Click here to switch to the map view.

The map label for this gene is rnr [C]

Identifier: 123968527

GI number: 123968527

Start: 865243

End: 866427

Strand: Direct

Name: rnr [C]

Synonym: A9601_09941

Alternate gene names: 123968527

Gene position: 865243-866427 (Clockwise)

Preceding gene: 123968526

Following gene: 123968528

Centisome position: 51.81

GC content: 22.7

Gene sequence:

>1185_bases
TTGAAAGATTTAACTAATTTAAAAACATATATTATTGACTCTGATGATCCACATGAGGTTGATGACGCTGTTTCATTAGA
AATAAGAAAAGGAAATAAAAAAAAATTATGGATACATATTAGTAATCCATGCAAACTCTTTTTGCATGAATCTAATATTG
ATTTAAATGCAAGAAAGAGAAATAGCAGTTTATATTTAATTGATCAATATGTCCCAATGCTGCCTAATGATATTCTTGAA
AAGGCAAATCTAGCCCAAAATAAAGTTTCAGAAACTATTAGTGCAGCGATAGAATTCAATGACGATGGATCAATAAATAA
ATATGAAATAACTGAAGCAATAATAAAACCAAAATATCAATTAACATATGAAGATGCAAATGAAATATTAGAAATAGAAC
CCAAAGAAGAAATAGAATTACTTGAGATTAAAAAATTATTAGAAAAAAGTATTAAATTTAGAAAGAAACAAGGAGCAATT
ATTTTTGAAAGTCCTAATAATAAAATTAAATTATATAAGGATAAGATTATACTTACTAAATTAGAGAAGACAATATCACA
AATTATAATTGCAGAATCAATGATATTAATGGGTTATGTAACAAGTTTATTTATAGATAAATATGATTTAGCGGCTGCAT
TTAGGATTCAAAAAATAAACTGCAATCCATCTGAAATACTCAATAGATATAATGATAGTGATATTAAATATATAATATTA
AAACAATATATGGGAAGAAGTTACATAACTACTAAGCCTGGAATTCATGAATCTTTAGGCCTTAAAATGTATGTACAATG
TACATCACCACTAAGAAGATATCTTGATTTGATTATACAAAGGCAAGTCTATAACAAAATTAATAATTACGAAGTTCTTA
GTAAAGATTCAGTCTCTAAGATTATTGATTATTCAAAGAATAGACAATCAGAAAATAATAATATATTTAAAAATGATAAA
TATAAGTATTTAAAATTATTTTTTAAAAATGAAGAAAAAGCTTTTTATAAAATTATATTCGTTAAGTGGATTAATCATAA
AAAAAATATTGCTTTGGTTTATTTTCCAGATTATTCACTAGAAATACTTATTACTCTTTTTGTATCAATAGAAATATACA
GTAATAAAATATATAAAGTTAAATATATTATAAATGATAGTAATCTTTTAGAATTTATTTATTAA

Upstream 100 bases:

>100_bases
TGTAAAGAGAGCCAGAATTGTAGCTCTTTTACCCTTCGTAAATCCTGAAGGATAATTTCATATTTAATATATTTGGCACT
ATAATTAATATTTCAAATAT

Downstream 100 bases:

>100_bases
TAAGATAATCAATATAATGGGTTATTATTAGTTTAAAAAATATCTGTTAGTATAAATATAAAAGCTTTATGACTTTTGTC
ATTACTACACCTTTATACTA

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKDLTNLKTYIIDSDDPHEVDDAVSLEIRKGNKKKLWIHISNPCKLFLHESNIDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELLEIKKLLEKSIKFRKKQGAI
IFESPNNKIKLYKDKIILTKLEKTISQIIIAESMILMGYVTSLFIDKYDLAAAFRIQKINCNPSEILNRYNDSDIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
YKYLKLFFKNEEKAFYKIIFVKWINHKKNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY

Sequences:

>Translated_394_residues
MKDLTNLKTYIIDSDDPHEVDDAVSLEIRKGNKKKLWIHISNPCKLFLHESNIDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELLEIKKLLEKSIKFRKKQGAI
IFESPNNKIKLYKDKIILTKLEKTISQIIIAESMILMGYVTSLFIDKYDLAAAFRIQKINCNPSEILNRYNDSDIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
YKYLKLFFKNEEKAFYKIIFVKWINHKKNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
>Mature_394_residues
MKDLTNLKTYIIDSDDPHEVDDAVSLEIRKGNKKKLWIHISNPCKLFLHESNIDLNARKRNSSLYLIDQYVPMLPNDILE
KANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQLTYEDANEILEIEPKEEIELLEIKKLLEKSIKFRKKQGAI
IFESPNNKIKLYKDKIILTKLEKTISQIIIAESMILMGYVTSLFIDKYDLAAAFRIQKINCNPSEILNRYNDSDIKYIIL
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSKIIDYSKNRQSENNNIFKNDK
YKYLKLFFKNEEKAFYKIIFVKWINHKKNIALVYFPDYSLEILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=328, Percent_Identity=25, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323943, Length=333, Percent_Identity=30.03003003003, Blast_Score=113, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 46428; Mature: 46428

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLTNLKTYIIDSDDPHEVDDAVSLEIRKGNKKKLWIHISNPCKLFLHESNIDLNARKR
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCEEEEEC
NSSLYLIDQYVPMLPNDILEKANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHCCCEE
LTYEDANEILEIEPKEEIELLEIKKLLEKSIKFRKKQGAIIFESPNNKIKLYKDKIILTK
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEHHHH
LEKTISQIIIAESMILMGYVTSLFIDKYDLAAAFRIQKINCNPSEILNRYNDSDIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHCCCCCCEEEEEE
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSK
EHHCCCCEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
IIDYSKNRQSENNNIFKNDKYKYLKLFFKNEEKAFYKIIFVKWINHKKNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEHEEEEEECCEEEEEEEEECCCCEEEECC
>Mature Secondary Structure
MKDLTNLKTYIIDSDDPHEVDDAVSLEIRKGNKKKLWIHISNPCKLFLHESNIDLNARKR
CCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEEECCCCEEEEEC
NSSLYLIDQYVPMLPNDILEKANLAQNKVSETISAAIEFNDDGSINKYEITEAIIKPKYQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEHHHHHHCCCEE
LTYEDANEILEIEPKEEIELLEIKKLLEKSIKFRKKQGAIIFESPNNKIKLYKDKIILTK
EEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEHHHH
LEKTISQIIIAESMILMGYVTSLFIDKYDLAAAFRIQKINCNPSEILNRYNDSDIKYIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHCCCCCCEEEEEE
KQYMGRSYITTKPGIHESLGLKMYVQCTSPLRRYLDLIIQRQVYNKINNYEVLSKDSVSK
EHHCCCCEEECCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHH
IIDYSKNRQSENNNIFKNDKYKYLKLFFKNEEKAFYKIIFVKWINHKKNIALVYFPDYSL
HHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEEECCCCCEEEEEECCCCH
EILITLFVSIEIYSNKIYKVKYIINDSNLLEFIY
HEEEEEHEEEEEECCEEEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]