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The map label for this gene is pgl [H]

Identifier: 123968366

GI number: 123968366

Start: 723259

End: 723996

Strand: Direct

Name: pgl [H]

Synonym: A9601_08331

Alternate gene names: 123968366

Gene position: 723259-723996 (Clockwise)

Preceding gene: 123968365

Following gene: 123968367

Centisome position: 43.31

GC content: 28.59

Gene sequence:

>738_bases
ATGGATGAAATGATTGAAAAGGTCAAAAATGGATACACCTTAAATATATGCAAAGACAAGTTAGAACTATCAACAGCGGT
TTTTAAGTTTATTCAAAGCCATATTATTCATACTTTAAAAAAGAAAGACAGATTCAAATTTTGTGTAAGTGGAGGTTCAA
CTCCTAAATCTGTTTATCATCTCTTATCTCATAATGATCTTCAATGGGATATGGTTGATGTCTTTTTAGGAGATGAAAGA
TGTGTTGATCCAAATTCAGAATTAAGTAACTCGTTAATGTTGAGAAATTCTTTGCTAACTAATTTTGGATCTAAAGCTTA
TTTTTATGAAATTTTCAATGATTTAAACGCTGATGATGAAACTACTAAAAATCAATTTATTTCTAAATTATTTGAAAAAT
GCGGATCAAACCCTCCAACTTTTGATTTAACATTATTAGGCCTTGGAGATGATGGCCATACAGCCTCACTATTCCCTTAT
CAAAAAAATAATAATGTAGATGATTTTGTTATTTTTAATGAAGGTAAAGGTTTAAAAAGAATTTCATTAACTCCAAAGGT
TCTTTCAGCTTCTTCAAAGATAGTATTTTTAGTTAGTGGAGCTTCTAAAAGAATTGCTCTTGAGAGGTTATTAGATGAAA
AAGAGCCACCAGATAGAACACCATCAAAATTAATAAAATCTAATAATCAAATTTCAATATTTTGTGATCAGGAATCAGCA
AAAGAATTAGAAATTTAG

Upstream 100 bases:

>100_bases
GAACTAATAGACTTCCTCAGAATCTTGTTCAGGCAATGAGAGACTGTTTTGGCTCCCATACATATGAAAGAATTGATAGG
GAAGGTAGTTTTCATACTGA

Downstream 100 bases:

>100_bases
TTAAAGTCTATTAATAATTTAAATTATTTAATGAGTAAGAAAAAATTTTTATTCCAGAAAAAGGAGTTCGATGGTTGGAA
AACATTAAATGATACTGTTA

Product: putative 6-phosphogluconolactonase (DevB, Pgl)

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MDEMIEKVKNGYTLNICKDKLELSTAVFKFIQSHIIHTLKKKDRFKFCVSGGSTPKSVYHLLSHNDLQWDMVDVFLGDER
CVDPNSELSNSLMLRNSLLTNFGSKAYFYEIFNDLNADDETTKNQFISKLFEKCGSNPPTFDLTLLGLGDDGHTASLFPY
QKNNNVDDFVIFNEGKGLKRISLTPKVLSASSKIVFLVSGASKRIALERLLDEKEPPDRTPSKLIKSNNQISIFCDQESA
KELEI

Sequences:

>Translated_245_residues
MDEMIEKVKNGYTLNICKDKLELSTAVFKFIQSHIIHTLKKKDRFKFCVSGGSTPKSVYHLLSHNDLQWDMVDVFLGDER
CVDPNSELSNSLMLRNSLLTNFGSKAYFYEIFNDLNADDETTKNQFISKLFEKCGSNPPTFDLTLLGLGDDGHTASLFPY
QKNNNVDDFVIFNEGKGLKRISLTPKVLSASSKIVFLVSGASKRIALERLLDEKEPPDRTPSKLIKSNNQISIFCDQESA
KELEI
>Mature_245_residues
MDEMIEKVKNGYTLNICKDKLELSTAVFKFIQSHIIHTLKKKDRFKFCVSGGSTPKSVYHLLSHNDLQWDMVDVFLGDER
CVDPNSELSNSLMLRNSLLTNFGSKAYFYEIFNDLNADDETTKNQFISKLFEKCGSNPPTFDLTLLGLGDDGHTASLFPY
QKNNNVDDFVIFNEGKGLKRISLTPKVLSASSKIVFLVSGASKRIALERLLDEKEPPDRTPSKLIKSNNQISIFCDQESA
KELEI

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=195, Percent_Identity=28.7179487179487, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533060, Length=242, Percent_Identity=25.2066115702479, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533058, Length=242, Percent_Identity=25.2066115702479, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324362, Length=215, Percent_Identity=29.7674418604651, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319918, Length=212, Percent_Identity=29.2452830188679, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321957, Length=243, Percent_Identity=27.1604938271605, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321687, Length=219, Percent_Identity=29.2237442922374, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 27702; Mature: 27702

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEMIEKVKNGYTLNICKDKLELSTAVFKFIQSHIIHTLKKKDRFKFCVSGGSTPKSVYH
CCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
LLSHNDLQWDMVDVFLGDERCVDPNSELSNSLMLRNSLLTNFGSKAYFYEIFNDLNADDE
HHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
TTKNQFISKLFEKCGSNPPTFDLTLLGLGDDGHTASLFPYQKNNNVDDFVIFNEGKGLKR
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEECCCCCEE
ISLTPKVLSASSKIVFLVSGASKRIALERLLDEKEPPDRTPSKLIKSNNQISIFCDQESA
EECCHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCC
KELEI
CCCCC
>Mature Secondary Structure
MDEMIEKVKNGYTLNICKDKLELSTAVFKFIQSHIIHTLKKKDRFKFCVSGGSTPKSVYH
CCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
LLSHNDLQWDMVDVFLGDERCVDPNSELSNSLMLRNSLLTNFGSKAYFYEIFNDLNADDE
HHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
TTKNQFISKLFEKCGSNPPTFDLTLLGLGDDGHTASLFPYQKNNNVDDFVIFNEGKGLKR
HHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCEEEEEECCCCCEE
ISLTPKVLSASSKIVFLVSGASKRIALERLLDEKEPPDRTPSKLIKSNNQISIFCDQESA
EECCHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCCC
KELEI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]