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The map label for this gene is pgi [H]

Identifier: 123968504

GI number: 123968504

Start: 837779

End: 839362

Strand: Direct

Name: pgi [H]

Synonym: A9601_09711

Alternate gene names: 123968504

Gene position: 837779-839362 (Clockwise)

Preceding gene: 123968502

Following gene: 123968506

Centisome position: 50.17

GC content: 29.67

Gene sequence:

>1584_bases
ATGAATGGAGATTTAAACTCTTGGGATAAATTTTGTAATTATCTTTGGTTTGATAAAAAATTAAATATTTGGTTAGACAT
AAGCAAAATTAATTTCACAAGTAAAGAGATAAAAAATTTAGAAGATAAATTTAAAGATGTTTTTTCATCAATAAAAGAAT
TAGAAAATGGTGCAATCTCAAATATTGATGAAAATAGACAAGTTGGACATTATTGGCTTAGAAATCCATCAATTTCACCC
TCTTCAAAAATAGGAGAAGAAATTAGAGCAGATATTAATTCAATCTCTGAATTTGGAAAACAAATTTTAAATGGGGATAT
TAAGAATAAGAATAATCAGCAGTATACTGATGTTCTATGGATAGGAATTGGTGGAAGTGGATTAGGACCATTACTTATTA
CAGAGTCACTGCAGAAGTGTTCTAAAGGCTTAAATTTTTCTTATATCGATAATGTTGATCCTTTTTTAATTAGCGAAAAG
TTAGAAGAGTTATCTGAAAAATTATCAACAACATTATTTGTAGTAGTAAGCAAATCAGGTGGTACGCCTGAACCTAGAAT
TGCTATGGAAATTATTAAAAGTCACTGCGAAAACAATTCTCTTGAATGGAATTCTAATGCTATAGCTATAACTATGAAAG
GTAGTAAGTTATTCAAAAAAGCTACTTCTGAAAATTGGTTAAAAATATTTAATTTGCAAGATTGGGTTGGTGGAAGAACT
AGTATTACAAGCTCTGTGGGATTACTTCCATTAGCTCTTATTAATGAAAATATATCTGAATTTATCAGAGGTGCATCATT
AATGGATGAAACCACACGTATAAGAGATTTTAAAAATAATCCAGCAGCACTATTATCATCCGCATGGTATTTAACTGGGG
ATGGTATTGGAAAGAGAGATATGGTCGTATTACCTTATAGAGATAGGTTACAGGTTTTTAGTAAATATCTTCAGCAATTA
GTAATGGAATCATTAGGAAAGAAATTTAATAGGAATGGTCAAGTAGTTAATCAAGGTATTTCCGTTTTTGGTAATAAAGG
ATCTACAGATCAGCATGCCTATGTTCAGCAACTGAGAGATGGTATTGATAATTTCTTTTGTATTTTTATTGAATTATTAG
ATTCTCCATCTACTAATATATTTGATGAAAAAGAGAATCCTAAAGAATATCTTTCTGGTTTTTTGCAAGGAACCAGATCA
GCACTCTCTAGTGAAAACAGACAAAGTATCACTATTACGTTAGAAAAGTTAAATTGTTTTTCACTAGGTGCCTTAATCGC
TTTATTTGAAAGGGCTGTATCCTTCTACGCTGAATTGGTAAATATAAATGCATATGATCAACCTGGAGTTGAAGCTGGAA
AGAAAGCAGCTGCAAATATTATTGAGTATCAACAAAAAGTAAGTCATTTATTAGATGAAGGTGGAGAATATTCTATAAAT
GACATAACATCATTATTTGATAATTCAGTTAGTGAACCTATATTTTTTATACTCCGTGAAATGTGTTTCGGTAATGATAA
TTATTTAGTTAAGGGCGATTGGTCAAATCCAAATTCATTAGTTATTCAAAAAATAAATTCTTAA

Upstream 100 bases:

>100_bases
TATTTGAAGATAATAATTTAAACAAATTTAAATGATTCAAATCTATGTACTATTCGTATAGATATAATTGAATAATAAAT
AAAAGAAACAAATATATAAA

Downstream 100 bases:

>100_bases
ACAACAATATTCATTATTTTTCCTTTAACAATAATTATTTTTCTTATTTCCTTATCTTGAGTCCATTTTAATATGTTAGG
TCTTTTAAGAGTCAATTCTT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELSEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSIN
DITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS

Sequences:

>Translated_527_residues
MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELSEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSIN
DITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS
>Mature_527_residues
MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAISNIDENRQVGHYWLRNPSISP
SSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLWIGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEK
LEELSEKLSTTLFVVVSKSGGTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRT
SITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRDMVVLPYRDRLQVFSKYLQQL
VMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRDGIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRS
ALSSENRQSITITLEKLNCFSLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSIN
DITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=491, Percent_Identity=29.938900203666, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI296080693, Length=487, Percent_Identity=27.5154004106776, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1790457, Length=500, Percent_Identity=30.8, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71996703, Length=440, Percent_Identity=30, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71996708, Length=440, Percent_Identity=30, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319673, Length=435, Percent_Identity=29.8850574712644, Blast_Score=156, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24651916, Length=460, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24651914, Length=460, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17737445, Length=460, Percent_Identity=30.4347826086957, Blast_Score=183, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59274; Mature: 59274

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAIS
CCCCCCCHHHHHHHEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NIDENRQVGHYWLRNPSISPSSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLW
CCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEKLEELSEKLSTTLFVVVSKSG
EEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC
GTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRT
CCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHCCCCCEEEECCHHHCCCCH
SITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRD
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCC
MVVLPYRDRLQVFSKYLQQLVMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRD
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHH
GIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRSALSSENRQSITITLEKLNCF
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHH
SLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC
>Mature Secondary Structure
MNGDLNSWDKFCNYLWFDKKLNIWLDISKINFTSKEIKNLEDKFKDVFSSIKELENGAIS
CCCCCCCHHHHHHHEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
NIDENRQVGHYWLRNPSISPSSKIGEEIRADINSISEFGKQILNGDIKNKNNQQYTDVLW
CCCCCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IGIGGSGLGPLLITESLQKCSKGLNFSYIDNVDPFLISEKLEELSEKLSTTLFVVVSKSG
EEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCEEEEEEECCC
GTPEPRIAMEIIKSHCENNSLEWNSNAIAITMKGSKLFKKATSENWLKIFNLQDWVGGRT
CCCCHHHHHHHHHHHCCCCCEEECCCEEEEEECCHHHHHHHCCCCCEEEECCHHHCCCCH
SITSSVGLLPLALINENISEFIRGASLMDETTRIRDFKNNPAALLSSAWYLTGDGIGKRD
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHCCCEEECCCCCCCC
MVVLPYRDRLQVFSKYLQQLVMESLGKKFNRNGQVVNQGISVFGNKGSTDQHAYVQQLRD
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCCCCCHHHHHHHHHHH
GIDNFFCIFIELLDSPSTNIFDEKENPKEYLSGFLQGTRSALSSENRQSITITLEKLNCF
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHH
SLGALIALFERAVSFYAELVNINAYDQPGVEAGKKAAANIIEYQQKVSHLLDEGGEYSIN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
DITSLFDNSVSEPIFFILREMCFGNDNYLVKGDWSNPNSLVIQKINS
HHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA