Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 123969357

GI number: 123969357

Start: 1557937

End: 1558995

Strand: Reverse

Name: ruvB [H]

Synonym: A9601_18251

Alternate gene names: 123969357

Gene position: 1558995-1557937 (Counterclockwise)

Preceding gene: 123969359

Following gene: 123969356

Centisome position: 93.36

GC content: 32.48

Gene sequence:

>1059_bases
ATGGCAATAATTTCTTCCAATATAGGCGATAATGACTTTTCTTTTCGAAAAAAAGAACTTAGGCTAGTTGATTCAAAAAA
CATTCCAGAAGAAAAGAGAAATAATAATTTGAACTTAGCCCGGCCTCTTAATTTAAAAGAATTTATTGGCCAAGAACAAC
TTAAATCTTCTTTAAGAGTAGCTATAGATGCTTCAATTATTAGAAAAGAACCTTTGGAGCATACTCTTTTATATGGACAA
CCTGGTCTAGGTAAGACTACTCTTGCTTTTTTGATAGCCCACGAATTGAATACAAAATGTAGGATTGCGACTGCACCAGC
AATTGAAAGACCAAGAGATATTGTAGGTTTACTTCTTGGATTAAAAGAAGGTGAAGTTTTATTTATCGATGAGATACATC
GCTTAAATAGGTTAACTGAAGAGTTGTTATATTCTGCAATGGAGGATTTTAGACTTGACTTAACGATGGGAGCTAATAGA
GGAGCCCGTTGCAGAACAATTAATCTTCCTAGGTTTACTCTGATTGGTGCGACAACTAAATTAGCCTCAATAAGTGCACC
TCTAAGAGATAGATTTGGGATATCTCAGAAAATTGAATTCTATACATGTGATGAATTAAAACAAATTATTGTTAATTTCT
CCCGATTAATAAACCTCAATTTAGAAGATGAAGCATCTTATGATTTGGCAAAGATATCTCGAGGGACTCCAAGAATTGCA
TTAAGATTATTAAGACGAGTTAGAGATTATGCTCAAGTTGTTATGAAAACTAATACTATCTCAGTGAATTTAATAAAAAA
AGCTTTAAATTCTTACCAAATAGACGAAAAAGGATTGGATTCTTTAGATAGACACTATTTATCTTTTCTTAACCAAAACA
ATAATATTCCAATTGGCCTTGATTCAATTGCATCTGGGTTGGGCGATGATTCTTCAATGTTAGAATTTGTTGTTGAGCCA
TATCTTATTAAAATTGGTTTTCTTACGAGAACTCCTCGAGGAAGATTGCTTACTGCTTTAGGGAAAAAGTACATTGATTC
AAAAGATGATAACTTTTAA

Upstream 100 bases:

>100_bases
ATTTGCTTTATTAGTATTTTTTTTAACTTTGTTTGAATTTTTTGCCATTTTAGTTGTAAAAAATCTTTCTACTCAGAACA
ATTGCAATTAACCTTTCATT

Downstream 100 bases:

>100_bases
AAAAGTTAAGGTTTGTTTTTTATTAATTTTTATTTTTTTCAATATTTTTTATATTGCACCATGCTATTCATTATCTTCGA
GAGAGGATTTGTTTAAAAAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAIISSNIGDNDFSFRKKELRLVDSKNIPEEKRNNNLNLARPLNLKEFIGQEQLKSSLRVAIDASIIRKEPLEHTLLYGQ
PGLGKTTLAFLIAHELNTKCRIATAPAIERPRDIVGLLLGLKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANR
GARCRTINLPRFTLIGATTKLASISAPLRDRFGISQKIEFYTCDELKQIIVNFSRLINLNLEDEASYDLAKISRGTPRIA
LRLLRRVRDYAQVVMKTNTISVNLIKKALNSYQIDEKGLDSLDRHYLSFLNQNNNIPIGLDSIASGLGDDSSMLEFVVEP
YLIKIGFLTRTPRGRLLTALGKKYIDSKDDNF

Sequences:

>Translated_352_residues
MAIISSNIGDNDFSFRKKELRLVDSKNIPEEKRNNNLNLARPLNLKEFIGQEQLKSSLRVAIDASIIRKEPLEHTLLYGQ
PGLGKTTLAFLIAHELNTKCRIATAPAIERPRDIVGLLLGLKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANR
GARCRTINLPRFTLIGATTKLASISAPLRDRFGISQKIEFYTCDELKQIIVNFSRLINLNLEDEASYDLAKISRGTPRIA
LRLLRRVRDYAQVVMKTNTISVNLIKKALNSYQIDEKGLDSLDRHYLSFLNQNNNIPIGLDSIASGLGDDSSMLEFVVEP
YLIKIGFLTRTPRGRLLTALGKKYIDSKDDNF
>Mature_351_residues
AIISSNIGDNDFSFRKKELRLVDSKNIPEEKRNNNLNLARPLNLKEFIGQEQLKSSLRVAIDASIIRKEPLEHTLLYGQP
GLGKTTLAFLIAHELNTKCRIATAPAIERPRDIVGLLLGLKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANRG
ARCRTINLPRFTLIGATTKLASISAPLRDRFGISQKIEFYTCDELKQIIVNFSRLINLNLEDEASYDLAKISRGTPRIAL
RLLRRVRDYAQVVMKTNTISVNLIKKALNSYQIDEKGLDSLDRHYLSFLNQNNNIPIGLDSIASGLGDDSSMLEFVVEPY
LIKIGFLTRTPRGRLLTALGKKYIDSKDDNF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=299, Percent_Identity=45.4849498327759, Blast_Score=283, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 39835; Mature: 39704

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIISSNIGDNDFSFRKKELRLVDSKNIPEEKRNNNLNLARPLNLKEFIGQEQLKSSLRV
CCEEECCCCCCCHHHHHHHHHEECCCCCCHHHCCCCCCEECCCCHHHHCCHHHHHHHHHH
AIDASIIRKEPLEHTLLYGQPGLGKTTLAFLIAHELNTKCRIATAPAIERPRDIVGLLLG
HHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHC
LKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANRGARCRTINLPRFTLIGATTK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCEEEEECHHH
LASISAPLRDRFGISQKIEFYTCDELKQIIVNFSRLINLNLEDEASYDLAKISRGTPRIA
HHHCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHEECCCCCCCCCCHHHHCCCCHHHH
LRLLRRVRDYAQVVMKTNTISVNLIKKALNSYQIDEKGLDSLDRHYLSFLNQNNNIPIGL
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEH
DSIASGLGDDSSMLEFVVEPYLIKIGFLTRTPRGRLLTALGKKYIDSKDDNF
HHHHCCCCCCHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIISSNIGDNDFSFRKKELRLVDSKNIPEEKRNNNLNLARPLNLKEFIGQEQLKSSLRV
CEEECCCCCCCHHHHHHHHHEECCCCCCHHHCCCCCCEECCCCHHHHCCHHHHHHHHHH
AIDASIIRKEPLEHTLLYGQPGLGKTTLAFLIAHELNTKCRIATAPAIERPRDIVGLLLG
HHHHHHHHHCCCHHHEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHC
LKEGEVLFIDEIHRLNRLTEELLYSAMEDFRLDLTMGANRGARCRTINLPRFTLIGATTK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCEEEEECHHH
LASISAPLRDRFGISQKIEFYTCDELKQIIVNFSRLINLNLEDEASYDLAKISRGTPRIA
HHHCCCCHHHHCCCCCCEEEEEHHHHHHHHHHHHHHEECCCCCCCCCCHHHHCCCCHHHH
LRLLRRVRDYAQVVMKTNTISVNLIKKALNSYQIDEKGLDSLDRHYLSFLNQNNNIPIGL
HHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEH
DSIASGLGDDSSMLEFVVEPYLIKIGFLTRTPRGRLLTALGKKYIDSKDDNF
HHHHCCCCCCHHHHHHHHCCHHEEEEEEECCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA