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The map label for this gene is recG [H]

Identifier: 123968352

GI number: 123968352

Start: 703476

End: 705923

Strand: Direct

Name: recG [H]

Synonym: A9601_08171

Alternate gene names: 123968352

Gene position: 703476-705923 (Clockwise)

Preceding gene: 123968351

Following gene: 123968354

Centisome position: 42.13

GC content: 28.19

Gene sequence:

>2448_bases
GTGACTATTAGCGGGAATAATAATAAATTAATTAAAGATTGGATAAGACCTCTTCAAAAATCTCTTACTATTGAAACTGA
AAATAAATTTATTAACACTTTAGGAAGAGAAAAATATTTTAATGATTATTTGCATGAATCACTAAAAAAACTAGATAATC
TAAATCTCTCAGGCGAATATTTAAGGATATTTGATGAATTTTCTAAAAAATATAATGAATATAATAAATTAGATGAAAAT
CAAAGAAAAAGGTTAGTTATAGATACAAGAAAAAATCTTTATAAACTAGGTAAAACCTTAGAAATAGAAAGTTCTAATAA
TAATGTTTTTCTGGATAAAGCTGATGCAAGTTTGTCTATTGATTCAGATATTTCATTAATAAAAAATGTAGGAAAAGTTT
ATAAAAATAAGCTTAATGAATTAGGGATATTTCATATAAAAGATCTAATTAATTATTTCCCAAGAACATATCTAGACTAT
ACGAATAGAGTAAAGATAATAAATTTAAAACCAGATAATTTATACACGTGCATTGCAAACGTTAAAAGGTTTTATATTCA
TAAGAGTAAAAAAAATAGTAATTTATCAATAATGAATATTGTTGTTTTTGATGAAACGTCTTCAATAAAGGTTACAAAAT
TTTTTTTAGGAAAAAGATTTAGATCTTACTCCTTCTTCACATCTCAAAAATCTTTGTATACTCCTGGAACTAAATTAGCA
ATTTCCGGTAAGGTTAAATTGACAGAGTATGGCAAAACTTTTGTAGATCCGCAGATTGAAATTCTTAAGGACAACAATGA
TAATTTTAATTTCTCAGGCAAAATATTACCCTTGTATTCATTAGGTGAAGCATTATCGAATATGAGTTTTATAAAACTTA
TGAAAAAGGTACTAATTTATGCAAAGCAATATCCAGAAATTTTAAATAAAAAGCAACTTGATTCATTATCTTTATTATCA
AAAGGAGAGTCGTTGATTAATATTCATTTTCCACCAACTCAACAGGCACTTATTGAGTCAAAAAAACGTTTGGTTTTTGA
TGAGTTATTCCTACTTCAAATAAAGTTCCTACTTAGAAAAAGAAAGACGAAAAAAAATGTAAATCCCCAACAATTACCTC
AAAAGAAATCTTTATTAAAAGAATTTTTAGATACTTTTCCTTTTGAATTAACAAAATCTCAAGAAAACGTTTTAAATGAA
ATTAAGAAAGATTTATCTAATCCCGTACCAATGTCTAGATTGCTTCAGGGAGATGTGGGAAGCGGTAAAACTATAATTGC
AATAGCGTCTCTTTTGCTTGTAATTGAAAAAAACCTGCAAGGTGCAATTATGGTCCCAACTGAGGTATTGGCAGAACAGC
ATTATAAAAATTTATTAAAATATTTGAACCCCCTTTTTGTTTCTGTTGAATTACTTACTGGGAATACTCCTCAAAAAAAG
AGAAAAGAAATTTTCTCTAATTTGAACAATGGATTAGTTGATATCCTCGTAGGTACTCATGCATTATTTGAGGATAAAGT
CATCTTTAATGCATTAGGCATGGTGGTAATTGATGAACAACATAGATTTGGAGTTACTCAAAGAAATAGATTACTAAATA
AAGGAGAAAATACTAACTTGTTATCAATGACAGCAACACCAATTCCAAGAACTCTTGCGCTTTCTATTTATGGTGATTTA
GATGTGAGTCAAATTACAGAACTACCTCCTGGGAGAGTTCCAATAACAACAAAAATAATTTCAGAAGACGATTTAACTAA
CTTGTTCAAGATTGTTGAAGATGAGATCAATAAGGGAAAGCAAGCTTATGTTATTTTGCCACTTATAGAAGATTCAGAAA
AAATGAATTTAAGCTCCGCAAAGAAAACATTCAAACATTTATCAGAAGAGGTCTTTTTTAATAAAAAAGTTGGATTATTA
CATGGCAAATTAAGTTCACAAGAAAAAAATGAAGTAATTAATTCTTTTTTAAAGAATGAAATTAATATATTGGTTTCAAC
CACAGTAATTGAGGTTGGTATTGATGTCCCTAACGCCACAATTATGATTATTTATAATTCGGATAGATTTGGATTGTCCC
AGCTACATCAATTAAGGGGGAGAGTTGGTAGAGGATCAACCAAATCTTTTTGTTATCTGGTAACCCCCGATAAAAATGGA
TTAGAAAATAAACGACTTTGTGTTTTGCAAAAATCTAATGATGGCTTTTATATTGCTGAAAAAGACTTGGAGCTTAGAGG
TCCAGGTCAGATTTTAGGATATAGACAATCTGGATTGCCTGATTTTGTACTGGACAATTTACCTAATAATAAATTTCTTA
TTGATAAGGCCCGTGAAGAGGCTATTAAGATTGTTAGTGATGATCCTGATTTAAAAGAAAATATTGTTTTAAGGAAAATA
CTTATTGATAATTCTGATAATAAATTCATTCATGATTTCTTAAATTGA

Upstream 100 bases:

>100_bases
AAAAATCAATTTCAGCGTTTGATTAAAAAAGAGACATATTGGAGGCAAAAAGAAATAACCTTGAATAAGATACGTTGAAA
AAATAACTCTTTTTTCAAAT

Downstream 100 bases:

>100_bases
AAACTATCATTGTAATTTTTGATATTTATGCCACTATAAATCAATTGCAAATTTCAATTGAAAGTTTGGAATAAAATACC
AATTAAAGATAATGGAGATA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTISGNNNKLIKDWIRPLQKSLTIETENKFINTLGREKYFNDYLHESLKKLDNLNLSGEYLRIFDEFSKKYNEYNKLDEN
QRKRLVIDTRKNLYKLGKTLEIESSNNNVFLDKADASLSIDSDISLIKNVGKVYKNKLNELGIFHIKDLINYFPRTYLDY
TNRVKIINLKPDNLYTCIANVKRFYIHKSKKNSNLSIMNIVVFDETSSIKVTKFFLGKRFRSYSFFTSQKSLYTPGTKLA
ISGKVKLTEYGKTFVDPQIEILKDNNDNFNFSGKILPLYSLGEALSNMSFIKLMKKVLIYAKQYPEILNKKQLDSLSLLS
KGESLINIHFPPTQQALIESKKRLVFDELFLLQIKFLLRKRKTKKNVNPQQLPQKKSLLKEFLDTFPFELTKSQENVLNE
IKKDLSNPVPMSRLLQGDVGSGKTIIAIASLLLVIEKNLQGAIMVPTEVLAEQHYKNLLKYLNPLFVSVELLTGNTPQKK
RKEIFSNLNNGLVDILVGTHALFEDKVIFNALGMVVIDEQHRFGVTQRNRLLNKGENTNLLSMTATPIPRTLALSIYGDL
DVSQITELPPGRVPITTKIISEDDLTNLFKIVEDEINKGKQAYVILPLIEDSEKMNLSSAKKTFKHLSEEVFFNKKVGLL
HGKLSSQEKNEVINSFLKNEINILVSTTVIEVGIDVPNATIMIIYNSDRFGLSQLHQLRGRVGRGSTKSFCYLVTPDKNG
LENKRLCVLQKSNDGFYIAEKDLELRGPGQILGYRQSGLPDFVLDNLPNNKFLIDKAREEAIKIVSDDPDLKENIVLRKI
LIDNSDNKFIHDFLN

Sequences:

>Translated_815_residues
MTISGNNNKLIKDWIRPLQKSLTIETENKFINTLGREKYFNDYLHESLKKLDNLNLSGEYLRIFDEFSKKYNEYNKLDEN
QRKRLVIDTRKNLYKLGKTLEIESSNNNVFLDKADASLSIDSDISLIKNVGKVYKNKLNELGIFHIKDLINYFPRTYLDY
TNRVKIINLKPDNLYTCIANVKRFYIHKSKKNSNLSIMNIVVFDETSSIKVTKFFLGKRFRSYSFFTSQKSLYTPGTKLA
ISGKVKLTEYGKTFVDPQIEILKDNNDNFNFSGKILPLYSLGEALSNMSFIKLMKKVLIYAKQYPEILNKKQLDSLSLLS
KGESLINIHFPPTQQALIESKKRLVFDELFLLQIKFLLRKRKTKKNVNPQQLPQKKSLLKEFLDTFPFELTKSQENVLNE
IKKDLSNPVPMSRLLQGDVGSGKTIIAIASLLLVIEKNLQGAIMVPTEVLAEQHYKNLLKYLNPLFVSVELLTGNTPQKK
RKEIFSNLNNGLVDILVGTHALFEDKVIFNALGMVVIDEQHRFGVTQRNRLLNKGENTNLLSMTATPIPRTLALSIYGDL
DVSQITELPPGRVPITTKIISEDDLTNLFKIVEDEINKGKQAYVILPLIEDSEKMNLSSAKKTFKHLSEEVFFNKKVGLL
HGKLSSQEKNEVINSFLKNEINILVSTTVIEVGIDVPNATIMIIYNSDRFGLSQLHQLRGRVGRGSTKSFCYLVTPDKNG
LENKRLCVLQKSNDGFYIAEKDLELRGPGQILGYRQSGLPDFVLDNLPNNKFLIDKAREEAIKIVSDDPDLKENIVLRKI
LIDNSDNKFIHDFLN
>Mature_814_residues
TISGNNNKLIKDWIRPLQKSLTIETENKFINTLGREKYFNDYLHESLKKLDNLNLSGEYLRIFDEFSKKYNEYNKLDENQ
RKRLVIDTRKNLYKLGKTLEIESSNNNVFLDKADASLSIDSDISLIKNVGKVYKNKLNELGIFHIKDLINYFPRTYLDYT
NRVKIINLKPDNLYTCIANVKRFYIHKSKKNSNLSIMNIVVFDETSSIKVTKFFLGKRFRSYSFFTSQKSLYTPGTKLAI
SGKVKLTEYGKTFVDPQIEILKDNNDNFNFSGKILPLYSLGEALSNMSFIKLMKKVLIYAKQYPEILNKKQLDSLSLLSK
GESLINIHFPPTQQALIESKKRLVFDELFLLQIKFLLRKRKTKKNVNPQQLPQKKSLLKEFLDTFPFELTKSQENVLNEI
KKDLSNPVPMSRLLQGDVGSGKTIIAIASLLLVIEKNLQGAIMVPTEVLAEQHYKNLLKYLNPLFVSVELLTGNTPQKKR
KEIFSNLNNGLVDILVGTHALFEDKVIFNALGMVVIDEQHRFGVTQRNRLLNKGENTNLLSMTATPIPRTLALSIYGDLD
VSQITELPPGRVPITTKIISEDDLTNLFKIVEDEINKGKQAYVILPLIEDSEKMNLSSAKKTFKHLSEEVFFNKKVGLLH
GKLSSQEKNEVINSFLKNEINILVSTTVIEVGIDVPNATIMIIYNSDRFGLSQLHQLRGRVGRGSTKSFCYLVTPDKNGL
ENKRLCVLQKSNDGFYIAEKDLELRGPGQILGYRQSGLPDFVLDNLPNNKFLIDKAREEAIKIVSDDPDLKENIVLRKIL
IDNSDNKFIHDFLN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=700, Percent_Identity=36.4285714285714, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1787357, Length=383, Percent_Identity=37.597911227154, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 93263; Mature: 93132

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00185 IPNS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISGNNNKLIKDWIRPLQKSLTIETENKFINTLGREKYFNDYLHESLKKLDNLNLSGEY
CEECCCCCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRIFDEFSKKYNEYNKLDENQRKRLVIDTRKNLYKLGKTLEIESSNNNVFLDKADASLSI
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHCCCEEEEECCCCEEEEEECCCCEEC
DSDISLIKNVGKVYKNKLNELGIFHIKDLINYFPRTYLDYTNRVKIINLKPDNLYTCIAN
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHHHH
VKRFYIHKSKKNSNLSIMNIVVFDETSSIKVTKFFLGKRFRSYSFFTSQKSLYTPGTKLA
HHHHEEEECCCCCCEEEEEEEEEECCCCEEEHHHHHHHHHHCCEEEECCCCEECCCCEEE
ISGKVKLTEYGKTFVDPQIEILKDNNDNFNFSGKILPLYSLGEALSNMSFIKLMKKVLIY
EECEEEEEECCCCCCCCCEEEEECCCCCEEECCEEEEHHHHHHHHCCCHHHHHHHHHHHH
AKQYPEILNKKQLDSLSLLSKGESLINIHFPPTQQALIESKKRLVFDELFLLQIKFLLRK
HHHHHHHHCHHCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKTKKNVNPQQLPQKKSLLKEFLDTFPFELTKSQENVLNEIKKDLSNPVPMSRLLQGDVG
HHHHCCCCHHHCCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCC
SGKTIIAIASLLLVIEKNLQGAIMVPTEVLAEQHYKNLLKYLNPLFVSVELLTGNTPQKK
CCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
RKEIFSNLNNGLVDILVGTHALFEDKVIFNALGMVVIDEQHRFGVTQRNRLLNKGENTNL
HHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHCCEEEECCCHHCCCHHHHHHHCCCCCCCE
LSMTATPIPRTLALSIYGDLDVSQITELPPGRVPITTKIISEDDLTNLFKIVEDEINKGK
EEEECCCCCCEEEEEEECCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
QAYVILPLIEDSEKMNLSSAKKTFKHLSEEVFFNKKVGLLHGKLSSQEKNEVINSFLKNE
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCC
INILVSTTVIEVGIDVPNATIMIIYNSDRFGLSQLHQLRGRVGRGSTKSFCYLVTPDKNG
CEEEEEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCC
LENKRLCVLQKSNDGFYIAEKDLELRGPGQILGYRQSGLPDFVLDNLPNNKFLIDKAREE
CCCCEEEEEEECCCCEEEEECCCCCCCCCCEECCCCCCCCHHHHHCCCCCCEEEEHHHHH
AIKIVSDDPDLKENIVLRKILIDNSDNKFIHDFLN
HEEEECCCCCHHHHHEEEEEEEECCCCCHHHHHCC
>Mature Secondary Structure 
TISGNNNKLIKDWIRPLQKSLTIETENKFINTLGREKYFNDYLHESLKKLDNLNLSGEY
EECCCCCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRIFDEFSKKYNEYNKLDENQRKRLVIDTRKNLYKLGKTLEIESSNNNVFLDKADASLSI
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHCCCEEEEECCCCEEEEEECCCCEEC
DSDISLIKNVGKVYKNKLNELGIFHIKDLINYFPRTYLDYTNRVKIINLKPDNLYTCIAN
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCHHHHHHH
VKRFYIHKSKKNSNLSIMNIVVFDETSSIKVTKFFLGKRFRSYSFFTSQKSLYTPGTKLA
HHHHEEEECCCCCCEEEEEEEEEECCCCEEEHHHHHHHHHHCCEEEECCCCEECCCCEEE
ISGKVKLTEYGKTFVDPQIEILKDNNDNFNFSGKILPLYSLGEALSNMSFIKLMKKVLIY
EECEEEEEECCCCCCCCCEEEEECCCCCEEECCEEEEHHHHHHHHCCCHHHHHHHHHHHH
AKQYPEILNKKQLDSLSLLSKGESLINIHFPPTQQALIESKKRLVFDELFLLQIKFLLRK
HHHHHHHHCHHCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKTKKNVNPQQLPQKKSLLKEFLDTFPFELTKSQENVLNEIKKDLSNPVPMSRLLQGDVG
HHHHCCCCHHHCCHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHCCCCCHHHHHCCCCC
SGKTIIAIASLLLVIEKNLQGAIMVPTEVLAEQHYKNLLKYLNPLFVSVELLTGNTPQKK
CCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
RKEIFSNLNNGLVDILVGTHALFEDKVIFNALGMVVIDEQHRFGVTQRNRLLNKGENTNL
HHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHCCEEEECCCHHCCCHHHHHHHCCCCCCCE
LSMTATPIPRTLALSIYGDLDVSQITELPPGRVPITTKIISEDDLTNLFKIVEDEINKGK
EEEECCCCCCEEEEEEECCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCC
QAYVILPLIEDSEKMNLSSAKKTFKHLSEEVFFNKKVGLLHGKLSSQEKNEVINSFLKNE
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCC
INILVSTTVIEVGIDVPNATIMIIYNSDRFGLSQLHQLRGRVGRGSTKSFCYLVTPDKNG
CEEEEEEEEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCCC
LENKRLCVLQKSNDGFYIAEKDLELRGPGQILGYRQSGLPDFVLDNLPNNKFLIDKAREE
CCCCEEEEEEECCCCEEEEECCCCCCCCCCEECCCCCCCCHHHHHCCCCCCEEEEHHHHH
AIKIVSDDPDLKENIVLRKILIDNSDNKFIHDFLN
HEEEECCCCCHHHHHEEEEEEEECCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]