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The map label for this gene is tldD [C]

Identifier: 123968559

GI number: 123968559

Start: 885703

End: 887127

Strand: Direct

Name: tldD [C]

Synonym: A9601_10261

Alternate gene names: 123968559

Gene position: 885703-887127 (Clockwise)

Preceding gene: 123968558

Following gene: 123968560

Centisome position: 53.04

GC content: 35.72

Gene sequence:

>1425_bases
ATGCTTTCGTCACAAATCAAATCAAATGAAATCGTTTTTGGTAGTTGCAATAAAGATTTATTAGAAGAAATTATTTTCTA
CGGGATGGAGCTTGGGGCCGATTTTGTAGAAATATTTGTAGAGAATACTGATAATTCTAGTGTGCTAGCTGAAGAGGATT
TCATTACAAGTGTAAGTCCATCATTTGGAAAGGGTGCCGGTATTAGAATCTTCAAAGACAAAAAGGACGGATTTGTATGT
ACAAATGACTTAACAAAGCATGGCTTGATGAGATCGGTATCTCAGGCTATTGAGATGTTAGACATAACAGACAACAAAAA
AAGAGGAGTATTTAACGGTTTAGATAAATTCAGGGACTATAGTTTATCCAAAAAAAAATGGATAAATGAAGTTCCATCGA
TTCATGAGATAAGTGAAAAACTATTAGTCAGTACAAAGTCTCTTAAAAAAAATAATAAAATAATAACTAGAAAAGGAAGT
TACTCAAGAAATCTGCAAGAAGTTATCATAGCCTCTAGCGATGGGACCTATGTTTCAGATATTAGGTTGCATCAAACAGT
TGGGCTCAACGTGATTGCTAGTGATGCCCAATATAGATCTAGTGGAAGTAGAAGATTTGGATCTTCAGGAATGCCTCTTG
AATTCAGATTATGGGATCACGAAAAAGCAGCTAATGATGTATTCGAAAGCTCAATGAACATGTTGTATGCAGACTATGTT
GATGCGGGACAAATGCCTGTTGTATTAGCTAATAAATTTGGTGGTGTTATATTCCACGAAGCCTGCGGTCATTTACTTGA
AACTACTCAAATAGAGAGAGGAACAACACCATTTGAGAATAAATTGAATGAAAAAATTGCACATGAATCTGTAACAGCAA
TAGATGAAGGGATTTCAGAAGGATCCTTTGGTTCATTATCAGTAGATGATGAAGGTATGGAACCCGAAAAATCAGTTCTT
ATAAAAGATGGGATTTTAAAAAAATTCATATCGGACAGGGCAGGTGAATTAAGAACTGGCCATAAAAGAACAGGAAGTGG
AAGAAGACAAAACTATTCTTTTGCTGCTGCTTCACGAATGAGAAATACTTATATAGCTAAAGGTGAGCACTCTAAAGAGG
ATTTAATCAATAGTATTAGTGATGGTCTTTACTGCAAATCAATGGGTGGTGGTAGTGTAGGTGCTACCGGACAATTTAAT
TTTGCAGTTGAAGAAGGATATCTTATTAAAAATGGAAAATTAACTAATCCAGTAAAGGGAGCAACTTTGATTGGTGAGGC
CAAAGAAGTTATGCCAAAAATATCAATGTGTGGAAATGACCTCGAATTAGCTCCCGGATTCTGTGGATCCATTAGTGGAA
GTGTCAATGTAACTGTTGGCCAACCTCATATTAAGGTTGATTCAATCACTGTTGGCGGAAGATAG

Upstream 100 bases:

>100_bases
TACCAGTTATTAAGACTATACTTATTAAAACCTCTTGATAGCAAAGATTTCCAACCTTCGATTAGATAATCTTTTATACA
GAGAAGATTAATAGACTCTT

Downstream 100 bases:

>100_bases
GATATGAATTCAAAAGAAATAACAACTCAAATCTCTGAAGCTGCAGATTCTCTAAATCTTAGAAAATGGGATTATGGAGC
AAGCTTTTCTAATGATTATT

Product: putative modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGMELGADFVEIFVENTDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKKDGFVC
TNDLTKHGLMRSVSQAIEMLDITDNKKRGVFNGLDKFRDYSLSKKKWINEVPSIHEISEKLLVSTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNVIASDAQYRSSGSRRFGSSGMPLEFRLWDHEKAANDVFESSMNMLYADYV
DAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR

Sequences:

>Translated_474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGMELGADFVEIFVENTDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKKDGFVC
TNDLTKHGLMRSVSQAIEMLDITDNKKRGVFNGLDKFRDYSLSKKKWINEVPSIHEISEKLLVSTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNVIASDAQYRSSGSRRFGSSGMPLEFRLWDHEKAANDVFESSMNMLYADYV
DAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
>Mature_474_residues
MLSSQIKSNEIVFGSCNKDLLEEIIFYGMELGADFVEIFVENTDNSSVLAEEDFITSVSPSFGKGAGIRIFKDKKDGFVC
TNDLTKHGLMRSVSQAIEMLDITDNKKRGVFNGLDKFRDYSLSKKKWINEVPSIHEISEKLLVSTKSLKKNNKIITRKGS
YSRNLQEVIIASSDGTYVSDIRLHQTVGLNVIASDAQYRSSGSRRFGSSGMPLEFRLWDHEKAANDVFESSMNMLYADYV
DAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEHSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=458, Percent_Identity=31.6593886462882, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1790682, Length=456, Percent_Identity=22.1491228070175, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51805; Mature: 51805

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQIKSNEIVFGSCNKDLLEEIIFYGMELGADFVEIFVENTDNSSVLAEEDFITSVSP
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCHHCCCCC
SFGKGAGIRIFKDKKDGFVCTNDLTKHGLMRSVSQAIEMLDITDNKKRGVFNGLDKFRDY
CCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
SLSKKKWINEVPSIHEISEKLLVSTKSLKKNNKIITRKGSYSRNLQEVIIASSDGTYVSD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNVIASDAQYRSSGSRRFGSSGMPLEFRLWDHEKAANDVFESSMNMLYADYV
EEEEHEECCEEEECCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEHHC
DAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISE
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEECCCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEHSKEDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MLSSQIKSNEIVFGSCNKDLLEEIIFYGMELGADFVEIFVENTDNSSVLAEEDFITSVSP
CCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCHHCCCCC
SFGKGAGIRIFKDKKDGFVCTNDLTKHGLMRSVSQAIEMLDITDNKKRGVFNGLDKFRDY
CCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
SLSKKKWINEVPSIHEISEKLLVSTKSLKKNNKIITRKGSYSRNLQEVIIASSDGTYVSD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEEECCCCCEEEE
IRLHQTVGLNVIASDAQYRSSGSRRFGSSGMPLEFRLWDHEKAANDVFESSMNMLYADYV
EEEEHEECCEEEECCCHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEHHC
DAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGISE
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCEEECCCCCCCCHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEHSKEDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]