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The map label for this gene is asd [H]

Identifier: 124021786

GI number: 124021786

Start: 70114

End: 71145

Strand: Direct

Name: asd [H]

Synonym: P9303_00711

Alternate gene names: 124021786

Gene position: 70114-71145 (Clockwise)

Preceding gene: 124021778

Following gene: 124021787

Centisome position: 2.61

GC content: 53.88

Gene sequence:

>1032_bases
TTGCTTCCCATATCGTTTTTTCCCGATCGTCCCCTCACAGTTGCTGTGCTTGGTGCCAGTGGCGCAGTGGGTCAGGAGCT
GCTTCAGCTGCTGCAGGAACGCTCGTTTCCCATTGGTGAGTTGCGCTTATTGGCATCTGCGCGTTCTGCGGGCCATGTTC
AAGCTTGGAATGGCTCCAGCCTCGTCGTTCAGGAGGTGAGCGAAGCTGCTTTTGAGGGGGTTGATTTGGTGCTGGCCTCA
GCTGGTGGATCCGTATCGCGTCAGTGGCGGCAGGTGATCAACTCAGCCGGTGCGCTGATGATTGACAACTCCAGTGCCTT
CAGGATGGATGCCGACGTGCCACTCGTGGTGCCAGAGGTCAATCCTGAGGCGGTTGCAGAGCATCAGGGGGTGATTGCAA
ATCCGAATTGCACCACGATTTTGTTAACTCTGGTGCTGGCACCTTTGGCTGCAAGACGTGCTTTGCGTCGCGTTGTTGTC
AGCACCTATCAGTCGGCGAGTGGTGCAGGTGCACGCGCTATGGAGGAGCTCAAGCAGCTCACTCAGGTGGTTTTAGCGGG
CGACACGCCTTGTAGTGAAGTGCTTCCTCATTCCCTTGCCTTCAACTTGTTTCTGCACAACTCTCCATTGATGGCCAATA
GCTATTGCGAGGAGGAAATGAAGATGGTCAATGAAACGCGCAAAATTATGGGCCTTCCTGATTTGCGCTTTACCGCAACT
TGTGTTCGGGTGCCTGTACTTAGAGCCCATTCGGAGGCTGTGAATATTGAGTTTGACGAGCCTTTTCCAGTGGAAGAAGC
TCGCCAATTGCTGAAGGTGGCAGCGGGGCTCGAGTTAATCGAAGATTTTGAGCAGAATCGCTTTCCCATGCCTACCGATG
TCACTGATCGCGATCCGGTTGCGGTGGGTCGCATTCGGCAGGACATCAGTGATCCCAATGCTCTCGAGCTTTGGCTATGC
GGGGATCAGATCCGTAAAGGTGCCGCTCTAAATGCGATCCAAATTGCAGAATTGTTGTTGTCGTCATCATGA

Upstream 100 bases:

>100_bases
ACGTCTTGCCTGATTGAGGCTGTAGGGCTTTATCCCAGCTGGGTTCAATTTTTTATTGAGATCGAACCCATGAACTCAGT
CAATAACCTGATCTCACCGC

Downstream 100 bases:

>100_bases
GCTCTGCTGCTGAGTCGTCTCCAACTCCTTTTGGCCGTTTGCTGACGGCCATGGTTACACCTTTTGACGCTGATGGATGC
GTTGATCTGGCTTTGGCTGG

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLPISFFPDRPLTVAVLGASGAVGQELLQLLQERSFPIGELRLLASARSAGHVQAWNGSSLVVQEVSEAAFEGVDLVLAS
AGGSVSRQWRQVINSAGALMIDNSSAFRMDADVPLVVPEVNPEAVAEHQGVIANPNCTTILLTLVLAPLAARRALRRVVV
STYQSASGAGARAMEELKQLTQVVLAGDTPCSEVLPHSLAFNLFLHNSPLMANSYCEEEMKMVNETRKIMGLPDLRFTAT
CVRVPVLRAHSEAVNIEFDEPFPVEEARQLLKVAAGLELIEDFEQNRFPMPTDVTDRDPVAVGRIRQDISDPNALELWLC
GDQIRKGAALNAIQIAELLLSSS

Sequences:

>Translated_343_residues
MLPISFFPDRPLTVAVLGASGAVGQELLQLLQERSFPIGELRLLASARSAGHVQAWNGSSLVVQEVSEAAFEGVDLVLAS
AGGSVSRQWRQVINSAGALMIDNSSAFRMDADVPLVVPEVNPEAVAEHQGVIANPNCTTILLTLVLAPLAARRALRRVVV
STYQSASGAGARAMEELKQLTQVVLAGDTPCSEVLPHSLAFNLFLHNSPLMANSYCEEEMKMVNETRKIMGLPDLRFTAT
CVRVPVLRAHSEAVNIEFDEPFPVEEARQLLKVAAGLELIEDFEQNRFPMPTDVTDRDPVAVGRIRQDISDPNALELWLC
GDQIRKGAALNAIQIAELLLSSS
>Mature_343_residues
MLPISFFPDRPLTVAVLGASGAVGQELLQLLQERSFPIGELRLLASARSAGHVQAWNGSSLVVQEVSEAAFEGVDLVLAS
AGGSVSRQWRQVINSAGALMIDNSSAFRMDADVPLVVPEVNPEAVAEHQGVIANPNCTTILLTLVLAPLAARRALRRVVV
STYQSASGAGARAMEELKQLTQVVLAGDTPCSEVLPHSLAFNLFLHNSPLMANSYCEEEMKMVNETRKIMGLPDLRFTAT
CVRVPVLRAHSEAVNIEFDEPFPVEEARQLLKVAAGLELIEDFEQNRFPMPTDVTDRDPVAVGRIRQDISDPNALELWLC
GDQIRKGAALNAIQIAELLLSSS

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=335, Percent_Identity=35.8208955223881, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789841, Length=355, Percent_Identity=25.9154929577465, Blast_Score=92, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=28.4615384615385, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37098; Mature: 37098

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPISFFPDRPLTVAVLGASGAVGQELLQLLQERSFPIGELRLLASARSAGHVQAWNGSS
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCH
LVVQEVSEAAFEGVDLVLASAGGSVSRQWRQVINSAGALMIDNSSAFRMDADVPLVVPEV
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEECCC
NPEAVAEHQGVIANPNCTTILLTLVLAPLAARRALRRVVVSTYQSASGAGARAMEELKQL
CHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQVVLAGDTPCSEVLPHSLAFNLFLHNSPLMANSYCEEEMKMVNETRKIMGLPDLRFTAT
HHHHHCCCCCHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
CVRVPVLRAHSEAVNIEFDEPFPVEEARQLLKVAAGLELIEDFEQNRFPMPTDVTDRDPV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AVGRIRQDISDPNALELWLCGDQIRKGAALNAIQIAELLLSSS
HHHHHHHHCCCCCEEEEEEECHHHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLPISFFPDRPLTVAVLGASGAVGQELLQLLQERSFPIGELRLLASARSAGHVQAWNGSS
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCH
LVVQEVSEAAFEGVDLVLASAGGSVSRQWRQVINSAGALMIDNSSAFRMDADVPLVVPEV
HHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEECCC
NPEAVAEHQGVIANPNCTTILLTLVLAPLAARRALRRVVVSTYQSASGAGARAMEELKQL
CHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TQVVLAGDTPCSEVLPHSLAFNLFLHNSPLMANSYCEEEMKMVNETRKIMGLPDLRFTAT
HHHHHCCCCCHHHHCCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
CVRVPVLRAHSEAVNIEFDEPFPVEEARQLLKVAAGLELIEDFEQNRFPMPTDVTDRDPV
HHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AVGRIRQDISDPNALELWLCGDQIRKGAALNAIQIAELLLSSS
HHHHHHHHCCCCCEEEEEEECHHHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]