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The map label for this gene is pgm [H]

Identifier: 124021982

GI number: 124021982

Start: 283178

End: 284836

Strand: Reverse

Name: pgm [H]

Synonym: P9303_02691

Alternate gene names: 124021982

Gene position: 284836-283178 (Counterclockwise)

Preceding gene: 124021984

Following gene: 124021978

Centisome position: 10.62

GC content: 54.97

Gene sequence:

>1659_bases
ATGACCAGCTCGGCCCAGACGGGACCCACACAGCGCCAGGTACATCTGAACACACCCTTCAACGACCAAAAACCAGGGAC
CTCCGGCCTACGCAAAAGCAGCAAGCAATTCGAACAAACCAATTACCTGGAGAGCTTCATTGAAGCAATCTTCCAAACCC
TGCCTGGCGTTGAGGGGGGGACTCTGATCTTGGGGGGAGATGGTCGCTACGGCAATCAGCGCGCCATTGATGTGATCCTG
CGTATGGGTGCTGCTCATGGCCTAAGCCGAGTGATTACCACCACAAATGGCATTCTCTCCACGCCGGCAGCATCCCATCT
CATCCGTGCCAACAAGGCCATCGGAGGAATCATCCTTTCCGCGAGCCACAACCAAGGCGGTCCAGATGGCGACTTCGGCG
TCAAAGTCAACGGTGCCAATGGTGGTCCAGCAGCAGAATCACTCACAAACGCGATCTACGCATGTAGCCAAGCTTTAGAG
AGATACAGCCTTGTCGATGCAGACGTAATCCCACTTGAAACCCCCGGCCACCATGCCATCGGTGCCATGGCTGTAGACGT
GATCGACGGCGTTGAAGACTATGTAGAGCTGATGCAGAAGTTGTTCGACTTCGGGCGCATCAAAGACCTCATCAAAACCG
ACTTCCCCGTCGTGTTTGATGCAATGCATGCTGTCACTGGTCCCTATGCAAAACGGCTACTGGAAGGACTTCTCGGTGCC
CCAACTGGCTCTGTGCGCAACGGAGTTCCGCTTGAGGATTTTGGTGGAGGCCACCCAGATCCCAACCTCACCTACGCCGC
TGAACTGGCAAACCTCCTCCTCAATGGCAAGGCCTACAGCTTTGGTGCCGCCTGCGATGGTGATGGCGACCGCAACATGA
TCCTGGGCAGAGGTTGCTTCGTTAACCCAAGTGACAGCCTTGCAATCCTGGCTGCTAATGCCAACGTTGCACCGGCCTAT
GCCGATGGGCTTTCTGGTGTAGCCCGCTCCATGCCCACGAGCGCCGCAGTGGATGTTGTGGCCAAAGAACTCAATATCGA
CTGTTTTGAAACTCCCACCGGGTGGAAGTTTTTCGGCAACCTGCTTGATGCAGGTCGAATCACCCTCTGTGGTGAAGAAA
GCTTCGGCACTGGCAGCAACCACGTGCGTGAGAAGGATGGACTATGGGCAGTGCTCTTCTGGCTACAGATCCTGGCAGAG
CGACGGTGCAACGTCGCTGATGTGATGACACAGCATTGGAGTCGTTTTGGACGCCATTACTACTCCCGTCACGACTACGA
GGCGATTGCTAGTGAAAATGCTCATGGTCTTTACGACCGGTTGGAGAGCATGCTTCCTCGACTAATCGGTCAACCATTCG
CCGGGCGCCAAGTGAGCCAAGCGGACAATTTTAGATATAGCGATCCAGTGGATGGCTCAGAGACACAATCTCAGGGTCTA
CGCATCCTGCTGGAAGACGGCAGCAGAGTCGTGGTTCGACTCTCGGGCACCGGCACCAAAGGTGCCACATTGCGCGTTTA
TCTAGAACGCTACGAACCTAGTCATGGCAACTTAAATCAAGATCCCCAGCATGCTCTGGCCGATCTCATCAATGGCATCG
ATGCGCTTGCCGAAATTCAAAAGCGCACTGGGATGCAACGACCAACGGTGATCACTTGA

Upstream 100 bases:

>100_bases
AATGATCTTTGCGAACACTAGCCGCGAGAACTGGAGGGGGCCAAAACAGGATCGATGATTGCGTTTGATTAGGTTCGATT
AAGAACTGCCTTCGTCTCTG

Downstream 100 bases:

>100_bases
TCTCAGCGCAGCCACCACTCCCTTGGGCGGCGGTGATACTCCGCCTCGGTGCTGCTTTGTTGCAGCTGGCGCATGCTTTC
AATGACCACTGCTCCAAGAG

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGGDGRYGNQRAIDVIL
RMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALE
RYSLVDADVIPLETPGHHAIGAMAVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVTGPYAKRLLEGLLGA
PTGSVRNGVPLEDFGGGHPDPNLTYAAELANLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDSLAILAANANVAPAY
ADGLSGVARSMPTSAAVDVVAKELNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAE
RRCNVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYDRLESMLPRLIGQPFAGRQVSQADNFRYSDPVDGSETQSQGL
RILLEDGSRVVVRLSGTGTKGATLRVYLERYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQRPTVIT

Sequences:

>Translated_552_residues
MTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGGDGRYGNQRAIDVIL
RMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALE
RYSLVDADVIPLETPGHHAIGAMAVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVTGPYAKRLLEGLLGA
PTGSVRNGVPLEDFGGGHPDPNLTYAAELANLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDSLAILAANANVAPAY
ADGLSGVARSMPTSAAVDVVAKELNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAE
RRCNVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYDRLESMLPRLIGQPFAGRQVSQADNFRYSDPVDGSETQSQGL
RILLEDGSRVVVRLSGTGTKGATLRVYLERYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQRPTVIT
>Mature_551_residues
TSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGGTLILGGDGRYGNQRAIDVILR
MGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILSASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALER
YSLVDADVIPLETPGHHAIGAMAVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVTGPYAKRLLEGLLGAP
TGSVRNGVPLEDFGGGHPDPNLTYAAELANLLLNGKAYSFGAACDGDGDRNMILGRGCFVNPSDSLAILAANANVAPAYA
DGLSGVARSMPTSAAVDVVAKELNIDCFETPTGWKFFGNLLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAER
RCNVADVMTQHWSRFGRHYYSRHDYEAIASENAHGLYDRLESMLPRLIGQPFAGRQVSQADNFRYSDPVDGSETQSQGLR
ILLEDGSRVVVRLSGTGTKGATLRVYLERYEPSHGNLNQDPQHALADLINGIDALAEIQKRTGMQRPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=569, Percent_Identity=50.2636203866432, Blast_Score=569, Evalue=1e-162,
Organism=Homo sapiens, GI21361621, Length=555, Percent_Identity=50.4504504504504, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI133922562, Length=556, Percent_Identity=47.6618705035971, Blast_Score=502, Evalue=1e-142,
Organism=Homo sapiens, GI290463104, Length=369, Percent_Identity=52.8455284552846, Blast_Score=399, Evalue=1e-111,
Organism=Homo sapiens, GI239741729, Length=123, Percent_Identity=45.5284552845528, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI239743670, Length=114, Percent_Identity=46.4912280701754, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1786904, Length=425, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=559, Percent_Identity=48.8372093023256, Blast_Score=518, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6323752, Length=578, Percent_Identity=43.598615916955, Blast_Score=474, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6322722, Length=560, Percent_Identity=43.5714285714286, Blast_Score=450, Evalue=1e-127,
Organism=Drosophila melanogaster, GI17864244, Length=558, Percent_Identity=46.9534050179211, Blast_Score=516, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59243; Mature: 59112

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGG
CCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLILGGDGRYGNQRAIDVILRMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILS
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
ASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALERYSLVDADVIPLETPGHHAI
ECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
GAMAVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVTGPYAKRLLEGLLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCC
PTGSVRNGVPLEDFGGGHPDPNLTYAAELANLLLNGKAYSFGAACDGDGDRNMILGRGCF
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCE
VNPSDSLAILAANANVAPAYADGLSGVARSMPTSAAVDVVAKELNIDCFETPTGWKFFGN
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCHHHHHH
LLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAERRCNVADVMTQHWSRFGRHY
HHCCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YSRHDYEAIASENAHGLYDRLESMLPRLIGQPFAGRQVSQADNFRYSDPVDGSETQSQGL
HHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCHHCCC
RILLEDGSRVVVRLSGTGTKGATLRVYLERYEPSHGNLNQDPQHALADLINGIDALAEIQ
EEEEECCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KRTGMQRPTVIT
HHCCCCCCCCCC
>Mature Secondary Structure 
TSSAQTGPTQRQVHLNTPFNDQKPGTSGLRKSSKQFEQTNYLESFIEAIFQTLPGVEGG
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TLILGGDGRYGNQRAIDVILRMGAAHGLSRVITTTNGILSTPAASHLIRANKAIGGIILS
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
ASHNQGGPDGDFGVKVNGANGGPAAESLTNAIYACSQALERYSLVDADVIPLETPGHHAI
ECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHH
GAMAVDVIDGVEDYVELMQKLFDFGRIKDLIKTDFPVVFDAMHAVTGPYAKRLLEGLLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCC
PTGSVRNGVPLEDFGGGHPDPNLTYAAELANLLLNGKAYSFGAACDGDGDRNMILGRGCF
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCE
VNPSDSLAILAANANVAPAYADGLSGVARSMPTSAAVDVVAKELNIDCFETPTGWKFFGN
ECCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEECCCCCHHHHHH
LLDAGRITLCGEESFGTGSNHVREKDGLWAVLFWLQILAERRCNVADVMTQHWSRFGRHY
HHCCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YSRHDYEAIASENAHGLYDRLESMLPRLIGQPFAGRQVSQADNFRYSDPVDGSETQSQGL
HHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCCCCCHHCCC
RILLEDGSRVVVRLSGTGTKGATLRVYLERYEPSHGNLNQDPQHALADLINGIDALAEIQ
EEEEECCCEEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KRTGMQRPTVIT
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]