTCAGTGAATGATGCTTTTGTAATGTTCCAGTGGCGCAAACATTTGGGCACTAAGAATATCTTTATGCTCCCTGA
TGGAAATGGAGAGTTCACTCGTAAAATGGGCATGCTTGTTGAGAAATCCAACCTAGGCTTTGGTTTGCGTTCCTGGCGCT
ATTCGATGCTAGTGAATGATTGTAATATTGAAAAAATGTTTGTTGAGCCTGGCTTTAGTGATAATGCTGATGTTGACCCG
TTTGAGGTCTCTGATGCCGATACGATGCTCGCTTACATGAAGGGTGTGCAACCAGCTGGTGTTAGTTCACCGCGCCGTAA
GTTTGAGGGTTAA

Upstream 100 bases:

>100_bases
GATCGATTCACGCCGTCGGCGATAGGTTTCAACAATTTGATCATTTGACAAGATCAGATGAGGTGTATGAGATTTTGTTT
GCATCAACATCAGCCTTTCA

Downstream 100 bases:

>100_bases
AACCTTCACTTCTCACACTCTTGCCTGTTTATTACATATAAAATTGATTATCTGTTTTCCTACTCCCCTCTATATCTTAC
ATAACAAGTAGCAATCCTCT

Product: peroxiredoxin

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPSLQSVPDVTFKTRVRDESVPGPNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHTELVAQGVDQII
CLSVNDAFVMFQWRKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADVDP
FEVSDADTMLAYMKGVQPAGVSSPRRKFEG

Sequences:

>Translated_190_residues
MPSLQSVPDVTFKTRVRDESVPGPNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHTELVAQGVDQII
CLSVNDAFVMFQWRKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADVDP
FEVSDADTMLAYMKGVQPAGVSSPRRKFEG
>Mature_189_residues
PSLQSVPDVTFKTRVRDESVPGPNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNHLPRYEELHTELVAQGVDQIIC
LSVNDAFVMFQWRKHLGTKNIFMLPDGNGEFTRKMGMLVEKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADVDPF
EVSDADTMLAYMKGVQPAGVSSPRRKFEG

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=119, Percent_Identity=43.6974789915966, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI78706776, Length=153, Percent_Identity=35.9477124183007, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI78709078, Length=153, Percent_Identity=35.9477124183007, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21356; Mature: 21225

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLQSVPDVTFKTRVRDESVPGPNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNH
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCC
LPRYEELHTELVAQGVDQIICLSVNDAFVMFQWRKHLGTKNIFMLPDGNGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHEE
EKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADVDPFEVSDADTMLAYMKGVQPAG
EECCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHHCCCCCC
VSSPRRKFEG
CCCCHHHCCC
>Mature Secondary Structure 
PSLQSVPDVTFKTRVRDESVPGPNPFRWQDLTSAEIFKGRKVVVLALPGAFTPTCSSNH
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCCCCCCCCC
LPRYEELHTELVAQGVDQIICLSVNDAFVMFQWRKHLGTKNIFMLPDGNGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHEE
EKSNLGFGLRSWRYSMLVNDCNIEKMFVEPGFSDNADVDPFEVSDADTMLAYMKGVQPAG
EECCCCCCHHHEEEEEEEECCCCEEEEECCCCCCCCCCCCEECCCHHHHHHHHHCCCCCC
VSSPRRKFEG
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]