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The map label for this gene is bepF [H]

Identifier: 124021979

GI number: 124021979

Start: 278312

End: 279439

Strand: Direct

Name: bepF [H]

Synonym: P9303_02661

Alternate gene names: 124021979

Gene position: 278312-279439 (Clockwise)

Preceding gene: 124021977

Following gene: 124021980

Centisome position: 10.37

GC content: 46.99

Gene sequence:

>1128_bases
GTGAGCTGGAAACTTTCCATAATCAGGCTGTTGAACAAGTCGTTAGTGCCGAATCAGCAGCGCGCTCTTGTCGTTTTTAC
GGTGCTGTTGGTTTGCGCCTGTGGCAAGGCGAAAATACCTTTCTCGCCGATTACCGTCAGCCAGATACCTGTGACGACGG
CTCAATTCACGGACGATATCGATACGGTGAGCACCTTGGAGGCGAAGGATGAGGTGCATCTTGCTGCACAAGCTTCTGGT
CGAATTATTGAGTTAAAGATTGATCAGGGTGATCAGGTTCAGCCTGGTCAGATGTTGGTTGTGCTTGATCAAGCTCAGAT
CCGTGCGGAATTGGCAGATTTCAAAGCTCAGGAGCAGAAGAACAAACTCAATTGGCAGCGATATGAATTCTTGGTCCCTC
AAGGAGCTGCTTCGGCATTGGATCGAGATGAATACAAGGCCCAATACATCGCCTCTCGAGAAAAGGTAAAAGCCACAGAA
GCAACGCTTGCATATAGCAATTTGCGTTCTCCAATTTCAGGGATTGTGGCTGATGTTGATGTCAAGGTTGGAGATGTTAT
CCGTTCTGGTGATCCATTCACCAAATTGATCAGAAACAACTGGCTTTTTGCTCGAGTTGAGGTGCCTGCCACATTCTCTG
ATCGGATCAAGATTGGCTTGCCTGTCTTTCTCAGCAAGACTGGATCGTCAGATGTGATGGCGACTGGTGAAATTAATTCT
GTGAGCCCGACTGTAAATAGAACTACCCAGGGCTTACTAGTGAAGGCAGCGTTTGAGAATGGTAATGGATCGTTGCGAAA
TGGCCAGCGCTTGCGAACGCGGGTTCAATTGGATACTAGAGAGGAGTTGTCTGTTCCGTTTGCTGCGGTAACACAAACTT
CGGGCCAGAGCTTTGTTTATCGAGTGGGAAGTTTCAAAGATCTTGAGGCTTTTTCTGGCAATGTTTCTCTTGATAAACTT
CGTAAGTTACCCCCCTCCACACGTTTTGCTTTGCAGACCCCTGTGACGTTGGGAAAATTACAGAAGCAGCACTATGCAGT
TACAAAAGGGCTCAAACTTGGCGAGCAGGTGATCACAACAAATCTTTTGAAATTGAGACATGGCATGCCTGTTTCTGTTA
AAAACTGA

Upstream 100 bases:

>100_bases
GGCGCTTTAGCTCCTGATCTCCCTGGTATGTGAACAGATCTTGATCCAATGAGCTCTGGCACTGGTGGACAATTCTTGCG
CTAGGGGGTGACTTGTTGTC

Downstream 100 bases:

>100_bases
GGCAAATAGATGTCTGCATCAAATAACTTTATTACGCGACCTGTTTTAGCAACAGTTTGCAGTTTGTTGATCGTCATTGC
GGGACTGATATCTATCCCTA

Product: membrane-fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLVCACGKAKIPFSPITVSQIPVTTAQFTDDIDTVSTLEAKDEVHLAAQASG
RIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATE
ATLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNWLFARVEVPATFSDRIKIGLPVFLSKTGSSDVMATGEINS
VSPTVNRTTQGLLVKAAFENGNGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFKDLEAFSGNVSLDKL
RKLPPSTRFALQTPVTLGKLQKQHYAVTKGLKLGEQVITTNLLKLRHGMPVSVKN

Sequences:

>Translated_375_residues
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLVCACGKAKIPFSPITVSQIPVTTAQFTDDIDTVSTLEAKDEVHLAAQASG
RIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATE
ATLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNWLFARVEVPATFSDRIKIGLPVFLSKTGSSDVMATGEINS
VSPTVNRTTQGLLVKAAFENGNGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFKDLEAFSGNVSLDKL
RKLPPSTRFALQTPVTLGKLQKQHYAVTKGLKLGEQVITTNLLKLRHGMPVSVKN
>Mature_374_residues
SWKLSIIRLLNKSLVPNQQRALVVFTVLLVCACGKAKIPFSPITVSQIPVTTAQFTDDIDTVSTLEAKDEVHLAAQASGR
IIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQKNKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEA
TLAYSNLRSPISGIVADVDVKVGDVIRSGDPFTKLIRNNWLFARVEVPATFSDRIKIGLPVFLSKTGSSDVMATGEINSV
SPTVNRTTQGLLVKAAFENGNGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVYRVGSFKDLEAFSGNVSLDKLR
KLPPSTRFALQTPVTLGKLQKQHYAVTKGLKLGEQVITTNLLKLRHGMPVSVKN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=334, Percent_Identity=24.5508982035928, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789929, Length=322, Percent_Identity=24.8447204968944, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41266; Mature: 41135

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKLSIIRLLNKSLVPNQQRALVVFTVLLVCACGKAKIPFSPITVSQIPVTTAQFTDDI
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHCCCC
DTVSTLEAKDEVHLAAQASGRIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQK
HHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
NKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEATLAYSNLRSPISGIVADVD
HCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECC
VKVGDVIRSGDPFTKLIRNNWLFARVEVPATFSDRIKIGLPVFLSKTGSSDVMATGEINS
EEHHHHHCCCCHHHHHHHCCEEEEEEECCCCCCCCEEECCEEEEECCCCCCEEEECCCCC
VSPTVNRTTQGLLVKAAFENGNGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVY
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHEEEEEECCHHHHCCCEEEEECCCCCEEEE
RVGSFKDLEAFSGNVSLDKLRKLPPSTRFALQTPVTLGKLQKQHYAVTKGLKLGEQVITT
ECCCCCCHHHHCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLLKLRHGMPVSVKN
HHHHHHCCCCEEECC
>Mature Secondary Structure 
SWKLSIIRLLNKSLVPNQQRALVVFTVLLVCACGKAKIPFSPITVSQIPVTTAQFTDDI
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHCCCC
DTVSTLEAKDEVHLAAQASGRIIELKIDQGDQVQPGQMLVVLDQAQIRAELADFKAQEQK
HHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHH
NKLNWQRYEFLVPQGAASALDRDEYKAQYIASREKVKATEATLAYSNLRSPISGIVADVD
HCCCCEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECC
VKVGDVIRSGDPFTKLIRNNWLFARVEVPATFSDRIKIGLPVFLSKTGSSDVMATGEINS
EEHHHHHCCCCHHHHHHHCCEEEEEEECCCCCCCCEEECCEEEEECCCCCCEEEECCCCC
VSPTVNRTTQGLLVKAAFENGNGSLRNGQRLRTRVQLDTREELSVPFAAVTQTSGQSFVY
CCCCCCCCCCCEEEEEEEECCCCCCCCCHHHEEEEEECCHHHHCCCEEEEECCCCCEEEE
RVGSFKDLEAFSGNVSLDKLRKLPPSTRFALQTPVTLGKLQKQHYAVTKGLKLGEQVITT
ECCCCCCHHHHCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
NLLKLRHGMPVSVKN
HHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]