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The map label for this gene is alr [H]

Identifier: 123969267

GI number: 123969267

Start: 1480601

End: 1481800

Strand: Reverse

Name: alr [H]

Synonym: A9601_17351

Alternate gene names: 123969267

Gene position: 1481800-1480601 (Counterclockwise)

Preceding gene: 123969269

Following gene: 123969266

Centisome position: 88.74

GC content: 31.25

Gene sequence:

>1200_bases
ATGCAAATTCGGCAAACAAATCATGAATTTAATTTTGGAAGTTATCCAACATTTGGACATAATATTGATCCAAAACAAAG
AGCTTGGATTGAAGTAAGAGGTAAAGCACTAGAGACAAATGTCAGGAATTTAAGATCTAAATTAAGTAAAAATTGTCAAT
TTATGGCAGTGGTTAAAGCTGATGGTTATGGACATGATGCCAAAGTAGTTTCTGAATATGCTATTAGGGGTGGAGCTTCT
CAATTAGGCGTTGCCACTCTAAAAGAAGGGGTTAAGCTTCGTTCTTTTGGAGTAAAAAAACCAATTCTTATTCTCGGAAA
TCTATATACAAAAAGGGATTTAATAATATCTTTTAAAAATGATCTGATGCCAACTATTAGTAGTATAAGAGAGTGTTTGA
TTTGCAATAATATCGGGAAGCAATTTGGGTTAAAATTTTCTTTACATCTTAAGGTTGATACTGGAATGTCAAGATTAGGA
TTTGAATATAGTAGATTTATTCAGAACTTTGAGAAAATAAAATCTTTTGAGAATATTTTAATTGAAGGAATATATAGTCA
TTTATCTTCCGCAGATGAAGATAACGCATTAGATCCTAAAAGTATTACACAACTACAAAGACTGAAGTTCAATGAATTAT
TAAAGCAAATTAATCTTGATAGAAATAATGAAATTAAGATTCATTTGGCTAATTCAGCGGCAATGCTTCTTAACAAAGAC
TTTCATTTTAATATGGTACGTGTGGGGCTCTCTATGTATGGATATAGTCCCCTAACAAAAATTGATAAAAACTTATCGCT
TGAACCAGCTTTATTTTTGAAAGTTAAAGTAGCTTTTATTAGGACTATTGAACCTGGTGTAAATGTAAGTTATGGAGGAA
AATTTGTAAGTTGCAGAAAAACTAAATTAGCTGTCTTAAGTATTGGTTATGCAGATGGAGTTCCGAGAAATCTTTCAGGC
AAGATAAAAGTTATTTACAAAAATAAACTTTACCCCCAAGTTGGATCTATAACAATGGATCAAATGATGGTGGACATAAC
AGGTTCAAATGAAATTAAAGTTGGTAGTACTATGATTTTACTAGGATCTGATGGAGACAAAACTATTACTCCTATTGATT
GGGCAAAAGAATCCGATACTATTCCATGGGAAATTCTTTGTTCTTTCAAAAATAGATTGCCAAGAGTTCAAGTTGATTAG

Upstream 100 bases:

>100_bases
TAAGAAGCATTTAAAACTAGAGTCTGGCTCATGCCAAAATACAATTTACATGTCATGCTAACTGTATATTTCAATAAGCG
CATTTAATTATGCAGAGTTA

Downstream 100 bases:

>100_bases
ACATTTCGATTAAATAAATAATTTTGAATGTTTGCAGAAAAATTGATAATCTATAAGAACTGGAGAGGTGGCTGAGTGGT
TGAAAGCGGCTCCCTGCTAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MQIRQTNHEFNFGSYPTFGHNIDPKQRAWIEVRGKALETNVRNLRSKLSKNCQFMAVVKADGYGHDAKVVSEYAIRGGAS
QLGVATLKEGVKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLICNNIGKQFGLKFSLHLKVDTGMSRLG
FEYSRFIQNFEKIKSFENILIEGIYSHLSSADEDNALDPKSITQLQRLKFNELLKQINLDRNNEIKIHLANSAAMLLNKD
FHFNMVRVGLSMYGYSPLTKIDKNLSLEPALFLKVKVAFIRTIEPGVNVSYGGKFVSCRKTKLAVLSIGYADGVPRNLSG
KIKVIYKNKLYPQVGSITMDQMMVDITGSNEIKVGSTMILLGSDGDKTITPIDWAKESDTIPWEILCSFKNRLPRVQVD

Sequences:

>Translated_399_residues
MQIRQTNHEFNFGSYPTFGHNIDPKQRAWIEVRGKALETNVRNLRSKLSKNCQFMAVVKADGYGHDAKVVSEYAIRGGAS
QLGVATLKEGVKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLICNNIGKQFGLKFSLHLKVDTGMSRLG
FEYSRFIQNFEKIKSFENILIEGIYSHLSSADEDNALDPKSITQLQRLKFNELLKQINLDRNNEIKIHLANSAAMLLNKD
FHFNMVRVGLSMYGYSPLTKIDKNLSLEPALFLKVKVAFIRTIEPGVNVSYGGKFVSCRKTKLAVLSIGYADGVPRNLSG
KIKVIYKNKLYPQVGSITMDQMMVDITGSNEIKVGSTMILLGSDGDKTITPIDWAKESDTIPWEILCSFKNRLPRVQVD
>Mature_399_residues
MQIRQTNHEFNFGSYPTFGHNIDPKQRAWIEVRGKALETNVRNLRSKLSKNCQFMAVVKADGYGHDAKVVSEYAIRGGAS
QLGVATLKEGVKLRSFGVKKPILILGNLYTKRDLIISFKNDLMPTISSIRECLICNNIGKQFGLKFSLHLKVDTGMSRLG
FEYSRFIQNFEKIKSFENILIEGIYSHLSSADEDNALDPKSITQLQRLKFNELLKQINLDRNNEIKIHLANSAAMLLNKD
FHFNMVRVGLSMYGYSPLTKIDKNLSLEPALFLKVKVAFIRTIEPGVNVSYGGKFVSCRKTKLAVLSIGYADGVPRNLSG
KIKVIYKNKLYPQVGSITMDQMMVDITGSNEIKVGSTMILLGSDGDKTITPIDWAKESDTIPWEILCSFKNRLPRVQVD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=366, Percent_Identity=26.5027322404372, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1790487, Length=352, Percent_Identity=30.6818181818182, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 44912; Mature: 44912

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIRQTNHEFNFGSYPTFGHNIDPKQRAWIEVRGKALETNVRNLRSKLSKNCQFMAVVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSEYAIRGGASQLGVATLKEGVKLRSFGVKKPILILGNLYTKRDLIISFKN
CCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCEEEEEECH
DLMPTISSIRECLICNNIGKQFGLKFSLHLKVDTGMSRLGFEYSRFIQNFEKIKSFENIL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHH
IEGIYSHLSSADEDNALDPKSITQLQRLKFNELLKQINLDRNNEIKIHLANSAAMLLNKD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
FHFNMVRVGLSMYGYSPLTKIDKNLSLEPALFLKVKVAFIRTIEPGVNVSYGGKFVSCRK
CCEEHHEEHHHHHCCCCHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCEECCCEEEEECC
TKLAVLSIGYADGVPRNLSGKIKVIYKNKLYPQVGSITMDQMMVDITGSNEIKVGSTMIL
CEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEHEEEEECCCCEEEECEEEEE
LGSDGDKTITPIDWAKESDTIPWEILCSFKNRLPRVQVD
EECCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MQIRQTNHEFNFGSYPTFGHNIDPKQRAWIEVRGKALETNVRNLRSKLSKNCQFMAVVKA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEE
DGYGHDAKVVSEYAIRGGASQLGVATLKEGVKLRSFGVKKPILILGNLYTKRDLIISFKN
CCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCEEEEEECH
DLMPTISSIRECLICNNIGKQFGLKFSLHLKVDTGMSRLGFEYSRFIQNFEKIKSFENIL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCHHHCHHHHHHHHHHHHHHHHHHHH
IEGIYSHLSSADEDNALDPKSITQLQRLKFNELLKQINLDRNNEIKIHLANSAAMLLNKD
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
FHFNMVRVGLSMYGYSPLTKIDKNLSLEPALFLKVKVAFIRTIEPGVNVSYGGKFVSCRK
CCEEHHEEHHHHHCCCCHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCEECCCEEEEECC
TKLAVLSIGYADGVPRNLSGKIKVIYKNKLYPQVGSITMDQMMVDITGSNEIKVGSTMIL
CEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCEEEEHEEEEECCCCEEEECEEEEE
LGSDGDKTITPIDWAKESDTIPWEILCSFKNRLPRVQVD
EECCCCCEECCCCCCCCCCCCCHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]