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The map label for this gene is melB [C]

Identifier: 123969055

GI number: 123969055

Start: 1304362

End: 1305708

Strand: Direct

Name: melB [C]

Synonym: A9601_15231

Alternate gene names: 123969055

Gene position: 1304362-1305708 (Clockwise)

Preceding gene: 123969054

Following gene: 123969056

Centisome position: 78.11

GC content: 34.82

Gene sequence:

>1347_bases
ATGTTGTCTTATGGGCTAGGAGATGCAGGTACAGGTTTAGTCGCTACGCAATTTGGTTTTTTTCTGTTCAAATTCTTTAT
TTCTGCTGGTTTACCAGTAATAATTGCAGGTTCATTATTAATGTTAATAAAGATATGGGATGCAGTAAATGATCCGTTGA
TTGGATGGTTAAGTGATCGTACTAAATCCAGATGGGGGCCTAGAATCCCTTGGATGGTAGCAGCATCTGTTCCGCTTGGT
TTATCTTTAGCTGCGATATGGTGGACACCCACTGGTTCCGTGCTAACCAAGACTATTTACTACGCCATAATTTCTATAAT
CGTAATGACCGCTTATACTAGTATTAATCTTCCTTTTGCAGCTTTATCTACTGAAATTTCTGAAAAAACAGCAATAAGAA
CAAGATTAAACGCCTCTAGATTTACTGGCTCAATAATTGCAGGACTAACTGGTTTAATCATTGCAGGAGTTGTATTGGGT
TCTGAAGGATCAGCAAATAATGAATATTTTTTAATGGGTAAAATAAGCGGATGTATTGCAGTTGCTGCAACATTAATTTC
TTGTTGGGGATTGGCTCCATTCGCGAAAAAAGCAAGAAGGCCTTCAGGGAAAGTTGAAGCAATAACACTTCAATTCAAAA
GGATCTTCAGAAATAAAAAATTTCTAAAAGTTATTACTCTTTATATTCTTCTCTGGTGCGCCTTACAATTGATGCAAACA
GTAGCGTTAATCTATGTAGAGGATGTACTTAATGTTCCAACATACATTGCGAAGTGGATCCCGATACCTTTCCAAATTAG
CGCTTTAGTGGGTCTACAAATATGGACCAGAGTATCAAATAAATTGAACAGAATTTCAGCTTTAAACTATGGAGCGATTT
TATGGATTATTTCATGTACGGCAGCTTTATTTTTACCTTCTTTATCAAAAATTTCAGGAGTTGGAGATAGTTTATTCCTA
AATACCAGCAATATATTTCTGTTCATTCTTTTAATTTTCATAATCTGTCTTATTGGCATTGGGGCTTCAACCGCTTTTCT
TATCCCTTGGTCACTACTTCCTGATGCAATAGACGAAGACCCAGAAAAACCAGCAGGATTATATACCGCTTGGATGGTAC
TTATTCAGAAGATTGGTATCGCGTTTAGTGTTCAATTATTAGGATTTTTATTGTATTTATCAGGTTATCAATCATGCTTT
GTTGATAAAGATAGTCTAAATATTATTGAACAATGCTACTCAGCACAATTAACTATTAGATTATGTATTGGTTTTATACC
CTCAATATTGGTAATAATTGGTCTTTTAATAATGAGAAAATGGGATCCAAAATTAATTACAAACTAA

Upstream 100 bases:

>100_bases
AATTACCATTGCAATAATACATTATCAAACAATCAACAAAGTAAAAAGATTGGAAAATTCACACTCGAAAAAAAATATTA
CTAGATCAACAACAAGATTA

Downstream 100 bases:

>100_bases
TATAGAGATATGTATTACCCTAATTTTTTCAAAAGACTTCTAAGCAGCTTAATCATTGGCGGGCAAGCAATTAATTTTAT
CTTTAAGGGTAAAATTTCCA

Product: GPH family sugar transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MLSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVAASVPLG
LSLAAIWWTPTGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARRPSGKVEAITLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VALIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAILWIISCTAALFLPSLSKISGVGDSLFL
NTSNIFLFILLIFIICLIGIGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCF
VDKDSLNIIEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDPKLITN

Sequences:

>Translated_448_residues
MLSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVAASVPLG
LSLAAIWWTPTGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARRPSGKVEAITLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VALIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAILWIISCTAALFLPSLSKISGVGDSLFL
NTSNIFLFILLIFIICLIGIGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCF
VDKDSLNIIEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDPKLITN
>Mature_448_residues
MLSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDRTKSRWGPRIPWMVAASVPLG
LSLAAIWWTPTGSVLTKTIYYAIISIIVMTAYTSINLPFAALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLG
SEGSANNEYFLMGKISGCIAVAATLISCWGLAPFAKKARRPSGKVEAITLQFKRIFRNKKFLKVITLYILLWCALQLMQT
VALIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAILWIISCTAALFLPSLSKISGVGDSLFL
NTSNIFLFILLIFIICLIGIGASTAFLIPWSLLPDAIDEDPEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCF
VDKDSLNIIEQCYSAQLTIRLCIGFIPSILVIIGLLIMRKWDPKLITN

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=439, Percent_Identity=22.7790432801822, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI211063479, Length=452, Percent_Identity=22.787610619469, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI122937339, Length=462, Percent_Identity=19.6969696969697, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082306, Length=414, Percent_Identity=22.9468599033816, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786466, Length=412, Percent_Identity=24.2718446601942, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790561, Length=323, Percent_Identity=24.7678018575851, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994989, Length=414, Percent_Identity=22.9468599033816, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787902, Length=157, Percent_Identity=25.4777070063694, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49115; Mature: 49115

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
TKSRWGPRIPWMVAASVPLGLSLAAIWWTPTGSVLTKTIYYAIISIIVMTAYTSINLPFA
HHCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLGSEGSANNEYFLMGKISGCIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHH
VAATLISCWGLAPFAKKARRPSGKVEAITLQFKRIFRNKKFLKVITLYILLWCALQLMQT
HHHHHHHHHCCCHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VALIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAILWIISCT
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALFLPSLSKISGVGDSLFLNTSNIFLFILLIFIICLIGIGASTAFLIPWSLLPDAIDED
HHHHHCCHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHCCHHHCCC
PEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCFVDKDSLNIIEQCYSAQLTIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHH
LCIGFIPSILVIIGLLIMRKWDPKLITN
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLSYGLGDAGTGLVATQFGFFLFKFFISAGLPVIIAGSLLMLIKIWDAVNDPLIGWLSDR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
TKSRWGPRIPWMVAASVPLGLSLAAIWWTPTGSVLTKTIYYAIISIIVMTAYTSINLPFA
HHCCCCCCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALSTEISEKTAIRTRLNASRFTGSIIAGLTGLIIAGVVLGSEGSANNEYFLMGKISGCIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHH
VAATLISCWGLAPFAKKARRPSGKVEAITLQFKRIFRNKKFLKVITLYILLWCALQLMQT
HHHHHHHHHCCCHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VALIYVEDVLNVPTYIAKWIPIPFQISALVGLQIWTRVSNKLNRISALNYGAILWIISCT
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AALFLPSLSKISGVGDSLFLNTSNIFLFILLIFIICLIGIGASTAFLIPWSLLPDAIDED
HHHHHCCHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHCCHHHCCC
PEKPAGLYTAWMVLIQKIGIAFSVQLLGFLLYLSGYQSCFVDKDSLNIIEQCYSAQLTIR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHH
LCIGFIPSILVIIGLLIMRKWDPKLITN
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]