Click here to switch to the map view.

The map label for this gene is ruvA [H]

Identifier: 123968451

GI number: 123968451

Start: 790225

End: 790902

Strand: Reverse

Name: ruvA [H]

Synonym: A9601_09181

Alternate gene names: 123968451

Gene position: 790902-790225 (Counterclockwise)

Preceding gene: 123968452

Following gene: 123968450

Centisome position: 47.36

GC content: 25.22

Gene sequence:

>678_bases
TTGATTAGTTGGATAAATGGAGATTTAGTTGATTTATGGCAAACTAATCAAAAATCTTTTGTTTTAATAAATTGTCAAGG
ATTAGGATACGAAATACAAATACTAGAATCCTTTTTTCTCAAATTAAAAACAAATCAGATATCTACTAAAAACATCACTC
TTTGGATAAAGCATATTAAAAAAGAAGATTCAGATTTATTATTTGGCTTTACATCAAAGGATCAAAAGAATTTCTTTATT
GAAATTTTAAGTATTCGAGGTGTTGGATCTCAAATTGGTATTGGGATATTAAACAAATTTTCTATTAGTGAAGTTATAAA
TGCAATAAAAACACAAGACAAAAAATTAATTTGTTCCGTACCTGGTATAGGACAAAAAATGAGTGAGCGGTTAATTTTAG
AATTAAAAAGTAAATTTAAAAGCGAAATATTATCTGAAGAAGAAAAAAGCAAAGATGAATTTGAGATTAAGGATCCTGAG
ATAATTAAAATGATAGAAGACCTTCAGTTAACCCTTCAATCATTAAGTTACAAAAACAAAGAAATAAATACTATTTTGCC
AATTATTATTAAAGAAATAGATCACCTAGGTAAAAAAGAAAATAGTTTATCATTTGAAAAACTATTGAAATTGGCTATGC
ATTATCTTGATGAAGATAGTAGTAATAAAGATAGATGA

Upstream 100 bases:

>100_bases
AATTGCATTATCCTCATCTAGAGGTAAAGACAGGTTTTGGGCCGTACCAGCGGGCGGTACTGCAGGAGCGCTAATTGGAT
GTCAGGTGGATGGTGGTTAA

Downstream 100 bases:

>100_bases
CGTAGTATCATAGGTAAAAAGAAATAAATTTATGTCATTAGATACAGCTGAAAAACAGAAGCTTATTGAAAATCATCAAG
TGCATCCTACTGATACAGGT

Product: putative holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MISWINGDLVDLWQTNQKSFVLINCQGLGYEIQILESFFLKLKTNQISTKNITLWIKHIKKEDSDLLFGFTSKDQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKDEFEIKDPE
IIKMIEDLQLTLQSLSYKNKEINTILPIIIKEIDHLGKKENSLSFEKLLKLAMHYLDEDSSNKDR

Sequences:

>Translated_225_residues
MISWINGDLVDLWQTNQKSFVLINCQGLGYEIQILESFFLKLKTNQISTKNITLWIKHIKKEDSDLLFGFTSKDQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKDEFEIKDPE
IIKMIEDLQLTLQSLSYKNKEINTILPIIIKEIDHLGKKENSLSFEKLLKLAMHYLDEDSSNKDR
>Mature_225_residues
MISWINGDLVDLWQTNQKSFVLINCQGLGYEIQILESFFLKLKTNQISTKNITLWIKHIKKEDSDLLFGFTSKDQKNFFI
EILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSVPGIGQKMSERLILELKSKFKSEILSEEEKSKDEFEIKDPE
IIKMIEDLQLTLQSLSYKNKEINTILPIIIKEIDHLGKKENSLSFEKLLKLAMHYLDEDSSNKDR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=141, Percent_Identity=30.4964539007092, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 25942; Mature: 25942

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISWINGDLVDLWQTNQKSFVLINCQGLGYEIQILESFFLKLKTNQISTKNITLWIKHIK
CCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHEEEEEECC
KEDSDLLFGFTSKDQKNFFIEILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSV
CCCCCEEEEECCCCCCCEEEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHCCCCEEEEEC
PGIGQKMSERLILELKSKFKSEILSEEEKSKDEFEIKDPEIIKMIEDLQLTLQSLSYKNK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
EINTILPIIIKEIDHLGKKENSLSFEKLLKLAMHYLDEDSSNKDR
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISWINGDLVDLWQTNQKSFVLINCQGLGYEIQILESFFLKLKTNQISTKNITLWIKHIK
CCCCCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHHEEEEEECC
KEDSDLLFGFTSKDQKNFFIEILSIRGVGSQIGIGILNKFSISEVINAIKTQDKKLICSV
CCCCCEEEEECCCCCCCEEEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHCCCCEEEEEC
PGIGQKMSERLILELKSKFKSEILSEEEKSKDEFEIKDPEIIKMIEDLQLTLQSLSYKNK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
EINTILPIIIKEIDHLGKKENSLSFEKLLKLAMHYLDEDSSNKDR
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA