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The map label for this gene is lig [H]

Identifier: 123968319

GI number: 123968319

Start: 682181

End: 683167

Strand: Reverse

Name: lig [H]

Synonym: A9601_07841

Alternate gene names: 123968319

Gene position: 683167-682181 (Counterclockwise)

Preceding gene: 123968320

Following gene: 123968318

Centisome position: 40.91

GC content: 29.08

Gene sequence:

>987_bases
TTGAGAACTAAACAAGAATATTTAATTAGATATAAAGATGGAAATCTTTATTGTGAACTTGCTGATATTTGGATTGATCC
AAGCAAGCCAGTAAAAAAGGCATTAATAACTCATGCTCATTTTGATCACTTTACATTTGGCTGTGAAGAATACATTTCTA
CTAAGGAAACTGCCATTCTTCTTAAAGAAAGAGTTGGAGATAATATCAAAATCAAGACTTTTGAATATGCAGAAGAATTT
AAGATAAATGGCATTAATATTTCTTTTCATCCATCCGGTCACATCCTTGGATCTAGTCAAATAAGGTTTATTTTTGCTGA
AGAAAAATGGCTAATTTCAGGTGACTTTAAACTTCAAAAAGATCAGACTTGCAAACAATATGAAATAGTAAAAACTGATT
ATTTAATAAGCGAATGTACCTTTGGTTTGCCAATATTTAAGTGGGATGAATCAAATAAAATAGCAAATGATATTTCAAAA
TGGATAACTAATACACCAGAAAAAACTTCTTTACTTTTCTGCTATTCACTTGGAAAAGCTCAGAGATTGTTAAACGAAAT
TAGTCAAACAAATTTTAAAGGCAATATTTATTCCCATGCCAGTATTCACAAAATGAACAAAAGTTATAGGGAACTTGGAA
TTGATATTAAAGATACTATAAAAATTGAAAATAAAAAAAAAATTGATGAACTTAAAGGAAGTCTTATATTATTACCGCCA
TCTTTAAGTAAGGGTTCTTATTTGAAAAATTTAAAAAATATTCAAACAGCTTTCGCGAGTGGATGGATGTCAATAAGAGC
TCTAAGAAAAAGATCAGGATATGATAAAGGATTCGCAATCTCTGATCATGCTGATTGGGATGGAATTCTGGAAGTAGTAA
AAAAGTCTGAAGCAAAAAATGTATTTTTTCATCATGGAGATAGTGAAGCCTTAAGTAAATATTTGGTTGAAAAGGAATCA
ATAAATGTACTTTTATTCGGTAAATAA

Upstream 100 bases:

>100_bases
AATTTGTAGTTATTGCTTTACTAACAATTTCAGCCATAGCTTTATCAAAACAAGCATGGTCATAATTAGCTAAATTAACT
TCATTGTAAGAGATGTAGTT

Downstream 100 bases:

>100_bases
ATATGAGCTTAAAAAAGTTTTCAGAATTATTTGGCGATCTAGATTCAATTAATAGTACAAATAATAAAATTGAAGTTTTA
AAGAATTATTTTTTATCTAA

Product: RNA processing exonuclease

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MRTKQEYLIRYKDGNLYCELADIWIDPSKPVKKALITHAHFDHFTFGCEEYISTKETAILLKERVGDNIKIKTFEYAEEF
KINGINISFHPSGHILGSSQIRFIFAEEKWLISGDFKLQKDQTCKQYEIVKTDYLISECTFGLPIFKWDESNKIANDISK
WITNTPEKTSLLFCYSLGKAQRLLNEISQTNFKGNIYSHASIHKMNKSYRELGIDIKDTIKIENKKKIDELKGSLILLPP
SLSKGSYLKNLKNIQTAFASGWMSIRALRKRSGYDKGFAISDHADWDGILEVVKKSEAKNVFFHHGDSEALSKYLVEKES
INVLLFGK

Sequences:

>Translated_328_residues
MRTKQEYLIRYKDGNLYCELADIWIDPSKPVKKALITHAHFDHFTFGCEEYISTKETAILLKERVGDNIKIKTFEYAEEF
KINGINISFHPSGHILGSSQIRFIFAEEKWLISGDFKLQKDQTCKQYEIVKTDYLISECTFGLPIFKWDESNKIANDISK
WITNTPEKTSLLFCYSLGKAQRLLNEISQTNFKGNIYSHASIHKMNKSYRELGIDIKDTIKIENKKKIDELKGSLILLPP
SLSKGSYLKNLKNIQTAFASGWMSIRALRKRSGYDKGFAISDHADWDGILEVVKKSEAKNVFFHHGDSEALSKYLVEKES
INVLLFGK
>Mature_328_residues
MRTKQEYLIRYKDGNLYCELADIWIDPSKPVKKALITHAHFDHFTFGCEEYISTKETAILLKERVGDNIKIKTFEYAEEF
KINGINISFHPSGHILGSSQIRFIFAEEKWLISGDFKLQKDQTCKQYEIVKTDYLISECTFGLPIFKWDESNKIANDISK
WITNTPEKTSLLFCYSLGKAQRLLNEISQTNFKGNIYSHASIHKMNKSYRELGIDIKDTIKIENKKKIDELKGSLILLPP
SLSKGSYLKNLKNIQTAFASGWMSIRALRKRSGYDKGFAISDHADWDGILEVVKKSEAKNVFFHHGDSEALSKYLVEKES
INVLLFGK

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37745; Mature: 37745

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTKQEYLIRYKDGNLYCELADIWIDPSKPVKKALITHAHFDHFTFGCEEYISTKETAIL
CCCCCEEEEEEECCCEEEEEEEEEECCCHHHHHHHHHHHCCCHHHCCHHHHHCCHHHHHH
LKERVGDNIKIKTFEYAEEFKINGINISFHPSGHILGSSQIRFIFAEEKWLISGDFKLQK
HHHHCCCCEEEEEEECHHHEEEEEEEEEECCCCCEECCCCEEEEEECCEEEEECCEEECC
DQTCKQYEIVKTDYLISECTFGLPIFKWDESNKIANDISKWITNTPEKTSLLFCYSLGKA
CCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHH
QRLLNEISQTNFKGNIYSHASIHKMNKSYRELGIDIKDTIKIENKKKIDELKGSLILLPP
HHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHCCCEEEECC
SLSKGSYLKNLKNIQTAFASGWMSIRALRKRSGYDKGFAISDHADWDGILEVVKKSEAKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCE
VFFHHGDSEALSKYLVEKESINVLLFGK
EEEECCCHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MRTKQEYLIRYKDGNLYCELADIWIDPSKPVKKALITHAHFDHFTFGCEEYISTKETAIL
CCCCCEEEEEEECCCEEEEEEEEEECCCHHHHHHHHHHHCCCHHHCCHHHHHCCHHHHHH
LKERVGDNIKIKTFEYAEEFKINGINISFHPSGHILGSSQIRFIFAEEKWLISGDFKLQK
HHHHCCCCEEEEEEECHHHEEEEEEEEEECCCCCEECCCCEEEEEECCEEEEECCEEECC
DQTCKQYEIVKTDYLISECTFGLPIFKWDESNKIANDISKWITNTPEKTSLLFCYSLGKA
CCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHH
QRLLNEISQTNFKGNIYSHASIHKMNKSYRELGIDIKDTIKIENKKKIDELKGSLILLPP
HHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHCCCHHHEEEECCCHHHHHHCCCEEEECC
SLSKGSYLKNLKNIQTAFASGWMSIRALRKRSGYDKGFAISDHADWDGILEVVKKSEAKN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCE
VFFHHGDSEALSKYLVEKESINVLLFGK
EEEECCCHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA