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The map label for this gene is yciC [H]

Identifier: 124022421

GI number: 124022421

Start: 660923

End: 662023

Strand: Reverse

Name: yciC [H]

Synonym: P9303_07121

Alternate gene names: 124022421

Gene position: 662023-660923 (Counterclockwise)

Preceding gene: 124022422

Following gene: 124022420

Centisome position: 24.68

GC content: 52.86

Gene sequence:

>1101_bases
ATGAACGACGCAATCGCATCCGAAGCAACCACTCAACCTGATCATGGCGAAGCGCCCGAGCAAGACCGGTGCGTACCGGT
AACAATCCTCACTGGCTTCCTAGGCGCCGGCAAAACCACCCTGCTCAACCACATCCTCAGCAAGCAGAAGAGCCTAAAAA
CCGCCGTATTGGTGAATGAATTCGGTGAGATTGGAATCGACAACGAGTTGATCGTCAGCACCAGCGAGGACATGGTTGAA
CTCAGCAATGGCTGCATATGCTGCTCGATCAATGGGGAGCTGCTCGAAGCGGTTGATCGGATTCTCGAACGTCCAGACCC
AATCGATTACCTCGTTGTGGAAACCACAGGCCTGGCAGATCCGCTCCCCGTTGCCATGACCTTTCTTGGCAGTGAACTGC
GAGATCAAACCCGCTTGGATTCGATCATTACCTTGATCGACGCGGAAAACTTTAACGACCAACTCTTGGAAAGCGAAGTC
GGCAGAGCCCAGGTGATCTATGGCGACATCCTGCTGCTCAACAAAACAGATCTCGTCCCTGAAGAGCGATTAAAAGAGGT
TGAATCCAAGTTGGCAGACCTCAAACAAAATCCCCGCATCCTTCGATCAATCAAAGGAGATGTGCCCTTACCGCTGCTAC
TAAGCGTGGGCCTGTTTGAAACCGATCGCGTACAACCAGCAGACGTTGCAGAGAGCCACGATCACAGTCATCACAGTCAT
CACCACGACGACGATCACAGTCATCACCACGACGATCACAGTCATCACCACGATGACAACCCTGATCACCTAGCAATCGA
AGGCTTCACATCCCTATCCTTCAGCAGCGATGACCCTTTTGCGCTGCGGAAGTTCCAAAATTTCTTAGACAATCAACTTC
CTGCAGAAGTCTTTCGTGCCAAAGGGATTCTCTGGTTCAACGAGAGCGAACGCCGCCACATCTTTCATTTAGCCGGCAAG
CGCTTCTCCATTGATGACAGCGACTGGCCCGCTGAGCGCAAGAACCAACTGGTGTTGATTGGACGCCAACTCGATCACGA
CACCCTGCGGCGCCAACTTCAGGCCTGCGTAGCAAAGGACGCCGGCAAAGGGTTCAGCTGA

Upstream 100 bases:

>100_bases
ACCGGGCTAATCAAAACTCACTCAGCCAAAACTGCTGCCAGCATGGAATCAACGAGCGGCTGTGGTTCCAGCACCCTCCC
GCTCCCCTGACGGCAAGCCC

Downstream 100 bases:

>100_bases
ATCCAACCAACAGGCAAACAGATCGACAACTTCGCCCACTGCTTGCTACTCAACAGCTGCAGCAATGGCAGTTGCTCAAC
CCGCGCCAGGAGGAGAACCT

Product: G3E family GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MNDAIASEATTQPDHGEAPEQDRCVPVTILTGFLGAGKTTLLNHILSKQKSLKTAVLVNEFGEIGIDNELIVSTSEDMVE
LSNGCICCSINGELLEAVDRILERPDPIDYLVVETTGLADPLPVAMTFLGSELRDQTRLDSIITLIDAENFNDQLLESEV
GRAQVIYGDILLLNKTDLVPEERLKEVESKLADLKQNPRILRSIKGDVPLPLLLSVGLFETDRVQPADVAESHDHSHHSH
HHDDDHSHHHDDHSHHHDDNPDHLAIEGFTSLSFSSDDPFALRKFQNFLDNQLPAEVFRAKGILWFNESERRHIFHLAGK
RFSIDDSDWPAERKNQLVLIGRQLDHDTLRRQLQACVAKDAGKGFS

Sequences:

>Translated_366_residues
MNDAIASEATTQPDHGEAPEQDRCVPVTILTGFLGAGKTTLLNHILSKQKSLKTAVLVNEFGEIGIDNELIVSTSEDMVE
LSNGCICCSINGELLEAVDRILERPDPIDYLVVETTGLADPLPVAMTFLGSELRDQTRLDSIITLIDAENFNDQLLESEV
GRAQVIYGDILLLNKTDLVPEERLKEVESKLADLKQNPRILRSIKGDVPLPLLLSVGLFETDRVQPADVAESHDHSHHSH
HHDDDHSHHHDDHSHHHDDNPDHLAIEGFTSLSFSSDDPFALRKFQNFLDNQLPAEVFRAKGILWFNESERRHIFHLAGK
RFSIDDSDWPAERKNQLVLIGRQLDHDTLRRQLQACVAKDAGKGFS
>Mature_366_residues
MNDAIASEATTQPDHGEAPEQDRCVPVTILTGFLGAGKTTLLNHILSKQKSLKTAVLVNEFGEIGIDNELIVSTSEDMVE
LSNGCICCSINGELLEAVDRILERPDPIDYLVVETTGLADPLPVAMTFLGSELRDQTRLDSIITLIDAENFNDQLLESEV
GRAQVIYGDILLLNKTDLVPEERLKEVESKLADLKQNPRILRSIKGDVPLPLLLSVGLFETDRVQPADVAESHDHSHHSH
HHDDDHSHHHDDHSHHHDDNPDHLAIEGFTSLSFSSDDPFALRKFQNFLDNQLPAEVFRAKGILWFNESERRHIFHLAGK
RFSIDDSDWPAERKNQLVLIGRQLDHDTLRRQLQACVAKDAGKGFS

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=378, Percent_Identity=31.4814814814815, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI33469141, Length=378, Percent_Identity=31.4814814814815, Blast_Score=161, Evalue=7e-40,
Organism=Homo sapiens, GI148727351, Length=378, Percent_Identity=31.4814814814815, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI223941779, Length=378, Percent_Identity=31.4814814814815, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI146231952, Length=378, Percent_Identity=31.7460317460317, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI223941776, Length=365, Percent_Identity=30.958904109589, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI119120938, Length=146, Percent_Identity=43.1506849315069, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI87082430, Length=337, Percent_Identity=33.2344213649852, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788499, Length=212, Percent_Identity=30.6603773584906, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=274, Percent_Identity=29.5620437956204, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 40943; Mature: 40943

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAIASEATTQPDHGEAPEQDRCVPVTILTGFLGAGKTTLLNHILSKQKSLKTAVLVNE
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGEIGIDNELIVSTSEDMVELSNGCICCSINGELLEAVDRILERPDPIDYLVVETTGLAD
HHCCCCCCCEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCC
PLPVAMTFLGSELRDQTRLDSIITLIDAENFNDQLLESEVGRAQVIYGDILLLNKTDLVP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEEEEECCCCCCH
EERLKEVESKLADLKQNPRILRSIKGDVPLPLLLSVGLFETDRVQPADVAESHDHSHHSH
HHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCC
HHDDDHSHHHDDHSHHHDDNPDHLAIEGFTSLSFSSDDPFALRKFQNFLDNQLPAEVFRA
CCCCCCCCCCCCCCCCCCCCCCEEEEECEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
KGILWFNESERRHIFHLAGKRFSIDDSDWPAERKNQLVLIGRQLDHDTLRRQLQACVAKD
CCEEEECCCCCCEEEEECCCEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
AGKGFS
CCCCCC
>Mature Secondary Structure
MNDAIASEATTQPDHGEAPEQDRCVPVTILTGFLGAGKTTLLNHILSKQKSLKTAVLVNE
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FGEIGIDNELIVSTSEDMVELSNGCICCSINGELLEAVDRILERPDPIDYLVVETTGLAD
HHCCCCCCCEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEECCCCC
PLPVAMTFLGSELRDQTRLDSIITLIDAENFNDQLLESEVGRAQVIYGDILLLNKTDLVP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEEEEEECCCCCCH
EERLKEVESKLADLKQNPRILRSIKGDVPLPLLLSVGLFETDRVQPADVAESHDHSHHSH
HHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCC
HHDDDHSHHHDDHSHHHDDNPDHLAIEGFTSLSFSSDDPFALRKFQNFLDNQLPAEVFRA
CCCCCCCCCCCCCCCCCCCCCCEEEEECEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHH
KGILWFNESERRHIFHLAGKRFSIDDSDWPAERKNQLVLIGRQLDHDTLRRQLQACVAKD
CCEEEECCCCCCEEEEECCCEECCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHC
AGKGFS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]