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The map label for this gene is mexB [H]

Identifier: 124021980

GI number: 124021980

Start: 279449

End: 282886

Strand: Direct

Name: mexB [H]

Synonym: P9303_02671

Alternate gene names: 124021980

Gene position: 279449-282886 (Clockwise)

Preceding gene: 124021979

Following gene: 124021981

Centisome position: 10.42

GC content: 45.78

Gene sequence:

>3438_bases
ATGTCTGCATCAAATAACTTTATTACGCGACCTGTTTTAGCAACAGTTTGCAGTTTGTTGATCGTCATTGCGGGACTGAT
ATCTATCCCTATTTTGCCAGTTGAAATGCTTCCGGATATTGCTCCGCCAACAGTAAAAGTAAATTCAATTTACACCGGTG
CCGATGCTGAATCGGTTGAGCAGGGTGTGACCAGTGTGCTGGAGCAGCAGATTAATGGGGTGGAGAATATGGACTATTTA
ACTTCCTCAAGCTCGGCTGATGGGGTGAGCTCGATTGCTGTTGCGTTCGAAAGTGGTAGTAATAGCGATATTAATCAAGT
TAATGTTCAGAACAGGGTTGCGCTGGCAGAGCCACAGTTGCCGGAAGAAGTGCGTAAGGCAGGGGTGAGTGTTAATAAGG
CTTCCAATTCTATCTTGCTTCTTTATAATTTTGTTAGTGAAGATCCAAGCAATATTGAATATAGTGTAGAAACGATTAGT
GGGCTGCTAGATCTGGGTCTAACGGACGAGGTTAAGCGGGTTAAGGGAGTAGGTGAAGTGACCTACTTTGGTAATCGTAA
GGTTGCTTTTAGGCTTTGGCTGGACAATGAAAAGCTTGAGGTTTTTGGCCTGACTTCAGCGGATGTAATGGGGGCGATTG
AAAGCCAGAACCGTTTGGTTCCTGCTGGGAGTATAGGAGGTGAACCATCTGCAGAAGGGCAGATATTTACTTTTCCTGTT
CAATTAAATGGCCGCCTTGTGAGCATTGGAGACTTTGAAAATATGGTCGTTAGGACCACAGATGATGGTGGATTAGTGAG
GTTTAGTGATGTCGGTCGTGTTGTGCTTGGTGGTGAAAGCTATTCCAACAGCGCTACGGATTTGCAGGCAGTCCCTTCTG
TGAGTATGGCTGTTTATCAATTGAGTGGCAGCAATGCTCTTGAGGTTTCTAATGGAGTAAAAGATGTTCTCGAAGAATTT
ACCGCCAAAATGCCTGTCGGCATGAAGATGGAGAAAATCTATGACAATACAGATTTTATTAATGCATCAATTAATGGAGT
GACCAATTCGCTTAGAGATTCGATCATTTTGGTGGTTCTTATTCTGTTTGTATTTTTACAGAATTGGAAAGCTACTTTGG
TGCCTGGTATTGCCATCCCTGTTGCGCTTGTTGGAACATTCTCTCTGGTTTTAGGGTTTGGCTTCTCGCTCAACCAGCTC
ACTTTATTTGGATTGGTTCTTGCTACAGGATTAGTGGTTGATGATGCAATCACAGTGATTGAAGATACCTCAACCAAGAA
AGCATCAGGGATGACTGCCTTGGAAGCTGCGAAGTCAACAATGGATGAGCTTTTCTCTGCAGTTATTGCTACATCCTTGG
TTCTTTTCTCAGTTTTTTTGCCAGTGTTGTTTTTCCCTGGCGCTACGGGTTCGATCTACAAGCAGTTTGCAGCAACGATT
ATTTTCGCGATCGCGATTTCTACCTTTAATGCTTTAACTTTTTCTCCCATGCTTTCTGCCTTGCTTTTGGGCCGGGAAGG
CACAGCTCCGGGACGCAATACATATGCAATTTCTGGTGCAGTCATTGGGTTTATATACGGACTATTAGTTGTTGGTGGTG
GTGCGGCGCTGGCCTTGATCCCTACAGCAATGGCTGCAATTCTTGGCTTTGTGCTGTCTAGCTTGACTGGCCGTTCGTTG
AGGCTGCCATTCTCTGTTGCAGGGGCTGTGATTGGCCTTTTCATCGCAGGAGTGTCAAATCCCTTGCCAGTCGTTTTATT
CGCTGGCCTTGGCTTGACCTTGGGTTGGTTTACACCATGGATTTTCAGTCATTTCAATCGCATTTATTCCGTCTTTGAGC
AGCGCTATGCCGATCTGCTCGAGTGGGTTCTTGGCCGCCGTTCTCTTGTGATGGGAATTCTTGCGGTAGGCGTTCTGCTT
ACCGGGGTTGCTTTTACTGCGATTCCAGGTGGATTTGTGCCTACTGAAGACCAGGGCTATGCCATCGGCGTGTTGCAGGC
CCCAGAAGGTGTGTCTACTCAGGTCACCGAGAAGATTAATAAGCAAGTTGCTGAGATATTGCGCAGCGAACCCGATATCA
CTTCAGCAGCAATTTTCAGTGGAGCAAGTTTTGATGGCAATAGCCCTAATAAAGGATTGTTTTTTATTGGGATGCGTAAT
TGGGATGAGCGCAAAAAGCGTGATCAATCTGCTGATGCAATTGTTGGACGGCTAAATCAGAAGTTCTTTGGGGCTATTGA
TGGCGCGAGGATTTTTGTTGTAGAGCCACCTGCGATTCCTGGATACGGCATTGGCAGTGGATTTGAGTTCCAGTTACTTG
ATAAGAGTGGAGGTGCTTATGGCTTAAACAACTTCTTTGCCTCAGCTGGTCAAATGATTCAGCAGGCGAATGCAAATCCA
TTGTTGAGCAGTGTACGGACTTTATTCTCTCCTGAATCTCCGCAGCTACGAGTTGAGGTCGATAGGGACATTATGGCCTC
TCTTGATATTGACTTCAGCTCTGCAATGCGTGTGTTTAGCGCTAATTTTGCAGGCGCCTATGTTAATGATACCTTCCAGG
AAGGTAAGGTTCGTCGTGTTTATGTTCAGGCCGATGAATTGGGTCGGTCTGCTCCTCAAAAGCTAGCTTCAATTTACGTT
AATAATCGGGCGGGTGAGCAGATTCAGCTCTCGGAATTTTTAACAGTTGAACCTTCAGTTGGGCCAAGTGTGATCTCTCA
CTTTAACCTTTACAGATCGATAAAAATAGAAGGGTCACCTGCTGCTGGTAAGAGCTCGGGGCAGGCAATTAATGGTATGA
AGGAGCTTTTTGCAGCTCAGAATCTTAACAGCCTCGGATTTGATTGGACAGGGATATCTCGAGAGGAAGTAAAAGCTGGT
GCACTAGCTGTTGTGATTTTTGCACTGGGAATTTTGGTGGTTTATCTCGTGCTTGCAGCTCAATACGAGAGTTATGCAGA
CCCTCTGATTATTTTGATGACAGTTCCTACTGCAATGCTTGGAGCCTTGTTGTTTCTGGCATTGCGTGGCGAGGTTCTCA
ACATTTATGCACAGGTTGGCCTTGTGATGTTGATTGGTCTAGCTGCCAAAAATGGGATCTTGATTGTTGATTTGGCTAAT
CAACGCATGGCGGAGGGAGTTACGGCCCTTGAAGCAGCAAGGCAGGCAGCCAAGTCGAGACTTAGGCCCATCATTATGAC
TGCTATTTCGTCTCTTTTTGGCTTTATGCCGTTGGTCTTGGCTAGCGGAGCAGGAGCCCGCAGCCAAGCTTCTCTTGGCA
CGGTTGTATTCGGTGGCCTTTTAGTTGCCACTTTCCTTTCGCTGTTTGTTGTGCCTGTCTTTTACGTCGTTGTTAAAGCT
CTTGTAGGCACCTTTAGTGATACAGAACAAGGCAACACTAATTTACTTAATTCGGGAGAACCCTCTGGGCAGGGATAA

Upstream 100 bases:

>100_bases
AGTTACAAAAGGGCTCAAACTTGGCGAGCAGGTGATCACAACAAATCTTTTGAAATTGAGACATGGCATGCCTGTTTCTG
TTAAAAACTGAGGCAAATAG

Downstream 100 bases:

>100_bases
ACCAATGAACCGCTCTCGTTCAATAAGAAACAAGCCCTTCAGCGGTACGAGGGTATTGATAGCGCTGCTGGTGGGGTTCT
TCCTCGGAGGTCTTGTTGCC

Product: RND family multidrug efflux transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1145; Mature: 1144

Protein sequence:

>1145_residues
MSASNNFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYL
TSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEEVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETIS
GLLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGSIGGEPSAEGQIFTFPV
QLNGRLVSIGDFENMVVRTTDDGGLVRFSDVGRVVLGGESYSNSATDLQAVPSVSMAVYQLSGSNALEVSNGVKDVLEEF
TAKMPVGMKMEKIYDNTDFINASINGVTNSLRDSIILVVLILFVFLQNWKATLVPGIAIPVALVGTFSLVLGFGFSLNQL
TLFGLVLATGLVVDDAITVIEDTSTKKASGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNTYAISGAVIGFIYGLLVVGGGAALALIPTAMAAILGFVLSSLTGRSL
RLPFSVAGAVIGLFIAGVSNPLPVVLFAGLGLTLGWFTPWIFSHFNRIYSVFEQRYADLLEWVLGRRSLVMGILAVGVLL
TGVAFTAIPGGFVPTEDQGYAIGVLQAPEGVSTQVTEKINKQVAEILRSEPDITSAAIFSGASFDGNSPNKGLFFIGMRN
WDERKKRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQMIQQANANP
LLSSVRTLFSPESPQLRVEVDRDIMASLDIDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPQKLASIYV
NNRAGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLNSLGFDWTGISREEVKAG
ALAVVIFALGILVVYLVLAAQYESYADPLIILMTVPTAMLGALLFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLAN
QRMAEGVTALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVVVKA
LVGTFSDTEQGNTNLLNSGEPSGQG

Sequences:

>Translated_1145_residues
MSASNNFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYL
TSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEEVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETIS
GLLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGSIGGEPSAEGQIFTFPV
QLNGRLVSIGDFENMVVRTTDDGGLVRFSDVGRVVLGGESYSNSATDLQAVPSVSMAVYQLSGSNALEVSNGVKDVLEEF
TAKMPVGMKMEKIYDNTDFINASINGVTNSLRDSIILVVLILFVFLQNWKATLVPGIAIPVALVGTFSLVLGFGFSLNQL
TLFGLVLATGLVVDDAITVIEDTSTKKASGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNTYAISGAVIGFIYGLLVVGGGAALALIPTAMAAILGFVLSSLTGRSL
RLPFSVAGAVIGLFIAGVSNPLPVVLFAGLGLTLGWFTPWIFSHFNRIYSVFEQRYADLLEWVLGRRSLVMGILAVGVLL
TGVAFTAIPGGFVPTEDQGYAIGVLQAPEGVSTQVTEKINKQVAEILRSEPDITSAAIFSGASFDGNSPNKGLFFIGMRN
WDERKKRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQMIQQANANP
LLSSVRTLFSPESPQLRVEVDRDIMASLDIDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPQKLASIYV
NNRAGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLNSLGFDWTGISREEVKAG
ALAVVIFALGILVVYLVLAAQYESYADPLIILMTVPTAMLGALLFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLAN
QRMAEGVTALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVVVKA
LVGTFSDTEQGNTNLLNSGEPSGQG
>Mature_1144_residues
SASNNFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVEQGVTSVLEQQINGVENMDYLT
SSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQLPEEVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISG
LLDLGLTDEVKRVKGVGEVTYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGSIGGEPSAEGQIFTFPVQ
LNGRLVSIGDFENMVVRTTDDGGLVRFSDVGRVVLGGESYSNSATDLQAVPSVSMAVYQLSGSNALEVSNGVKDVLEEFT
AKMPVGMKMEKIYDNTDFINASINGVTNSLRDSIILVVLILFVFLQNWKATLVPGIAIPVALVGTFSLVLGFGFSLNQLT
LFGLVLATGLVVDDAITVIEDTSTKKASGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATII
FAIAISTFNALTFSPMLSALLLGREGTAPGRNTYAISGAVIGFIYGLLVVGGGAALALIPTAMAAILGFVLSSLTGRSLR
LPFSVAGAVIGLFIAGVSNPLPVVLFAGLGLTLGWFTPWIFSHFNRIYSVFEQRYADLLEWVLGRRSLVMGILAVGVLLT
GVAFTAIPGGFVPTEDQGYAIGVLQAPEGVSTQVTEKINKQVAEILRSEPDITSAAIFSGASFDGNSPNKGLFFIGMRNW
DERKKRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAYGLNNFFASAGQMIQQANANPL
LSSVRTLFSPESPQLRVEVDRDIMASLDIDFSSAMRVFSANFAGAYVNDTFQEGKVRRVYVQADELGRSAPQKLASIYVN
NRAGEQIQLSEFLTVEPSVGPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLNSLGFDWTGISREEVKAGA
LAVVIFALGILVVYLVLAAQYESYADPLIILMTVPTAMLGALLFLALRGEVLNIYAQVGLVMLIGLAAKNGILIVDLANQ
RMAEGVTALEAARQAAKSRLRPIIMTAISSLFGFMPLVLASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVVVKAL
VGTFSDTEQGNTNLLNSGEPSGQG

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1789666, Length=501, Percent_Identity=40.5189620758483, Blast_Score=388, Evalue=1e-108,
Organism=Escherichia coli, GI1786667, Length=500, Percent_Identity=40.6, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789930, Length=501, Percent_Identity=40.3193612774451, Blast_Score=378, Evalue=1e-105,
Organism=Escherichia coli, GI1788814, Length=515, Percent_Identity=37.2815533980583, Blast_Score=357, Evalue=4e-99,
Organism=Escherichia coli, GI1788390, Length=511, Percent_Identity=31.3111545988258, Blast_Score=230, Evalue=5e-61,
Organism=Escherichia coli, GI1788391, Length=532, Percent_Identity=29.5112781954887, Blast_Score=199, Evalue=1e-51,
Organism=Escherichia coli, GI1786788, Length=545, Percent_Identity=25.3211009174312, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 121317; Mature: 121186

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASNNFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHH
QGVTSVLEQQINGVENMDYLTSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQL
HHHHHHHHHHHCCCCCCHHHCCCCCCCCHHEEEEEEECCCCCCCCEECCCCCEEECCCCC
PEEVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISGLLDLGLTDEVKRVKGVGEV
HHHHHHCCCEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCHHHHHHCCCCCE
TYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGSIGGEPSAEGQIFTFPV
EEECCCEEEEEEEECCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEE
QLNGRLVSIGDFENMVVRTTDDGGLVRFSDVGRVVLGGESYSNSATDLQAVPSVSMAVYQ
EECCEEEEECCCCCEEEEECCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCEEEEEE
LSGSNALEVSNGVKDVLEEFTAKMPVGMKMEKIYDNTDFINASINGVTNSLRDSIILVVL
ECCCCCEEHHCCHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCHHHHHHHHHHHHHHHHH
ILFVFLQNWKATLVPGIAIPVALVGTFSLVLGFGFSLNQLTLFGLVLATGLVVDDAITVI
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
EDTSTKKASGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
ECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNTYAISGAVIGFIYGLLVVGGGAALALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHH
PTAMAAILGFVLSSLTGRSLRLPFSVAGAVIGLFIAGVSNPLPVVLFAGLGLTLGWFTPW
HHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IFSHFNRIYSVFEQRYADLLEWVLGRRSLVMGILAVGVLLTGVAFTAIPGGFVPTEDQGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
AIGVLQAPEGVSTQVTEKINKQVAEILRSEPDITSAAIFSGASFDGNSPNKGLFFIGMRN
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECC
WDERKKRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAY
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GLNNFFASAGQMIQQANANPLLSSVRTLFSPESPQLRVEVDRDIMASLDIDFSSAMRVFS
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHCCCCHHHHHHHHH
ANFAGAYVNDTFQEGKVRRVYVQADELGRSAPQKLASIYVNNRAGEQIQLSEFLTVEPSV
CCCCCCHHCCHHHCCCEEEEEEEHHHHCCHHHHHHHHHHCCCCCCCEEEECCEEEECCCC
GPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLNSLGFDWTGISREEVKAG
CHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
ALAVVIFALGILVVYLVLAAQYESYADPLIILMTVPTAMLGALLFLALRGEVLNIYAQVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMLIGLAAKNGILIVDLANQRMAEGVTALEAARQAAKSRLRPIIMTAISSLFGFMPLVL
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVVVKALVGTFSDTEQGNTNLLNSGE
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PSGQG
CCCCC
>Mature Secondary Structure 
SASNNFITRPVLATVCSLLIVIAGLISIPILPVEMLPDIAPPTVKVNSIYTGADAESVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEEEEEECCCHHHHH
QGVTSVLEQQINGVENMDYLTSSSSADGVSSIAVAFESGSNSDINQVNVQNRVALAEPQL
HHHHHHHHHHHCCCCCCHHHCCCCCCCCHHEEEEEEECCCCCCCCEECCCCCEEECCCCC
PEEVRKAGVSVNKASNSILLLYNFVSEDPSNIEYSVETISGLLDLGLTDEVKRVKGVGEV
HHHHHHCCCEEECCCCCEEEEEEECCCCCCCCEEEHHHHHHHHHCCCCHHHHHHCCCCCE
TYFGNRKVAFRLWLDNEKLEVFGLTSADVMGAIESQNRLVPAGSIGGEPSAEGQIFTFPV
EEECCCEEEEEEEECCCCEEEEECCHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEEE
QLNGRLVSIGDFENMVVRTTDDGGLVRFSDVGRVVLGGESYSNSATDLQAVPSVSMAVYQ
EECCEEEEECCCCCEEEEECCCCCEEEEECCCEEEECCCCCCCCCCCHHHCCCCEEEEEE
LSGSNALEVSNGVKDVLEEFTAKMPVGMKMEKIYDNTDFINASINGVTNSLRDSIILVVL
ECCCCCEEHHCCHHHHHHHHHHCCCCCCCHHHHCCCCCEEECCHHHHHHHHHHHHHHHHH
ILFVFLQNWKATLVPGIAIPVALVGTFSLVLGFGFSLNQLTLFGLVLATGLVVDDAITVI
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHEE
EDTSTKKASGMTALEAAKSTMDELFSAVIATSLVLFSVFLPVLFFPGATGSIYKQFAATI
ECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IFAIAISTFNALTFSPMLSALLLGREGTAPGRNTYAISGAVIGFIYGLLVVGGGAALALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHH
PTAMAAILGFVLSSLTGRSLRLPFSVAGAVIGLFIAGVSNPLPVVLFAGLGLTLGWFTPW
HHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
IFSHFNRIYSVFEQRYADLLEWVLGRRSLVMGILAVGVLLTGVAFTAIPGGFVPTEDQGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
AIGVLQAPEGVSTQVTEKINKQVAEILRSEPDITSAAIFSGASFDGNSPNKGLFFIGMRN
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCEEEEEECC
WDERKKRDQSADAIVGRLNQKFFGAIDGARIFVVEPPAIPGYGIGSGFEFQLLDKSGGAY
HHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEECCCCCC
GLNNFFASAGQMIQQANANPLLSSVRTLFSPESPQLRVEVDRDIMASLDIDFSSAMRVFS
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHCCCCHHHHHHHHH
ANFAGAYVNDTFQEGKVRRVYVQADELGRSAPQKLASIYVNNRAGEQIQLSEFLTVEPSV
CCCCCCHHCCHHHCCCEEEEEEEHHHHCCHHHHHHHHHHCCCCCCCEEEECCEEEECCCC
GPSVISHFNLYRSIKIEGSPAAGKSSGQAINGMKELFAAQNLNSLGFDWTGISREEVKAG
CHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
ALAVVIFALGILVVYLVLAAQYESYADPLIILMTVPTAMLGALLFLALRGEVLNIYAQVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVMLIGLAAKNGILIVDLANQRMAEGVTALEAARQAAKSRLRPIIMTAISSLFGFMPLVL
HHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGAGARSQASLGTVVFGGLLVATFLSLFVVPVFYVVVKALVGTFSDTEQGNTNLLNSGE
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PSGQG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]