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The map label for this gene is atpA

Identifier: 124022193

GI number: 124022193

Start: 478875

End: 480392

Strand: Direct

Name: atpA

Synonym: P9303_04831

Alternate gene names: 124022193

Gene position: 478875-480392 (Clockwise)

Preceding gene: 124022192

Following gene: 124022194

Centisome position: 17.85

GC content: 52.31

Gene sequence:

>1518_bases
ATGGTTTCCATCCGCCCCGACGAGATCAGCGCGATTCTCAAGCAGCAGATCTCCGACTATGACAAGTCGGTTTCCGTCAG
CAACGTCGGCACTGTTCTGCAGATTGGTGACGGTATCGCTCGTGTCTATGGCCTTGAGCAGGTCATGGCTGGCGAACTGG
TGGAATTTGAGGATGGCACTGAAGGGATCGCCCTCAATTTGGAGGACGACAATGTTGGTGCGGTGTTGATGGGTGAGGGT
GTTGGTATTCAGGAAGGCAGTACCGTCAAAGCCACTGGCAAGATTGCCTCAGTGCCCGTAAGCGATGAGATGCTGGGCAG
AGTGGTGACTCCTTTGGGTCAACCGATGGATGGCAAAGGCGATATCCCCAGCACTGAGAGTCGCTTGATTGAGTCGATAG
CTCCAGGCATCATCAAACGTAAGTCGGTGCATGAGCCGCTGCAGACAGGAATTACATCCATCGACTCGATGATTCCTATC
GGTAGGGGTCAGCGTGAGTTGATCATTGGTGACCGTCAGACAGGTAAGACCGCGATCGCTATCGACACGATCATCAACCA
GAAGGGAGAGGATGTTGTCTGTGTATATGTAGCTGTCGGCCAGAAGGCTGCCTCTGTGGCCAACGTGGTTGAGGTGCTTC
GCGAGAAGGGCGCTCTCGATTACACCGTGATTGTGGCAGCTAGTGCTTCCGACGCTGCAGCTCTGCAGTACTTAGCTCCA
TATACCGGCGCAGCTATCGCTGAATCCTTTATGTATAAAGGCAAGGCTACTTTGGTGATCTACGACGATCTAACAAAGCA
GGCTCAGGCCTATCGTCAGATGTCACTGCTGCTGCGTCGTCCTCCCGGTCGTGAAGCCTATCCAGGAGATGTTTTCTATT
GCCACAGCCGCTTGCTTGAGAGGGCTGCAAAGCTTTCAGATGCAATGGGAGGTGGTTCGATGACTGCTTTGCCGATTATT
GAAACCCAAGCAGGAGACGTGTCGGCTTATATCCCTACCAATGTGATTTCGATCACGGATGGTCAGATTTTCTTGAGTTC
AGATCTTTTCAACTCAGGATTGCGTCCTGCCATCAACGTTGGCATTTCAGTGAGCCGGGTTGGTGGTGCTGCGCAAACCA
AAGCGATCAAAAAGATTGCTGGCACGTTGAAGCTTGAGTTGGCTCAGTTTGATGAATTGGCTGCTTTCTCTCAGTTCGCC
TCTGATTTAGATGAAGCAACTCAGAAGCAGTTGGGGCGGGGTAAGCGACTGCGCGAGCTGCTTAAGCAGCCTCAGTTTGC
ACCGCTGAATTTGGCTGAGCAGGTTGCGATCGTTTATGCAGGAGTGAAAGGCTTGATTGATGAGGTGCCAGAGGATCAGG
TCACTCAGTTTTCCCGTGAATTGCGTGATTACCTCAAGACCAACAAGCCCGAGTACATCACCAAAGTTCAGACTGAGAAA
GTGCTCAACGAGGATGCTGAGACCATTCTCAAGGCCGCCATCAACGAGGTGAAGTCGTCGATGCTGGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
TGCTGGACAGGTTCGACGACTTGGCCTGGCACTGGCCAAGGTGAGCTAGCTCCCTACCTTTTTCCCTTTCTCACCCTCTT
CCTCAACACCAACGCCTCCC

Downstream 100 bases:

>100_bases
CCCTGAAGGTAAACCCGGAGAACCCTATCCATGGCGAACCTCAAGGACATCCGCGACCGGATCGTTTCCGTTAAGAACAC
CAGAAAGATTACTGAGGCGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDAAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA

Sequences:

>Translated_505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDAAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA
>Mature_505_residues
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGTEGIALNLEDDNVGAVLMGEG
VGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKGDIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDAAALQYLAP
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
VLNEDAETILKAAINEVKSSMLASA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=59.1269841269841, Blast_Score=593, Evalue=1e-169,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=59.1269841269841, Blast_Score=593, Evalue=1e-169,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=29.8013245033113, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI19913426, Length=341, Percent_Identity=29.6187683284457, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI32189394, Length=395, Percent_Identity=23.5443037974684, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=53.7698412698413, Blast_Score=547, Evalue=1e-157,
Organism=Escherichia coli, GI1788251, Length=332, Percent_Identity=27.710843373494, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=24.8803827751196, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=492, Percent_Identity=59.349593495935, Blast_Score=597, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988080, Length=492, Percent_Identity=59.349593495935, Blast_Score=596, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988074, Length=492, Percent_Identity=55.6910569105691, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=28.0405405405405, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=315, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=395, Percent_Identity=24.3037974683544, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=46.1538461538462, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=497, Percent_Identity=57.3440643863179, Blast_Score=574, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=348, Percent_Identity=29.5977011494253, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=423, Percent_Identity=26.0047281323877, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=59.009900990099, Blast_Score=597, Evalue=1e-171,
Organism=Drosophila melanogaster, GI281361666, Length=346, Percent_Identity=28.0346820809249, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24646341, Length=346, Percent_Identity=28.0346820809249, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17136796, Length=346, Percent_Identity=28.0346820809249, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24638766, Length=404, Percent_Identity=24.009900990099, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28574560, Length=410, Percent_Identity=25.3658536585366, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PROM3 (A2C6X5)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016500.1
- ProteinModelPortal:   A2C6X5
- SMR:   A2C6X5
- STRING:   A2C6X5
- GeneID:   4778866
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_04831
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   TKQTLNR
- ProtClustDB:   PRK09281
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 53980; Mature: 53980

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGAVLMGEGVGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCC
DIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPIGRGQRELIIGDRQTGKTAIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDAAALQYLAP
EEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHCC
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLE
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLNEDAETILKAAINEVKSSMLASA
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSIRPDEISAILKQQISDYDKSVSVSNVGTVLQIGDGIARVYGLEQVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCEECCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGAVLMGEGVGIQEGSTVKATGKIASVPVSDEMLGRVVTPLGQPMDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHCCCCCCCCC
DIPSTESRLIESIAPGIIKRKSVHEPLQTGITSIDSMIPIGRGQRELIIGDRQTGKTAIA
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTIINQKGEDVVCVYVAVGQKAASVANVVEVLREKGALDYTVIVAASASDAAALQYLAP
EEHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHCC
YTGAAIAESFMYKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYCHSRLLE
CCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFAPLNLAEQVAIVYAGVKGLIDEVPEDQVTQFSRELRDYLKTNKPEYITKVQTEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLNEDAETILKAAINEVKSSMLASA
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA