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The map label for this gene is era [H]

Identifier: 123969012

GI number: 123969012

Start: 1261046

End: 1261957

Strand: Reverse

Name: era [H]

Synonym: A9601_14801

Alternate gene names: 123969012

Gene position: 1261957-1261046 (Counterclockwise)

Preceding gene: 123969014

Following gene: 123969011

Centisome position: 75.57

GC content: 31.8

Gene sequence:

>912_bases
TTGACCAATTATAGATCTGGGTTTGTAACTTTACTAGGAAGGCCAAATGTGGGTAAATCTACTTTAATAAATAAATTGAT
TGGCGAAAAAATAACAATTACTTCTCCAATAGCGCAAACTACAAGAAATAAATTAAAAGGAATACTTACTACAAAAGATG
GGCAAATAATTTTTGTCGATACTCCTGGTGTGCATAAACCTCATCATCGACTTGGAGAGATATTAGTAAAAAACGCAAAA
TCGGCAATTAATGGAGTTGATATGGTAATTTTTGTAATTGATTCAAGTGAAGAACCTGGAAGAGGTGATGAATATATTTT
GAACTTTTTAATCGCAAATAAAACTGAGTTTATTGTTGCATTAAATAAGTGGGATTTGGTTAATAAAGAATTTAGGAATT
TACGATTAGATCAATATAGAAGATTTTTTGGAATTTATAGAAACTTTCAAGTTGTAAGTGCTTCTCAAGGAGAAGGATGT
TCTGAACTAATAGATATGGCTCTTAATTTTCTTCCTGAAGGACCAAAACTTTATGGCGAAGAGACGATTTGCGACCAACC
GTTAGATAACTTATTATCTGATTTAGTAAGAGAACAGGTATTAAAAAATACAAGAGAAGAAGTACCTCATAGTGTCGCAG
TAAAGATAGAAAAGAGAGAGGAAATGAAAAGAAAAAATGGCAAAGTTTTTACAGCCATTTTGGCTACTATTATTGTTGAA
AGGTCCACTCAAAAAGGCATTCTTATCGGAAAGAAAGGTTCAATGTTAAAAATGATTGGTCAGTCAGCAAGATCAAATAT
GTCAAAATTAATTGATGGTCCAGTTCACCTAGAGTTGTTTGTGAAAGTTGTTCCTAATTGGAGAAAAAAAGAATCAAGGT
TAATTGAGTTTGGTTATGAGGAAGAATTCTAG

Upstream 100 bases:

>100_bases
GCGGATATGTTTATTGCTTGCGTGAACGAAGCTTCTTTTAAATTTATGGTTTTTTTTTTCATTTTTGATCAGAATTTTAT
TATTGATGCATTAAAAGTCT

Downstream 100 bases:

>100_bases
ATGAGTGGTTTTAATTTTGATGTAATTACATTGTTCCCTAAAGCTTTTGAATTAATAAATAATTTAGGGGTCATAACAAG
AGCTCTAGATAAGAAGTTAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTNYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTKDGQIIFVDTPGVHKPHHRLGEILVKNAK
SAINGVDMVIFVIDSSEEPGRGDEYILNFLIANKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGIYRNFQVVSASQGEGC
SELIDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKREEMKRKNGKVFTAILATIIVE
RSTQKGILIGKKGSMLKMIGQSARSNMSKLIDGPVHLELFVKVVPNWRKKESRLIEFGYEEEF

Sequences:

>Translated_303_residues
MTNYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTKDGQIIFVDTPGVHKPHHRLGEILVKNAK
SAINGVDMVIFVIDSSEEPGRGDEYILNFLIANKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGIYRNFQVVSASQGEGC
SELIDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKREEMKRKNGKVFTAILATIIVE
RSTQKGILIGKKGSMLKMIGQSARSNMSKLIDGPVHLELFVKVVPNWRKKESRLIEFGYEEEF
>Mature_302_residues
TNYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTKDGQIIFVDTPGVHKPHHRLGEILVKNAKS
AINGVDMVIFVIDSSEEPGRGDEYILNFLIANKTEFIVALNKWDLVNKEFRNLRLDQYRRFFGIYRNFQVVSASQGEGCS
ELIDMALNFLPEGPKLYGEETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKREEMKRKNGKVFTAILATIIVER
STQKGILIGKKGSMLKMIGQSARSNMSKLIDGPVHLELFVKVVPNWRKKESRLIEFGYEEEF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=332, Percent_Identity=25.3012048192771, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1788919, Length=302, Percent_Identity=37.7483443708609, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI87082120, Length=164, Percent_Identity=29.8780487804878, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=161, Percent_Identity=31.055900621118, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34319; Mature: 34188

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTKDGQIIFVD
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHCEEEEECCCEEEEEE
TPGVHKPHHRLGEILVKNAKSAINGVDMVIFVIDSSEEPGRGDEYILNFLIANKTEFIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEE
LNKWDLVNKEFRNLRLDQYRRFFGIYRNFQVVSASQGEGCSELIDMALNFLPEGPKLYGE
ECCCHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKREEMKRKNGKVFTAILATIIVE
CHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHH
RSTQKGILIGKKGSMLKMIGQSARSNMSKLIDGPVHLELFVKVVPNWRKKESRLIEFGYE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCHHHHHHHEECCCC
EEF
CCC
>Mature Secondary Structure 
TNYRSGFVTLLGRPNVGKSTLINKLIGEKITITSPIAQTTRNKLKGILTTKDGQIIFVD
CCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHCEEEEECCCEEEEEE
TPGVHKPHHRLGEILVKNAKSAINGVDMVIFVIDSSEEPGRGDEYILNFLIANKTEFIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEE
LNKWDLVNKEFRNLRLDQYRRFFGIYRNFQVVSASQGEGCSELIDMALNFLPEGPKLYGE
ECCCHHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCC
ETICDQPLDNLLSDLVREQVLKNTREEVPHSVAVKIEKREEMKRKNGKVFTAILATIIVE
CHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHHH
RSTQKGILIGKKGSMLKMIGQSARSNMSKLIDGPVHLELFVKVVPNWRKKESRLIEFGYE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEECCCCCHHHHHHHEECCCC
EEF
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA