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The map label for this gene is purN [H]

Identifier: 123968503

GI number: 123968503

Start: 836939

End: 837595

Strand: Reverse

Name: purN [H]

Synonym: A9601_09701

Alternate gene names: 123968503

Gene position: 837595-836939 (Counterclockwise)

Preceding gene: 123968505

Following gene: 123968501

Centisome position: 50.16

GC content: 29.83

Gene sequence:

>657_bases
TTGGATAGATCATTTAATTACATAATTTCGCCTGAGATATCTGAATTTAGAAGATTTTCCCCTAAATTAAAAATAGGTGT
ACTAGCTTCTGGGAAAGGAACAAACTTTCAGGAATTAATTGATCTCTCAGAAAAAGGAGAATTAGATATAGATATAAAAG
TTCTAATAACTAACAAAGATGATGCAGGATGTATAAAGAGAGCTGAAAGTAATAAAATACCTCACAAAATTATAAGAGGC
AAAGACTTTTCGCAAAAAGAACTATTTGAATTAGAAATTATAAATACTTTAATTCATTACGATGTTGAACTTGTAGTTAT
GGCTGGCTGGATGAAAATTGTTTCTCCTTTTTTTATTAATAAATTTAAGAATAAGATAATAAATATTCACCCTTCATTAC
TTCCCGCATATAAAGGTGGTTCTGCGATAAAGGACTCTGTATTAAATGGTTCAAAAATAACTGGTTGTTCAGTACATTTT
GTAGAAGAGGAGGTAGATAGTGGATCATTGATAATGCAAGCTGCATTGTCAATTAGAGATGATGATGATATTGAATCACT
TTCCAAAAGGATACAAATGCTTGAGCATAAAATTTTACCTCACTCAATCTCTCAAGCTGGGTTTTTGATAAGAAGTAATT
TTATGGAAAATTATTAG

Upstream 100 bases:

>100_bases
ATTATTATCTTCAAATAAATATGTTTTTGAATATAAACAATTAAAAATGAGGGTTTTTTTTATTTCATATGAATTTATCA
TTGGATAAAATAAAAAAATT

Downstream 100 bases:

>100_bases
TTAAATCAAGACCTTCATCCATTGAAAATCCACTCATAAGATTTAAATTTTGAATTGCTTGCCCAGTCTGACCTTTTAAC
AAATTATCAATTGCAGATAA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MDRSFNYIISPEISEFRRFSPKLKIGVLASGKGTNFQELIDLSEKGELDIDIKVLITNKDDAGCIKRAESNKIPHKIIRG
KDFSQKELFELEIINTLIHYDVELVVMAGWMKIVSPFFINKFKNKIINIHPSLLPAYKGGSAIKDSVLNGSKITGCSVHF
VEEEVDSGSLIMQAALSIRDDDDIESLSKRIQMLEHKILPHSISQAGFLIRSNFMENY

Sequences:

>Translated_218_residues
MDRSFNYIISPEISEFRRFSPKLKIGVLASGKGTNFQELIDLSEKGELDIDIKVLITNKDDAGCIKRAESNKIPHKIIRG
KDFSQKELFELEIINTLIHYDVELVVMAGWMKIVSPFFINKFKNKIINIHPSLLPAYKGGSAIKDSVLNGSKITGCSVHF
VEEEVDSGSLIMQAALSIRDDDDIESLSKRIQMLEHKILPHSISQAGFLIRSNFMENY
>Mature_218_residues
MDRSFNYIISPEISEFRRFSPKLKIGVLASGKGTNFQELIDLSEKGELDIDIKVLITNKDDAGCIKRAESNKIPHKIIRG
KDFSQKELFELEIINTLIHYDVELVVMAGWMKIVSPFFINKFKNKIINIHPSLLPAYKGGSAIKDSVLNGSKITGCSVHF
VEEEVDSGSLIMQAALSIRDDDDIESLSKRIQMLEHKILPHSISQAGFLIRSNFMENY

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=182, Percent_Identity=37.3626373626374, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI209869995, Length=182, Percent_Identity=37.3626373626374, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI209869993, Length=182, Percent_Identity=37.3626373626374, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1788846, Length=182, Percent_Identity=35.1648351648352, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787483, Length=195, Percent_Identity=27.1794871794872, Blast_Score=87, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17567511, Length=182, Percent_Identity=38.4615384615385, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320616, Length=199, Percent_Identity=28.643216080402, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582400, Length=183, Percent_Identity=38.7978142076503, Blast_Score=147, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 24630; Mature: 24630

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRSFNYIISPEISEFRRFSPKLKIGVLASGKGTNFQELIDLSEKGELDIDIKVLITNKD
CCCCCCEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEEEEEECCC
DAGCIKRAESNKIPHKIIRGKDFSQKELFELEIINTLIHYDVELVVMAGWMKIVSPFFIN
CHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
KFKNKIINIHPSLLPAYKGGSAIKDSVLNGSKITGCSVHFVEEEVDSGSLIMQAALSIRD
HHHHHEEEECCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCC
DDDIESLSKRIQMLEHKILPHSISQAGFLIRSNFMENY
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRSFNYIISPEISEFRRFSPKLKIGVLASGKGTNFQELIDLSEKGELDIDIKVLITNKD
CCCCCCEEECCCHHHHHHCCCCEEEEEEECCCCCCHHHHHCCCCCCCEEEEEEEEEECCC
DAGCIKRAESNKIPHKIIRGKDFSQKELFELEIINTLIHYDVELVVMAGWMKIVSPFFIN
CHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
KFKNKIINIHPSLLPAYKGGSAIKDSVLNGSKITGCSVHFVEEEVDSGSLIMQAALSIRD
HHHHHEEEECCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCC
DDDIESLSKRIQMLEHKILPHSISQAGFLIRSNFMENY
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA