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The map label for this gene is btuE [C]

Identifier: 124021875

GI number: 124021875

Start: 179466

End: 179945

Strand: Reverse

Name: btuE [C]

Synonym: P9303_01621

Alternate gene names: 124021875

Gene position: 179945-179466 (Counterclockwise)

Preceding gene: 124021878

Following gene: 124021869

Centisome position: 6.71

GC content: 53.12

Gene sequence:

>480_bases
ATGGCCATCAACATCAGCCAGATTGTGGTTCGCACTCCAGAAGGTGCTGAGAAATCCCTCAGCGAATACAACGGCACGGT
GCTGTTAATCGTGAATGTGGCCAGCCGATGTGGATTTACCAAGCAATACAAAGGCCTGCAAGCGCTGCAAGACACATACG
GCCCTAAGGGACTAAAGGTGCTGGGCTTTCCTTGCAACGACTTCGGAGCCCAGGAGCCCGGCACCCTCGAAGAGATCAAA
AGCTTCTGTTCCACGACCTACGGCGCCAGCTTCGAGTTGTTTGACAAGGTGCACGCCATGGACAAAACCACCGAGCCTTA
CACCACCCTCAATCAAACTGAACCAGCAGGGGATGTGGCTTGGAACTTCGAAAAGTTTCTTGTGGGTAAGGACGGCACCG
TGATCAAACGTTTCAAGAGCGGCGTGGAGCCTGAAAGCACTGAACTGAAAGGTGCGATCGAGCAAGCGTTGAACACCTAA

Upstream 100 bases:

>100_bases
TGGTTGCCCCCGTTGCCTCGTTCATCGGCCCGCCGTCAAGGCGAGCACACTGTATGGCGTATGGTCCTCGCTAGGGTCTT
GAAGACAAAATCGAATATCC

Downstream 100 bases:

>100_bases
TTACCAATGCGTCTACCCACCCACTGCATGGGATTCTGCAAGACCCAATTTTACAAGCAAAGTCAGCAAACGAAGGGCTT
GATCACGCCGATAGCCAAGC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MAINISQIVVRTPEGAEKSLSEYNGTVLLIVNVASRCGFTKQYKGLQALQDTYGPKGLKVLGFPCNDFGAQEPGTLEEIK
SFCSTTYGASFELFDKVHAMDKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVIKRFKSGVEPESTELKGAIEQALNT

Sequences:

>Translated_159_residues
MAINISQIVVRTPEGAEKSLSEYNGTVLLIVNVASRCGFTKQYKGLQALQDTYGPKGLKVLGFPCNDFGAQEPGTLEEIK
SFCSTTYGASFELFDKVHAMDKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVIKRFKSGVEPESTELKGAIEQALNT
>Mature_158_residues
AINISQIVVRTPEGAEKSLSEYNGTVLLIVNVASRCGFTKQYKGLQALQDTYGPKGLKVLGFPCNDFGAQEPGTLEEIKS
FCSTTYGASFELFDKVHAMDKTTEPYTTLNQTEPAGDVAWNFEKFLVGKDGTVIKRFKSGVEPESTELKGAIEQALNT

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=119, Percent_Identity=47.8991596638655, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI192455698, Length=131, Percent_Identity=38.9312977099237, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI75709200, Length=154, Percent_Identity=35.7142857142857, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=36, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4557629, Length=163, Percent_Identity=36.1963190184049, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI6006001, Length=143, Percent_Identity=39.1608391608392, Blast_Score=87, Evalue=7e-18,
Organism=Homo sapiens, GI41406084, Length=153, Percent_Identity=39.8692810457516, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI90903238, Length=132, Percent_Identity=34.8484848484849, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI33186887, Length=143, Percent_Identity=36.3636363636364, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1788003, Length=181, Percent_Identity=39.7790055248619, Blast_Score=134, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17535473, Length=159, Percent_Identity=41.5094339622642, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17506887, Length=153, Percent_Identity=41.1764705882353, Blast_Score=113, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193210707, Length=153, Percent_Identity=39.2156862745098, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=33.75, Blast_Score=99, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=28.8888888888889, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17550320, Length=174, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=49.2957746478873, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=35.7894736842105, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71999642, Length=70, Percent_Identity=41.4285714285714, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=153, Percent_Identity=39.2156862745098, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322228, Length=143, Percent_Identity=43.3566433566434, Blast_Score=121, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6322826, Length=137, Percent_Identity=40.1459854014599, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI85726443, Length=144, Percent_Identity=37.5, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656772, Length=149, Percent_Identity=37.5838926174497, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656777, Length=162, Percent_Identity=36.4197530864198, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656767, Length=162, Percent_Identity=36.4197530864198, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17354; Mature: 17223

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINISQIVVRTPEGAEKSLSEYNGTVLLIVNVASRCGFTKQYKGLQALQDTYGPKGLKV
CCCCHHEEEEECCCCHHHHHHHHCCEEEEEEEEHHHCCCCHHHHHHHHHHHHCCCCCCEE
LGFPCNDFGAQEPGTLEEIKSFCSTTYGASFELFDKVHAMDKTTEPYTTLNQTEPAGDVA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
WNFEKFLVGKDGTVIKRFKSGVEPESTELKGAIEQALNT
ECHHHEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AINISQIVVRTPEGAEKSLSEYNGTVLLIVNVASRCGFTKQYKGLQALQDTYGPKGLKV
CCCHHEEEEECCCCHHHHHHHHCCEEEEEEEEHHHCCCCHHHHHHHHHHHHCCCCCCEE
LGFPCNDFGAQEPGTLEEIKSFCSTTYGASFELFDKVHAMDKTTEPYTTLNQTEPAGDVA
EECCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
WNFEKFLVGKDGTVIKRFKSGVEPESTELKGAIEQALNT
ECHHHEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]