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The map label for this gene is btuR [C]

Identifier: 123969309

GI number: 123969309

Start: 1509310

End: 1510470

Strand: Reverse

Name: btuR [C]

Synonym: A9601_17771

Alternate gene names: 123969309

Gene position: 1510470-1509310 (Counterclockwise)

Preceding gene: 123969311

Following gene: 123969307

Centisome position: 90.45

GC content: 38.59

Gene sequence:

>1161_bases
TTGACGAATACGAGTAGAAATAGAGGAATTGGAATTGTCACAGCAAGTGACAGTCAAGAGAGATCAAAAGGTCAATTACA
TATTTATGATGGAGAGGGTAAGGGGAAAAGCCAGGCTGCATTGGGAGTAGTTCTCAGGACAATAGGATTAGGAATATGCG
AAAAAAGACAGTCAAGAGTTTTACTTCTAAGATTCTTAAAAGGCCCTGAGAGGCCATATGACGAGGATTCCGCTATAGAG
GCTTTACAAAGAGGCTTTCCTCATTTAATTGACCATGTAAGGACAGGAAGATCTGAATTCTTTACTGCTGACCAAGTGAC
AAGGTTTGATGTTGGTGAGGCCGAAAGAGGTTGGAATATTGCTAAAGGAGCAATTGCTAGTTCTCTTTATTCTGTAGTTG
TACTCGATGAGTTGAATCCAGTTCTTGATTTAGGAATGCTTGATATCAATGAAGTAGTTGATTCTCTGCAAAATCGTCCA
GATGGATTAGAAATAATTATTACTGGAAGGGCAGCCCCGCCCTCTTTGGTAAGAATATCTCAACTCCATTCAGAAATGAG
ACCACGATTGATAGGAAACTCAGCAGAACTAAACAAACAAAGTAGTTCTAGTGGTGGAATTGAGATTTATACAGGCGAAG
GAAAGGGTAAATCCACAAGTGCACTCGGTAAGGCTCTTCAAGCTATCGGTAAAGGAATATCTCAAGATAAAAGTCATAGA
GTTTTAATATTACAGTGGTTAAAAGGTGGAAATGGATATACCGAAGATGCTGCCATAGAAGCTTTGAGAGAGAGTTACCC
TCATTTAGTAGATCATTTGCGTTCAGGCAGAGATGCCATCGTATGGAGAGGTCAGCAACAACCAATTGATTATGTTGAGG
CTGAAAGAGCATGGGAAATTGCTAAAGCTGCTATTTTGTCTGGCTTGTATAAGACGATTATTTTAGATGAATTAAATCCA
ACTGTTGATTTAGAGTTGTTACCTGTGGAATCAATACATCAAACGCTCTTAAAAAAACCAGCAGAGACAGAAGTTGTAAT
TACTGGAAGGTGTAAAAATGAACCTTCATACTTTGAACTGGCTGATGTTTACTCTGAAATGGTTTGTCATAAGCATTATG
CAAATGTGGGAGTTGATTTAAAAAGAGGTGTAGATTACTAA

Upstream 100 bases:

>100_bases
TTTAAAATTCAAATTACCTATGAATAGGTTGAATTTATTATTAAATCTTTAATAATATTCTTATCTATATCTTAGATTAA
ATTTACTAAATTTTGTTCAA

Downstream 100 bases:

>100_bases
CTATTCTTAAAAAATTAATTGCCCAATATTTTTTTTACCTTTTCGATGCCGCCTTCAATAGATCTTGACTTAATTTTGAA
TTTAGATAAGATTCTTGATG

Product: hypothetical protein

Products: Adenosylcobalamin; Phosphate; Diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTNTSRNRGIGIVTASDSQERSKGQLHIYDGEGKGKSQAALGVVLRTIGLGICEKRQSRVLLLRFLKGPERPYDEDSAIE
ALQRGFPHLIDHVRTGRSEFFTADQVTRFDVGEAERGWNIAKGAIASSLYSVVVLDELNPVLDLGMLDINEVVDSLQNRP
DGLEIIITGRAAPPSLVRISQLHSEMRPRLIGNSAELNKQSSSSGGIEIYTGEGKGKSTSALGKALQAIGKGISQDKSHR
VLILQWLKGGNGYTEDAAIEALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIAKAAILSGLYKTIILDELNP
TVDLELLPVESIHQTLLKKPAETEVVITGRCKNEPSYFELADVYSEMVCHKHYANVGVDLKRGVDY

Sequences:

>Translated_386_residues
MTNTSRNRGIGIVTASDSQERSKGQLHIYDGEGKGKSQAALGVVLRTIGLGICEKRQSRVLLLRFLKGPERPYDEDSAIE
ALQRGFPHLIDHVRTGRSEFFTADQVTRFDVGEAERGWNIAKGAIASSLYSVVVLDELNPVLDLGMLDINEVVDSLQNRP
DGLEIIITGRAAPPSLVRISQLHSEMRPRLIGNSAELNKQSSSSGGIEIYTGEGKGKSTSALGKALQAIGKGISQDKSHR
VLILQWLKGGNGYTEDAAIEALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIAKAAILSGLYKTIILDELNP
TVDLELLPVESIHQTLLKKPAETEVVITGRCKNEPSYFELADVYSEMVCHKHYANVGVDLKRGVDY
>Mature_385_residues
TNTSRNRGIGIVTASDSQERSKGQLHIYDGEGKGKSQAALGVVLRTIGLGICEKRQSRVLLLRFLKGPERPYDEDSAIEA
LQRGFPHLIDHVRTGRSEFFTADQVTRFDVGEAERGWNIAKGAIASSLYSVVVLDELNPVLDLGMLDINEVVDSLQNRPD
GLEIIITGRAAPPSLVRISQLHSEMRPRLIGNSAELNKQSSSSGGIEIYTGEGKGKSTSALGKALQAIGKGISQDKSHRV
LILQWLKGGNGYTEDAAIEALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEIAKAAILSGLYKTIILDELNPT
VDLELLPVESIHQTLLKKPAETEVVITGRCKNEPSYFELADVYSEMVCHKHYANVGVDLKRGVDY

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=193, Percent_Identity=31.6062176165803, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17 [C]

Molecular weight: Translated: 42491; Mature: 42360

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTSRNRGIGIVTASDSQERSKGQLHIYDGEGKGKSQAALGVVLRTIGLGICEKRQSRV
CCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLLRFLKGPERPYDEDSAIEALQRGFPHLIDHVRTGRSEFFTADQVTRFDVGEAERGWNI
HHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHEECCCEEECCCCCCCCCCCH
AKGAIASSLYSVVVLDELNPVLDLGMLDINEVVDSLQNRPDGLEIIITGRAAPPSLVRIS
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
QLHSEMRPRLIGNSAELNKQSSSSGGIEIYTGEGKGKSTSALGKALQAIGKGISQDKSHR
HHHHHHCCHHCCCCHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
VLILQWLKGGNGYTEDAAIEALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEI
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
AKAAILSGLYKTIILDELNPTVDLELLPVESIHQTLLKKPAETEVVITGRCKNEPSYFEL
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHH
ADVYSEMVCHKHYANVGVDLKRGVDY
HHHHHHHHHHHHHHCCCCCHHCCCCC
>Mature Secondary Structure 
TNTSRNRGIGIVTASDSQERSKGQLHIYDGEGKGKSQAALGVVLRTIGLGICEKRQSRV
CCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLLRFLKGPERPYDEDSAIEALQRGFPHLIDHVRTGRSEFFTADQVTRFDVGEAERGWNI
HHHHHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHEECCCEEECCCCCCCCCCCH
AKGAIASSLYSVVVLDELNPVLDLGMLDINEVVDSLQNRPDGLEIIITGRAAPPSLVRIS
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
QLHSEMRPRLIGNSAELNKQSSSSGGIEIYTGEGKGKSTSALGKALQAIGKGISQDKSHR
HHHHHHCCHHCCCCHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCC
VLILQWLKGGNGYTEDAAIEALRESYPHLVDHLRSGRDAIVWRGQQQPIDYVEAERAWEI
EEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHH
AKAAILSGLYKTIILDELNPTVDLELLPVESIHQTLLKKPAETEVVITGRCKNEPSYFEL
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHH
ADVYSEMVCHKHYANVGVDLKRGVDY
HHHHHHHHHHHHHHCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Cob(I)alamin; H2O [C]

Specific reaction: ATP + Cob(I)alamin + H2O <==> Adenosylcobalamin + Phosphate + Diphosphate [C]

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]