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The map label for this gene is galE [H]

Identifier: 123968960

GI number: 123968960

Start: 1199934

End: 1201001

Strand: Direct

Name: galE [H]

Synonym: A9601_14271

Alternate gene names: 123968960

Gene position: 1199934-1201001 (Clockwise)

Preceding gene: 123968954

Following gene: 123968961

Centisome position: 71.86

GC content: 29.21

Gene sequence:

>1068_bases
ATGAAAACTGTTCTTACCACAGGAGGACTTGGATATATAGGAAGTCACACGGTAATTGCACTTATAAATCGGGGTTTTAA
TGTTTTGATTATTGATTCATTAATAAATTCTAAGTCGGAAACGTTTAATAATATTGAAAAAATTTTATTTAATGAGATGG
GTGAAATTAAAGAAAAATTATTTTTTAGGAAAGGAGATTTAAGGAACAAATTATGGCTTGAAAATATTTTTCAGGAATTT
AATGATAAAAAACAACCTATCGAGGCCGTCATTCACTTCGCAGGTTTAAAATCTATAGGAGAATCTATATTAAATCCCTT
AAATTACTATGATGTAAATCTCAACACTACTTTATGTCTCCTTTCAGTAATGTCTAAATTTAAATGCTTTAAATTGATAT
TTAGTAGTAGCGCAACTGTTTATAAAATTGATAAAAATGAAAAGATATCAGAAAATGGAATCCTTTCACCTCTTAATCCA
TATGGAAATACAAAATTAAGTAACGAAAAAATAATCGAAGACGTTTTTAAAAGCGACGATAAAAGATGGAAAATAGCTAA
CTTGAGGTATTTCAATCCTTGTGGAGCTCATGATTCAGGAATAATTGGAGAAAATCCCTTAATAAATCATTCAAATATAT
TTCCTACAATTTTAAGGGTAATTAATAGAGAGATTGAAAAACTTCCTATTTACGGATCCGATTGGCCTACTAAAGATGGG
ACATGTATTAGAGACTATATTCATGTAATGGATTTAGCAGAAGCTCATTTAGCTGCACTTATTTATTTATATGAAAATGA
GCCGACTTACCTTAATCTCAATATTGGAACGGGTACAGGTATAAGTGTACTAGAACTTATTAAGACCTTTAGCAATGTAA
ATAATTGTCAAATTCCATATTACTTTACTGAAAAAAGAAAAGGTGATGCTGCTTTCGTTGTTGCGAATAATTCTTTAGTT
ATTCAAACTTTAAAGTGGGAACCTAAGAGAAACCTAAAAGATATTTGCAAAGACTCATGGCGTTGGTTTATCAAAAGTAA
AGAAGGAAGTAATTTTAAAAATAATTGA

Upstream 100 bases:

>100_bases
TAATTATTTCTCAAAGTATTTTATTAATTAATACTTATAAATATATAAAAAATAAATGACTTTAAATGATAATTTAGAAA
TTAGATCTTATAACTTCTGA

Downstream 100 bases:

>100_bases
TTTTTTTCTTTAAGAACGACTAGATGTAATTCATAAAATATTTTTGGAATGTTCAAGATATAAATTTTAGAAGAGCCTAA
AAAAAATACAGCAACTTATT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKTVLTTGGLGYIGSHTVIALINRGFNVLIIDSLINSKSETFNNIEKILFNEMGEIKEKLFFRKGDLRNKLWLENIFQEF
NDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLNTTLCLLSVMSKFKCFKLIFSSSATVYKIDKNEKISENGILSPLNP
YGNTKLSNEKIIEDVFKSDDKRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDG
TCIRDYIHVMDLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPYYFTEKRKGDAAFVVANNSLV
IQTLKWEPKRNLKDICKDSWRWFIKSKEGSNFKNN

Sequences:

>Translated_355_residues
MKTVLTTGGLGYIGSHTVIALINRGFNVLIIDSLINSKSETFNNIEKILFNEMGEIKEKLFFRKGDLRNKLWLENIFQEF
NDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLNTTLCLLSVMSKFKCFKLIFSSSATVYKIDKNEKISENGILSPLNP
YGNTKLSNEKIIEDVFKSDDKRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDG
TCIRDYIHVMDLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPYYFTEKRKGDAAFVVANNSLV
IQTLKWEPKRNLKDICKDSWRWFIKSKEGSNFKNN
>Mature_355_residues
MKTVLTTGGLGYIGSHTVIALINRGFNVLIIDSLINSKSETFNNIEKILFNEMGEIKEKLFFRKGDLRNKLWLENIFQEF
NDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLNTTLCLLSVMSKFKCFKLIFSSSATVYKIDKNEKISENGILSPLNP
YGNTKLSNEKIIEDVFKSDDKRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDG
TCIRDYIHVMDLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPYYFTEKRKGDAAFVVANNSLV
IQTLKWEPKRNLKDICKDSWRWFIKSKEGSNFKNN

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=353, Percent_Identity=39.6600566572238, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI56118217, Length=353, Percent_Identity=39.6600566572238, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI189083684, Length=353, Percent_Identity=39.6600566572238, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI7657641, Length=350, Percent_Identity=23.1428571428571, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786974, Length=350, Percent_Identity=41.1428571428571, Blast_Score=257, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71982038, Length=354, Percent_Identity=38.135593220339, Blast_Score=227, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI71982035, Length=351, Percent_Identity=37.8917378917379, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6319493, Length=359, Percent_Identity=41.7827298050139, Blast_Score=275, Evalue=1e-74,
Organism=Drosophila melanogaster, GI19923002, Length=350, Percent_Identity=41.1428571428571, Blast_Score=265, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40570; Mature: 40570

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLTTGGLGYIGSHTVIALINRGFNVLIIDSLINSKSETFNNIEKILFNEMGEIKEKL
CCEEEECCCCCCCCCHHEEEEHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FFRKGDLRNKLWLENIFQEFNDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLNTTLCL
HHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
LSVMSKFKCFKLIFSSSATVYKIDKNEKISENGILSPLNPYGNTKLSNEKIIEDVFKSDD
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
KRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDG
CEEEEECEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TCIRDYIHVMDLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPY
HHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCE
YFTEKRKGDAAFVVANNSLVIQTLKWEPKRNLKDICKDSWRWFIKSKEGSNFKNN
EECCCCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MKTVLTTGGLGYIGSHTVIALINRGFNVLIIDSLINSKSETFNNIEKILFNEMGEIKEKL
CCEEEECCCCCCCCCHHEEEEHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FFRKGDLRNKLWLENIFQEFNDKKQPIEAVIHFAGLKSIGESILNPLNYYDVNLNTTLCL
HHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHH
LSVMSKFKCFKLIFSSSATVYKIDKNEKISENGILSPLNPYGNTKLSNEKIIEDVFKSDD
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
KRWKIANLRYFNPCGAHDSGIIGENPLINHSNIFPTILRVINREIEKLPIYGSDWPTKDG
CEEEEECEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TCIRDYIHVMDLAEAHLAALIYLYENEPTYLNLNIGTGTGISVLELIKTFSNVNNCQIPY
HHHHHHHHHHHHHHHHHEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCE
YFTEKRKGDAAFVVANNSLVIQTLKWEPKRNLKDICKDSWRWFIKSKEGSNFKNN
EECCCCCCCEEEEEECCCEEEEEECCCCCCCHHHHHHHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]