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The map label for this gene is atpH

Identifier: 124022192

GI number: 124022192

Start: 478275

End: 478823

Strand: Direct

Name: atpH

Synonym: P9303_04821

Alternate gene names: 124022192

Gene position: 478275-478823 (Clockwise)

Preceding gene: 124022191

Following gene: 124022193

Centisome position: 17.83

GC content: 53.73

Gene sequence:

>549_bases
ATGCCACTGCTTAATACCATTACCACCCCCTATGCCGAGGCCTTTCTTCAAGTGGCTGAAAGCCGCAAGGAAGTCGATCA
GGTGGTTGATCAGGCAAAGGCAGTTCTGGCCTTGTGGAACGACTGCCCTGAGCTAAGTGGGGCAATGGCCTCACCCGTTT
TGGAAGTGGAGGCCAAGAAGGCTGCCTTGCAAAAGCTTTTTGCTAATCAGGTCACACCTTCTTTCCTCAACCTGCTGAAG
CTGCTCGCTGATCGTCAGCGAATCGGCGTTTTGGATGCGGTGCTTGAGCGCTTGATTGAGCTCTATCGCGAGCAACGCAA
CATCGCTCTCGCCACAGTGACCTCTGCTGCTGAACTCAGTGAGCAACAACAGGCTGCGCTGCAAAAGAAAGTGCAGGCTG
TGGCCAATACCGACAAGCTGGAGATCAATCTCAAAATTGATCCAGATTTAATCGGTGGTTTCGTTGTCAACGTCGGCTCC
AAGGTGATCGACGCCAGCGTTGCTGGACAGGTTCGACGACTTGGCCTGGCACTGGCCAAGGTGAGCTAG

Upstream 100 bases:

>100_bases
TGGCGATCGAGAATGCACTATCTGCTTTACCTGGGAAACTCAATGCCGATGCTCAAGCCCAGTTGGTGAGTCAGTCCATC
AAAAACCTTGGGGAAGCCTG

Downstream 100 bases:

>100_bases
CTCCCTACCTTTTTCCCTTTCTCACCCTCTTCCTCAACACCAACGCCTCCCATGGTTTCCATCCGCCCCGACGAGATCAG
CGCGATTCTCAAGCAGCAGA

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MPLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKKAALQKLFANQVTPSFLNLLK
LLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELSEQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGS
KVIDASVAGQVRRLGLALAKVS

Sequences:

>Translated_182_residues
MPLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKKAALQKLFANQVTPSFLNLLK
LLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELSEQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGS
KVIDASVAGQVRRLGLALAKVS
>Mature_181_residues
PLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKKAALQKLFANQVTPSFLNLLKL
LADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELSEQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGSK
VIDASVAGQVRRLGLALAKVS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=173, Percent_Identity=25.4335260115607, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1790173, Length=185, Percent_Identity=30.2702702702703, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984717, Length=171, Percent_Identity=28.6549707602339, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984710, Length=171, Percent_Identity=28.6549707602339, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647054, Length=164, Percent_Identity=28.0487804878049, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_PROM3 (A2C6X4)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001016499.1
- ProteinModelPortal:   A2C6X4
- SMR:   A2C6X4
- STRING:   A2C6X4
- GeneID:   4777696
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_04821
- eggNOG:   COG0712
- HOGENOM:   HBG668108
- OMA:   MSTNAIA
- ProtClustDB:   PRK13429
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 19701; Mature: 19570

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKK
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHHHHHH
AALQKLFANQVTPSFLNLLKLLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGSKVIDASVAGQVRRLGLALAK
HHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VS
CC
>Mature Secondary Structure 
PLLNTITTPYAEAFLQVAESRKEVDQVVDQAKAVLALWNDCPELSGAMASPVLEVEAKK
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHHHHHH
AALQKLFANQVTPSFLNLLKLLADRQRIGVLDAVLERLIELYREQRNIALATVTSAAELS
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EQQQAALQKKVQAVANTDKLEINLKIDPDLIGGFVVNVGSKVIDASVAGQVRRLGLALAK
HHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA