Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 123969185

GI number: 123969185

Start: 1397246

End: 1398763

Strand: Reverse

Name: atpA [H]

Synonym: A9601_16531

Alternate gene names: 123969185

Gene position: 1398763-1397246 (Counterclockwise)

Preceding gene: 123969186

Following gene: 123969184

Centisome position: 83.76

GC content: 38.21

Gene sequence:

>1518_bases
ATGGTATCTATACGCCCTGATGAAATCAGTTCAATCTTAAAACAACAAATAACTGATTATGACCAATCTGTAAGTGTTAG
CAATGTAGGAACTGTTCTGCAAATCGGTGATGGCATTGCAAGAATATATGGCTTAGATCAGGTCATGGCAGGTGAGTTGT
TGGAATTTGAGGATGGTACCGAAGGTATAGCTTTAAATCTTGAAGATGATAATGTTGGGGCCGTTTTAATGGGAGAGGCA
CTTGGTGTCCAAGAAGGAAGTAACGTTAAGTCCACAGGTAAAATCGCATCTGTTCCAGTTGGTGAAGCAATGCAGGGGAG
AGTTGTTAACCCTCTCGGACAACCAATAGATGGGAAAGGGGAAATTCCAACAAGTGATACAAGATTGATTGAAGAAATGG
CGCCTGGAATAATCAAAAGAAGATCAGTTCATGAACCAATGCAAACTGGTATCACATCTATTGATGCAATGATTCCTGTT
GGAAGAGGTCAAAGAGAATTAATTATTGGCGATAGACAAACTGGAAAATCTGCGATTGCTATCGATACAATTATCAACCA
AAAAGGTCAAGATGTAGTTTGTGTATACGTAGCTATTGGTCAGAAGTCAGCATCAGTAGCAAATATCGTAGAGGTTTTAA
GAGAGAGAGGAGCTCTAGATTACACCGTTGTAGTTAGTGCAGGAGCTTCAGAACCAGCTGCTTTACAGTACTTAGCACCT
TATACTGGTGCAGCAATTGCTGAGCATTTTATGTATCAGGGTAAAGCAACACTTGTTATTTATGATGATCTAACAAAACA
AGCTCAGGCTTACAGACAAATGTCTCTTCTTTTAAAAAGACCACCAGGAAGAGAGGCTTATCCTGGAGACGTGTTCTACT
TGCACAGTAGATTACTAGAAAGAGCAGCAAAACTTTCTGATGCAATGGGCGGGGGTTCTATGACAGCTCTTCCAATTATT
GAAACTCAGGCAGGAGACGTTTCGGCTTACATTCCAACTAATGTTATTTCAATTACGGATGGACAAATATTCTTGAGTGC
AGATTTATTTAACTCAGGATTAAGACCAGCTATTAATGTTGGTATATCTGTTAGTCGTGTTGGAGGAGCAGCTCAGACAA
AAGCAATTAAAAAAATTGCAGGAACTTTAAAATTAGAACTCGCACAGTTTGATGAACTAGCTGCTTTTTCTCAATTTGCA
TCTGATCTTGATGAAGCAACTCAGCAACAACTTGAAAGAGGCAAAAGACTAAGAGAGCTATTAAAGCAACCTCAATTCTC
TCCTCTAAACCTTGCAGAACAAGTTGCAGTTGTTTATGCAGGAGTAAAAGGTCTTATTGATGAGGTTCCTGTTGAAGATG
TTACTAAATTTGCAACTGAACTTAGGGAATACCTAAAATTAAATAAATCAGAATTTATAGAAGAGATTCTTAAAGAAAAG
AAACTAAATGATGGATTAGAAGCGACACTAAAAGAGGTGATAAATGAAGTTAAATCATCAATGCTTGCCACAGTTTAA

Upstream 100 bases:

>100_bases
GGATCAAAAGTAATTGATGCTTCCCTTGCTTCACAAATTAGAAAACTTGGCTTAACTCTTTCCAAGTAACTTTTAAATCA
ACCTTAAATTCTTAAAATCC

Downstream 100 bases:

>100_bases
ATTTATTTAAGGAGATACCATGGCAAATCTTAAAGAGATTAGAGATCGAATCGTTTCTGTTAAAAACACAAGAAAAATAA
CTGAGGCAATGAGACTTGTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKSEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV

Sequences:

>Translated_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKSEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV
>Mature_505_residues
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGTEGIALNLEDDNVGAVLMGEA
LGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKGEIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPV
GRGQRELIIGDRQTGKSAIAIDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLERAAKLSDAMGGGSMTALPII
ETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQQQLERGKRLRELLKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKSEFIEEILKEK
KLNDGLEATLKEVINEVKSSMLATV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=496, Percent_Identity=60.2822580645161, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI4757810, Length=496, Percent_Identity=60.2822580645161, Blast_Score=595, Evalue=1e-170,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=29.6666666666667, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913426, Length=299, Percent_Identity=29.0969899665552, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI32189394, Length=407, Percent_Identity=24.0786240786241, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=54.1666666666667, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1790170, Length=418, Percent_Identity=24.8803827751196, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788251, Length=336, Percent_Identity=29.4642857142857, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=495, Percent_Identity=59.3939393939394, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988080, Length=495, Percent_Identity=59.3939393939394, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988074, Length=495, Percent_Identity=56.1616161616162, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17570191, Length=292, Percent_Identity=29.1095890410959, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=27.7027027027027, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=431, Percent_Identity=23.8979118329466, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=43.5897435897436, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=495, Percent_Identity=58.1818181818182, Blast_Score=582, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319603, Length=299, Percent_Identity=29.0969899665552, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=395, Percent_Identity=25.8227848101266, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=59.2079207920792, Blast_Score=600, Evalue=1e-172,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=28.9115646258503, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24638766, Length=407, Percent_Identity=24.8157248157248, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28574560, Length=400, Percent_Identity=26, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54293; Mature: 54293

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKSEFIEEILKEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVINEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIRPDEISSILKQQITDYDQSVSVSNVGTVLQIGDGIARIYGLDQVMAGELLEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHEECCCHHHHHHHHHHHHHHHHHCCCCCC
EGIALNLEDDNVGAVLMGEALGVQEGSNVKSTGKIASVPVGEAMQGRVVNPLGQPIDGKG
CCEEEEECCCCCCEEEECCHHCCCCCCCCCCCCCEECCCCCCHHCCCCCCCCCCCCCCCC
EIPTSDTRLIEEMAPGIIKRRSVHEPMQTGITSIDAMIPVGRGQRELIIGDRQTGKSAIA
CCCCHHHHHHHHHCCHHHHHHHHCCHHHHCHHHHHHHCCCCCCCCEEEECCCCCCCCEEE
IDTIINQKGQDVVCVYVAIGQKSASVANIVEVLRERGALDYTVVVSAGASEPAALQYLAP
HHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLKRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSDAMGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSADLFNSGLRPAINV
HHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEEEHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQQQLERGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQFSPLNLAEQVAVVYAGVKGLIDEVPVEDVTKFATELREYLKLNKSEFIEEILKEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLNDGLEATLKEVINEVKSSMLATV
CCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA