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The map label for this gene is degU [H]

Identifier: 124022269

GI number: 124022269

Start: 540790

End: 541515

Strand: Reverse

Name: degU [H]

Synonym: P9303_05591

Alternate gene names: 124022269

Gene position: 541515-540790 (Counterclockwise)

Preceding gene: 124022273

Following gene: 124022268

Centisome position: 20.19

GC content: 54.41

Gene sequence:

>726_bases
GTGGACATCACTCCCCGGATCTCTTCTCTCCAGAAAACAAGTCAACAAAGCCATCCCCTACTCCGTCGCAGTCGCACTGT
TGTCGCCACCGCCGATCGCGTCTTAATCACCAGTTGGGTGGGCTGGTTTGATTGTCTGGGTCCCCTAGTGGGCGCTGCAA
CCGGTGAGGACGAGACCCTCAGTTGCCTGAAGAGCTCTAATGCAGATCTCCTGATCTGCACCGATCTACTGGAGAGCGGG
AATGGCCCAAGCCTGGTCCGTAAAGCAAAACAGCTCAAGCCTGATCTCAAGGCCCTGATGCTGATTCAACGACCTGTATT
ACGCACCCTGCTGGATGCAATCGAAGCCCATTGCGATGGCCTCTGTGCCCATGAGCTCGTCGGCAGTGGCACCCTGTTGG
CAGCTCTTAGCGCAATCGAAAGCGATGGAACCTACTTAGACAGTGTTGTTGCAGGAGTTTTACGTCACGGTCGTCTCGGC
AATGGCAAGACCAGCAGCCAAATCGACAACCTCAGCTTGCGCGAGGGAGATGTGCTTCGAGGAATCTGTAAAGGGATGAG
CAATCAGAACATTGCCGATGAGCTCTATCTCTCGATCGATACGGTCAAGAGCCATGTGCACAACCTGCTGCAAAAATTGC
CAGCACGAGATCGCACCCATGCTGTGGTGGTGGCTTTTCGTGATGGGCTGGTGGAGTTACCTCAAAGACTGCCACGTTGG
CAATAA

Upstream 100 bases:

>100_bases
TTGGTTGGAATTGTGCAAAATTCTCGCCGTCATAAACAGTGCGGATCAACGTAATCTCCACAATGAAGCTCTAACCGCTC
CTGTTACCTGGTTGCAACCA

Downstream 100 bases:

>100_bases
CGCTGCCTTCACTGACTCGGTAACGTCCGCCTGAATGAGCGATCCCCAAAGGGTGATTGGCATCTTGCACTTTGAGCCAA
CAAGCGCAGCTCCAAAGCTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MDITPRISSLQKTSQQSHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESG
NGPSLVRKAKQLKPDLKALMLIQRPVLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLG
NGKTSSQIDNLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRW
Q

Sequences:

>Translated_241_residues
MDITPRISSLQKTSQQSHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESG
NGPSLVRKAKQLKPDLKALMLIQRPVLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLG
NGKTSSQIDNLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRW
Q
>Mature_241_residues
MDITPRISSLQKTSQQSHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETLSCLKSSNADLLICTDLLESG
NGPSLVRKAKQLKPDLKALMLIQRPVLRTLLDAIEAHCDGLCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLG
NGKTSSQIDNLSLREGDVLRGICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRW
Q

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26172; Mature: 26172

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITPRISSLQKTSQQSHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETL
CCCCCHHHHHHHHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
SCLKSSNADLLICTDLLESGNGPSLVRKAKQLKPDLKALMLIQRPVLRTLLDAIEAHCDG
HHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKTSSQIDNLSLREGDVLR
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHH
GICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRW
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHHHHCCCC
Q
C
>Mature Secondary Structure
MDITPRISSLQKTSQQSHPLLRRSRTVVATADRVLITSWVGWFDCLGPLVGAATGEDETL
CCCCCHHHHHHHHHHHCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
SCLKSSNADLLICTDLLESGNGPSLVRKAKQLKPDLKALMLIQRPVLRTLLDAIEAHCDG
HHHHCCCCCEEEEHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LCAHELVGSGTLLAALSAIESDGTYLDSVVAGVLRHGRLGNGKTSSQIDNLSLREGDVLR
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCHHHH
GICKGMSNQNIADELYLSIDTVKSHVHNLLQKLPARDRTHAVVVAFRDGLVELPQRLPRW
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHHHHCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]