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The map label for this gene is dapA [H]

Identifier: 123969394

GI number: 123969394

Start: 1595969

End: 1596871

Strand: Reverse

Name: dapA [H]

Synonym: A9601_18621

Alternate gene names: 123969394

Gene position: 1596871-1595969 (Counterclockwise)

Preceding gene: 123969395

Following gene: 123969393

Centisome position: 95.63

GC content: 38.32

Gene sequence:

>903_bases
ATGATTACAGACAAAACTGAGTGTAATAATCCATTATTTGGAAGAATATTGACTGCAATGGTTACTCCATTCACTGAGAA
TGGAGATGTAGATTATGAACTAGCTATAAAACTTTCAAATTATCTTTTTGAGAACGGTTCCGATGGAATTGTGTTGTGCG
GTACTACTGGAGAATCTCCGACTCTTTCATGGGCGGAGCAGCATGATTTATTTATTGCGGTAAAAGGATCTTTGGATGCA
AGCTGTAAAGTAATAGTTGGCACTGGTAGCAATTGTACAAGCGAAGCTGTGGAAGCTACAAAAAAAGCTTACGACTCTGG
TGCCGACGGTGCTTTGGTCGTTGTTCCTTATTACAATAAGCCGCCTCAAGAAGGTCTTTATAAACATTTCAGTTCTATTG
CTAAATCTGCAAAGGATTTGCCTCTTATGCTCTACAACATTCCTGGCAGGACTGGATGCAATTTATTACCTGATACTGTG
AAGAAACTTATGGATTTCTCAAATATTCTCAGTATTAAAGCTGCAAGCGGTAGAATAGAAGAAGTAACAGAATTAAGAGC
TATTTGTGGCTCCGAACTCTCTGTATATAGTGGCGACGATTCATTGTTGCTTCCAATGTTATCGGTAGGTGCTGTAGGAG
TAGTAAGTGTTGCAAGTCATTTAGTTGGATTGCAATTGAAAGAGATGATTCATTCTTTTCAAAGTGGAAAGGTTTCCAAT
GCTCTTGCTATTCATGAAAAACTTCAGCCTCTTTTCAAAGCACTCTTTATGACTACTAATCCAATCCCAATTAAAGCTGC
TTTGGAGCTCTCGGGATGGGATGTAGGTAATCCTAGAAGTCCTTTGTCACCTTTAAACAATGACATGAAAAAGCAACTAT
CTTTTATCCTGAATTCCCTATAA

Upstream 100 bases:

>100_bases
GTCATCCTCATGGATTAGAATTATGGTTATGTGGAGATCAAATAAGAAAAGGAGCAGCTCTGAATGCTGTTCAAATAGCT
GAGTTATTAATTCCAAAAAA

Downstream 100 bases:

>100_bases
TAGGGATTATATTTAACTTGATAATTAAATTTAAATAAACCTTATTTGATTACAAGCAGGCCTTCATAAATTTCAAAATT
ATGCAATCAAGTACAAATTC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESPTLSWAEQHDLFIAVKGSLDA
SCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNKPPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTV
KKLMDFSNILSIKAASGRIEEVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSN
ALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL

Sequences:

>Translated_300_residues
MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESPTLSWAEQHDLFIAVKGSLDA
SCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNKPPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTV
KKLMDFSNILSIKAASGRIEEVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSN
ALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL
>Mature_300_residues
MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESPTLSWAEQHDLFIAVKGSLDA
SCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNKPPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTV
KKLMDFSNILSIKAASGRIEEVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSN
ALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=291, Percent_Identity=25.7731958762887, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI13540533, Length=299, Percent_Identity=28.4280936454849, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788823, Length=287, Percent_Identity=38.3275261324042, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1786463, Length=289, Percent_Identity=30.4498269896194, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082415, Length=243, Percent_Identity=28.8065843621399, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789620, Length=286, Percent_Identity=23.4265734265734, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32218; Mature: 32218

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHCCCCCCEEEEECCCCCC
TLSWAEQHDLFIAVKGSLDASCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNK
CCCCCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
PPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTVKKLMDFSNILSIKAASGRIE
CCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCHH
EVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSN
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITDKTECNNPLFGRILTAMVTPFTENGDVDYELAIKLSNYLFENGSDGIVLCGTTGESP
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHCCCCCCEEEEECCCCCC
TLSWAEQHDLFIAVKGSLDASCKVIVGTGSNCTSEAVEATKKAYDSGADGALVVVPYYNK
CCCCCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
PPQEGLYKHFSSIAKSAKDLPLMLYNIPGRTGCNLLPDTVKKLMDFSNILSIKAASGRIE
CCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCHH
EVTELRAICGSELSVYSGDDSLLLPMLSVGAVGVVSVASHLVGLQLKEMIHSFQSGKVSN
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALAIHEKLQPLFKALFMTTNPIPIKAALELSGWDVGNPRSPLSPLNNDMKKQLSFILNSL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA