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The map label for this gene is phhB

Identifier: 124022422

GI number: 124022422

Start: 662114

End: 662404

Strand: Reverse

Name: phhB

Synonym: P9303_07131

Alternate gene names: NA

Gene position: 662404-662114 (Counterclockwise)

Preceding gene: 124022423

Following gene: 124022421

Centisome position: 24.69

GC content: 54.98

Gene sequence:

>291_bases
ATGACGGCAACCCTGCTTACTGCTGAACAGCTCTCTTCCGTAGCTGAAAAGCTGCCGGGGTGGACCCTGGCGGATCAACG
GCTGCGACGGCAATGGCGCTTTCGCAACTTTGTGGAAGCCTTCGGTTTTATGACCCGTGTGGCACTGCTAGCTGAAGCCA
TGAACCATCACCCGGAATGGAGCAACGTCTATGCCACTGTGACGATCGAGTTGACGACCCATGACGTCAACGGATTGAGC
GATCGTGATTTGAAGCTCGCCGAAGCAATCAATTTGCTGGAACCGGGCTAA

Upstream 100 bases:

>100_bases
GGACAACATCAAATCACCCTTCAGCCATTGCATCATTAGAGCAACACAACACAGCAACCATCACAGACAAGAATGACTCC
AAATCTCACAACACAACCTC

Downstream 100 bases:

>100_bases
TCAAAACTCACTCAGCCAAAACTGCTGCCAGCATGGAATCAACGAGCGGCTGTGGTTCCAGCACCCTCCCGCTCCCCTGA
CGGCAAGCCCATGAACGACG

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MTATLLTAEQLSSVAEKLPGWTLADQRLRRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLS
DRDLKLAEAINLLEPG

Sequences:

>Translated_96_residues
MTATLLTAEQLSSVAEKLPGWTLADQRLRRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLS
DRDLKLAEAINLLEPG
>Mature_95_residues
TATLLTAEQLSSVAEKLPGWTLADQRLRRQWRFRNFVEAFGFMTRVALLAEAMNHHPEWSNVYATVTIELTTHDVNGLSD
RDLKLAEAINLLEPG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=76, Percent_Identity=52.6315789473684, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI4557831, Length=92, Percent_Identity=47.8260869565217, Blast_Score=82, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115533705, Length=84, Percent_Identity=54.7619047619048, Blast_Score=93, Evalue=2e-20,
Organism=Drosophila melanogaster, GI45549100, Length=80, Percent_Identity=51.25, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_PROM3 (A2C7K4)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016729.1
- ProteinModelPortal:   A2C7K4
- SMR:   A2C7K4
- STRING:   A2C7K4
- GeneID:   4776512
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_07131
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   IALICEK
- ProtClustDB:   PRK00823
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 10897; Mature: 10765

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATLLTAEQLSSVAEKLPGWTLADQRLRRQWRFRNFVEAFGFMTRVALLAEAMNHHPEW
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNVYATVTIELTTHDVNGLSDRDLKLAEAINLLEPG
CCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TATLLTAEQLSSVAEKLPGWTLADQRLRRQWRFRNFVEAFGFMTRVALLAEAMNHHPEW
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SNVYATVTIELTTHDVNGLSDRDLKLAEAINLLEPG
CCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA