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The map label for this gene is ribD [C]

Identifier: 124021920

GI number: 124021920

Start: 225595

End: 226311

Strand: Direct

Name: ribD [C]

Synonym: P9303_02071

Alternate gene names: 124021920

Gene position: 225595-226311 (Clockwise)

Preceding gene: 124021919

Following gene: 124021921

Centisome position: 8.41

GC content: 54.95

Gene sequence:

>717_bases
TTGCAAAAGCAGTTTTGGCTTCGTCTTGTCCTAGCGATCAGCTTGGATGGCCGGCTGGCGCCTGCGATTGGTGGGCCGGC
CCAATTGGGTGGAGTTGGTGATCGGCGGGTTTTAGAAGAGGCTTTGGCTTGGGCTGATGGGGCCTTGCTCGGTGCGGGAA
CGTTGCGTGCCCATCGCAGCACATGTTTGATTCGTGATCAGGACTTGCTGAACCAGCGCAAGTCTGCCGGGCATAGTGCG
CAGCCCACGGCGGTGGTTGTTAGTCGTCAGCAGTGGTATGCAGCAGAGGTGCCTTTCTTTCAACAGCCGATTGAGCGTTG
GCTGTTGAGCCCCCATTTCGCTAAAGCAAAGGGATCGAAAGATCCTTTGCTTCCTGTTGGTTACGAGCGTCAGGTGTTGT
TTGAGCAAGATTGGCCTCAGGCGCTCAATCATTTGGCTGAGCTTGGGCTGTTGAGACTTGTTTTGTTGGGTGGAGCTCAG
CTGGCCGCATCGCTATTGCAGGCTGATGTTGTCGATGAGTTGCAACTTACCCTCACCCCAAAATTGCTTGGTGGCATGCA
TGCATGGGTTCCCTTTCAGGGCGGTGGTTTGCCAGATGATCTTGGCGACGCTGAGGCTTGGCATTTGCAAACCGTTGAGC
CCTTAACTGACAATGAACTACTACTGCGTTACGAGCGGAAGCGCGTTGAAGGTTCCCGTGCGGACCGGCTTATTTGA

Upstream 100 bases:

>100_bases
AGGAAAGCCCTAATAATGCAGCTGAAGTCTATGCGGAAACCCCAAGGATTGAAGCCATCCCTGAGGTATTGCATGCTATG
GCGGCTCACTAGCCAAGCAT

Downstream 100 bases:

>100_bases
TTGAACTCTAGATAAAATCATTCTTTGGTTTTCCTGCTTATAGATTGAGTGAACTAAGAATGCTCGGCACTGATGCTGAT
GATTCATTCACTGTAATGTC

Product: RibD/RibG domain-containing protein

Products: 5-amino-6-(5-phosphoribosylamino)uracil; NADPH; H+

Alternate protein names: Riboflavin-Specific Deaminase; Pyrimidine Reductase Riboflavin Biosynthesis; Deaminase-Reductase Domain-Containing Protein; Pyrimidine Reductase; Bifunctional Deaminase-Reductase Domain Protein; Bifunctional Deaminase-Reductase-Like

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MQKQFWLRLVLAISLDGRLAPAIGGPAQLGGVGDRRVLEEALAWADGALLGAGTLRAHRSTCLIRDQDLLNQRKSAGHSA
QPTAVVVSRQQWYAAEVPFFQQPIERWLLSPHFAKAKGSKDPLLPVGYERQVLFEQDWPQALNHLAELGLLRLVLLGGAQ
LAASLLQADVVDELQLTLTPKLLGGMHAWVPFQGGGLPDDLGDAEAWHLQTVEPLTDNELLLRYERKRVEGSRADRLI

Sequences:

>Translated_238_residues
MQKQFWLRLVLAISLDGRLAPAIGGPAQLGGVGDRRVLEEALAWADGALLGAGTLRAHRSTCLIRDQDLLNQRKSAGHSA
QPTAVVVSRQQWYAAEVPFFQQPIERWLLSPHFAKAKGSKDPLLPVGYERQVLFEQDWPQALNHLAELGLLRLVLLGGAQ
LAASLLQADVVDELQLTLTPKLLGGMHAWVPFQGGGLPDDLGDAEAWHLQTVEPLTDNELLLRYERKRVEGSRADRLI
>Mature_238_residues
MQKQFWLRLVLAISLDGRLAPAIGGPAQLGGVGDRRVLEEALAWADGALLGAGTLRAHRSTCLIRDQDLLNQRKSAGHSA
QPTAVVVSRQQWYAAEVPFFQQPIERWLLSPHFAKAKGSKDPLLPVGYERQVLFEQDWPQALNHLAELGLLRLVLLGGAQ
LAASLLQADVVDELQLTLTPKLLGGMHAWVPFQGGGLPDDLGDAEAWHLQTVEPLTDNELLLRYERKRVEGSRADRLI

Specific function: Converts 2,5-Diamino-6-(Ribosylamino)-4(3h)-Pyrimidinone 5'-Phosphate Into 5-Amino-6-(Ribosylamino)-2,4(1h,3h)- Pyrimidinedione 5'-Phosphate. [C]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.193

Molecular weight: Translated: 26220; Mature: 26220

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQFWLRLVLAISLDGRLAPAIGGPAQLGGVGDRRVLEEALAWADGALLGAGTLRAHRS
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCEECCCHHHHHCC
TCLIRDQDLLNQRKSAGHSAQPTAVVVSRQQWYAAEVPFFQQPIERWLLSPHFAKAKGSK
EEEEECHHHHHHHHHCCCCCCCCEEEEECCHHEECCCCHHHHHHHHHHCCCCHHHCCCCC
DPLLPVGYERQVLFEQDWPQALNHLAELGLLRLVLLGGAQLAASLLQADVVDELQLTLTP
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECH
KLLGGMHAWVPFQGGGLPDDLGDAEAWHLQTVEPLTDNELLLRYERKRVEGSRADRLI
HHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQKQFWLRLVLAISLDGRLAPAIGGPAQLGGVGDRRVLEEALAWADGALLGAGTLRAHRS
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHCCCEECCCHHHHHCC
TCLIRDQDLLNQRKSAGHSAQPTAVVVSRQQWYAAEVPFFQQPIERWLLSPHFAKAKGSK
EEEEECHHHHHHHHHCCCCCCCCEEEEECCHHEECCCCHHHHHHHHHHCCCCHHHCCCCC
DPLLPVGYERQVLFEQDWPQALNHLAELGLLRLVLLGGAQLAASLLQADVVDELQLTLTP
CCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECH
KLLGGMHAWVPFQGGGLPDDLGDAEAWHLQTVEPLTDNELLLRYERKRVEGSRADRLI
HHHCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-amino-6-(5-phosphoribitylamino)uracil; NADP+

Specific reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP+ = 5-amino-6-(5-phosphoribosylamino)uracil + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA