Click here to switch to the map view.

The map label for this gene is tal [H]

Identifier: 124022466

GI number: 124022466

Start: 697537

End: 698709

Strand: Direct

Name: tal [H]

Synonym: P9303_07571

Alternate gene names: 124022466

Gene position: 697537-698709 (Clockwise)

Preceding gene: 124022465

Following gene: 124022467

Centisome position: 26.0

GC content: 47.57

Gene sequence:

>1173_bases
ATGGCCACACTCCTTGAGCAGCTTTCCACCATGACCGTGGTCGTGGCGGATACCGGTGATTTGGACGCCATTAGAAAGTT
CACCCCCAGGGATGCAACGACCAACCCTTCATTGATCCTTGCGGCGGCGCAGATTCCTGCTTATCAGAGTTTGATCGATG
AGGCTCTTCATTCCTCCCGTCAGTTATTGGGCAGCTCTGCAGCTGTGGAGGAGGTGGTCCATGAGGCTCTCGATGAAATT
TGTGTAATCTTTGGAAAGGAAATCCTCAAGATTGTTCCTGGCCGTGTTTCCACTGAAGTGGATGCTCGCCTCAGTTTCAA
TACTGAAGCCACAATCGCTAAGGCTCACAAACTCATTGGCCTATATAACGACGCTGGCATTACTAATGATCGCGTTTTGA
TCAAGATAGCTTCTACTTGGGAGGGTATAAAAGCGGCTGAGGTTTTGGAGAAAGATGGAATTCATTGCAACTTAACTCTG
CTATTTGGCTTTTCTCAGGCTGTCGCTTGTGCAGAAGCAGGAGTCACTTTGATCTCTCCTTTTGTTGGGCGAATCCTTGA
TTGGTACAAGGCTTCTACTGGTCGGGATTCTTATACAGGTCCAGAAGATCCTGGTGTGATCTCGGTGACCAAGATCTTTA
ATTACTTCAAAACCTATGATTACAAGACTGAGATCATGGGCGCGAGTTTCCGCAATCTTGACGAAATTATTGAATTGGCT
GGATGTGATTTGTTGACCATCTCACCAAAGCTTTTGGATCAGCTGCGTAGTACAGAGGCTCCGCTGATGCGTAAGTTGGA
TGCTGTCAATCCTGTTGCTGCAGAGTCTCAGATCCATGTCGATAAGGAGAGTTTTGAGTCAATGATGAGGGCTGATCGCA
TGGCTTTTGAGAAGTTGGATGAAGGGATTCGCGGCTTTAGCAAGGCGATTGAAACTCTTGAGGCTCAGTTGGCGCATCGA
TTAGCTGTTTTGGAGGGAGGAGCGGCTTTCTGCCATGTTGTTCAGGAGATTTTCATGCTCAATGATCTCGATGGTGATGG
TTGTATTACTAGAGAAGAATGGCTCGGTAGTGATGCGGTATTTGACGCCTTAGATCATGACCATGATGGCCGACTTCTTC
AGGAAGATGTTCGTTCTGGGCTGGGTGCTGCGTTGGCACTAACAACAGCTTAA

Upstream 100 bases:

>100_bases
AAGGCTAAGTCTTGGCAAAGCTTCGATGGTGAGTTCTGAACCTGGGCTGTCAGCAAAAAAAACGCCGCTAGCTTAAAGAT
CTTGCGAGACGTTCTGCTTT

Downstream 100 bases:

>100_bases
AGTCTCGCTGAATAAGGGAATGAGTCTTTCCGTTATCAATGCTTTCCCATGGCAGTAATTAGCTAAAAGACATAGAACGT
TTGGTCTTATTGAAGTCTCT

Product: transaldolase/EF-hand domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGSSAAVEEVVHEALDEI
CVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTL
LFGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYTGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
GCDLLTISPKLLDQLRSTEAPLMRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHR
LAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA

Sequences:

>Translated_390_residues
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGSSAAVEEVVHEALDEI
CVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTL
LFGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYTGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
GCDLLTISPKLLDQLRSTEAPLMRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHR
LAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA
>Mature_389_residues
ATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSRQLLGSSAAVEEVVHEALDEIC
VIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIGLYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLL
FGFSQAVACAEAGVTLISPFVGRILDWYKASTGRDSYTGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELAG
CDLLTISPKLLDQLRSTEAPLMRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLDEGIRGFSKAIETLEAQLAHRL
AVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAVFDALDHDHDGRLLQEDVRSGLGAALALTTA

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway [H]

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 EF-hand domains [H]

Homologues:

Organism=Homo sapiens, GI5803187, Length=329, Percent_Identity=57.7507598784195, Blast_Score=372, Evalue=1e-103,
Organism=Escherichia coli, GI1786189, Length=321, Percent_Identity=56.6978193146417, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1788807, Length=317, Percent_Identity=52.0504731861199, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI25153750, Length=315, Percent_Identity=56.5079365079365, Blast_Score=354, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI25153752, Length=159, Percent_Identity=55.9748427672956, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17570473, Length=91, Percent_Identity=47.2527472527472, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323386, Length=317, Percent_Identity=61.5141955835962, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6321480, Length=316, Percent_Identity=54.746835443038, Blast_Score=324, Evalue=1e-89,
Organism=Drosophila melanogaster, GI45549185, Length=316, Percent_Identity=55.0632911392405, Blast_Score=351, Evalue=4e-97,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011992
- InterPro:   IPR018247
- InterPro:   IPR018249
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225 [H]

Pfam domain/function: PF00923 Transaldolase [H]

EC number: =2.2.1.2 [H]

Molecular weight: Translated: 42464; Mature: 42333

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00018 EF_HAND_1 ; PS50222 EF_HAND_2 ; PS01054 TRANSALDOLASE_1 ; PS00958 TRANSALDOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSR
CCHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHH
QLLGSSAAVEEVVHEALDEICVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHE
LYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLLFGFSQAVACAEAGVTLISP
EECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHCCHHHHHH
FVGRILDWYKASTGRDSYTGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHCCCHHCCHHHHHHHH
GCDLLTISPKLLDQLRSTEAPLMRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLD
CCCEEEECHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
EGIRGFSKAIETLEAQLAHRLAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
FDALDHDHDGRLLQEDVRSGLGAALALTTA
HHHHCCCCCCCHHHHHHHCCCCCCEEEECC
>Mature Secondary Structure 
ATLLEQLSTMTVVVADTGDLDAIRKFTPRDATTNPSLILAAAQIPAYQSLIDEALHSSR
CHHHHHHHHEEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHH
QLLGSSAAVEEVVHEALDEICVIFGKEILKIVPGRVSTEVDARLSFNTEATIAKAHKLIG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHE
LYNDAGITNDRVLIKIASTWEGIKAAEVLEKDGIHCNLTLLFGFSQAVACAEAGVTLISP
EECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEEEECHHHHHHHHHCCHHHHHH
FVGRILDWYKASTGRDSYTGPEDPGVISVTKIFNYFKTYDYKTEIMGASFRNLDEIIELA
HHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCHHHHCCCHHCCHHHHHHHH
GCDLLTISPKLLDQLRSTEAPLMRKLDAVNPVAAESQIHVDKESFESMMRADRMAFEKLD
CCCEEEECHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHH
EGIRGFSKAIETLEAQLAHRLAVLEGGAAFCHVVQEIFMLNDLDGDGCITREEWLGSDAV
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHH
FDALDHDHDGRLLQEDVRSGLGAALALTTA
HHHHCCCCCCCHHHHHHHCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]