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The map label for this gene is uvrD [H]

Identifier: 123967864

GI number: 123967864

Start: 300929

End: 303337

Strand: Reverse

Name: uvrD [H]

Synonym: A9601_03271

Alternate gene names: 123967864

Gene position: 303337-300929 (Counterclockwise)

Preceding gene: 123967865

Following gene: 123967863

Centisome position: 18.17

GC content: 32.84

Gene sequence:

>2409_bases
GTGCCTCAAAACAACAATTTCCTTTTTAAGTCCCTAAACAATCAACAACTTCAAGCAGTAAAACATGTTTATGGACCACT
ATTAGTTGTAGCAGGTGCAGGTAGCGGAAAAACTAAGGCACTTACTCACAGAATTGCAAACCTTATTGAAGGTAACTCTA
TAGATCCCTATAACATTCTCGCAGTAACTTTCACTAACAAAGCTGCTAAAGAAATGAAAGCTAGATTAGAGGTTCTTCTG
GCCCAAGAACTAGCTTTTAATCAATTTGGCCAGCCTTGGACAACTCTCAAAGAAATTGATCAAAATCAATTAAGAACAAA
CGTTCACAAAGACAGGCTTCAGAACCTTTGGATCGGTACCTTCCATTCTTTATTTTCAAGACTTCTGAGATACGATATTG
AAAAATATACTGATCCAGAAGGCCTAAAATGGACAAGGCAATTTTCAATTTACGATGAAACAGATTCTCAAACATTAGTA
AAAGAAATTATCAGTCAAGATATGAATCTTGATCCAAAAAGATATGATCCCAAAAAGATTAAAAGATTAATAAGTAATGC
TAAAAATCAATGCTTAACTTCTAATGATCTTTTAGAAAAAGCAGATAATAATTTTGATAAAACAGTTGCAGAAGCCTACA
AGAGATATAGAATATCGCTCTCAAAAAATAATTCTTTAGATTTTGATGATCTTTTACTTTTGCCTGTTTTCTTATTGAGG
CAAAATGATATAGTCAGAGATTACTGGCACAAAAGATTTAAACATATTTTAGTTGACGAATATCAAGACACAAATAGAAC
ACAATATGAACTTATAAAATTAATTACGGCTGGAAATACTGAACCAAAAAAATTCTTCAATTGGGAAGATCGGTCAATTT
TTGTAGTTGGAGATGCTGATCAAAGTATTTATAGTTTCAGAGCAGCTGACTTCAGAATTTTAATTGGTTTTCAAGAAGAT
TTTAAGACTTCTATCAATGACGATACAAAATCATCTTTAATTAAATTGGAAGAAAATTATAGGTCATCTTCCAATATACT
TGATGCTGCAAACTCACTAATTGAAAACAACTCTGAAAGAATTGACAAAGTTTTAAAGGCTACTAAAGAAAAGGGGGAAC
TTTTAACGTTACTCAGCTGTGATGATGAAATTTCCGAGGCAGAAGCAATTACCAATAAAATAAAATCACTCAATAACTAT
AATCAAAACCCAATTTGGAAAAATTTTGCAATTTTATATCGAACCAGAGCTCAGTCGAGAGTATTAGAAGAATCTCTTGT
AAGGTGGCGCATTCCTTATACAATTTTTGGAGGATTACGTTTTTATGATCGAAGAGAAATTAAAGATGCAATAGCATATT
TGAAAGTTCTGGTTAATTCTTCAGATAACGTTAGTCTTTTACGAATCATTAATGTTCCTAGAAGAGGGATTGGTAAGACT
ACTATTCAAAAACTTAATGAACTATCTAATAGGTTAAATATCCCATTATGGGAGGTTCTTAATGATAAGCAAAGTCTTGA
AGAAACAATAGGCCGATCATCAAAAGGAATTAATAAATTTACTGCAGTTATGAATGATCTACTGTGTTACCTTGAAAATT
CTGGTCCAGCTCAACTACTACAACTTATATTAGAAAAAAGTGGTTATTTAAGTGACTTGCTCTCTAATGGGTCTGAAGAA
TCTGAAGATAGAAGAAATAACTTACAAGAACTAATTAATGCAGCTACTCAATATGAAGAAGAAACAGAAAGTGGAGATGT
AGAGGGATTTCTTTCTACAGCAGCCTTAACAACTGATAATGATACGAAGAAAAATAATCCTAACTCTGTAACTCTCATGA
CTCTGCATAATAGTAAAGGTTTAGAATTTCAAAATGTTTTTATCACTGGGCTAGAACAAGGTCTCTTCCCTAGCCATAGA
TCAATAGATACTCCCTCACTTCTTGAAGAGGAAAGAAGATTATGCTATGTAGGTATTACTAGAGCTAAAGAAAGAGTTTT
CTTAAGTCATGCCAGAGAAAGAAGATTATGGGGTGGAATGCGTGAAGCAACAATACCTTCAATATTTCTTTCGGAGATAC
CCGAAGATTTAATGGATGGCGAATTACCACAAACTGGTGGTGCTTCAATTAGAAGAGATTTGCATCTTGATCGCTTAACA
AGAGTTGATCGGAACAATCCAAATGAATTTGTTAACAAACCAATAAATGCAGTAAGGAAATTATATTCAGGGCCAAGTAA
AGGGAAAAGCTGGATAGTTGGAGATAAGCTAATTCACACAAAATTTGGGAAAGGTGAAATAATACATATTTTTGGGAGTG
GGGAAAAAATATCTTTAGCAGTAAAATTTGGTGATAAAGGAAGTAAAATTCTAGATCCCAGATTAGCTCCAATTCGTTAT
GTAAGTTAA

Upstream 100 bases:

>100_bases
AACAATAATGAACTTATAAATTTAAAAAAAGCTTTAGAAGATCTAGAAACGGATTCTGAATCTCGTAGTAAAGTCTGATT
TTTGAAAAACCCTTCCAAAA

Downstream 100 bases:

>100_bases
AAATCATGAACGATATCTCTGATTACATCCAAGGAGAATTAATCAAAACTCCATTTAATCTATATAACCTTATTACTAAA
TACATAGAATCTAATAACAA

Product: UvrD/REP helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 801

Protein sequence:

>802_residues
MPQNNNFLFKSLNNQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLL
AQELAFNQFGQPWTTLKEIDQNQLRTNVHKDRLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLV
KEIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYKRYRISLSKNNSLDFDDLLLLPVFLLR
QNDIVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQED
FKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNY
NQNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTAVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGSEE
SEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHR
SIDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDLHLDRLT
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHTKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRY
VS

Sequences:

>Translated_802_residues
MPQNNNFLFKSLNNQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLL
AQELAFNQFGQPWTTLKEIDQNQLRTNVHKDRLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLV
KEIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYKRYRISLSKNNSLDFDDLLLLPVFLLR
QNDIVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQED
FKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNY
NQNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTAVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGSEE
SEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHR
SIDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDLHLDRLT
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHTKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRY
VS
>Mature_801_residues
PQNNNFLFKSLNNQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNILAVTFTNKAAKEMKARLEVLLA
QELAFNQFGQPWTTLKEIDQNQLRTNVHKDRLQNLWIGTFHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVK
EIISQDMNLDPKRYDPKKIKRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYKRYRISLSKNNSLDFDDLLLLPVFLLRQ
NDIVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDADQSIYSFRAADFRILIGFQEDF
KTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSERIDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYN
QNPIWKNFAILYRTRAQSRVLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKTT
IQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTAVMNDLLCYLENSGPAQLLQLILEKSGYLSDLLSNGSEES
EDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDNDTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRS
IDTPSLLEEERRLCYVGITRAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDLHLDRLTR
VDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHTKFGKGEIIHIFGSGEKISLAVKFGDKGSKILDPRLAPIRYV
S

Specific function: Essential helicase [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=790, Percent_Identity=34.8101265822785, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI48994965, Length=693, Percent_Identity=36.7965367965368, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1787196, Length=428, Percent_Identity=27.3364485981308, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322369, Length=792, Percent_Identity=28.030303030303, Blast_Score=210, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6324477, Length=734, Percent_Identity=23.5694822888283, Blast_Score=114, Evalue=7e-26,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 91838; Mature: 91707

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQNNNFLFKSLNNQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNIL
CCCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVTFTNKAAKEMKARLEVLLAQELAFNQFGQPWTTLKEIDQNQLRTNVHKDRLQNLWIGT
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVKEIISQDMNLDPKRYDPKKI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHH
KRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYKRYRISLSKNNSLDFDDLLLLPVFLLR
HHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
QNDIVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDAD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCC
QSIYSFRAADFRILIGFQEDFKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSER
CHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHH
IDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYNQNPIWKNFAILYRTRAQSR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
HHHHHHHHEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHH
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTAVMNDLLCYLENSGPAQLL
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QLILEKSGYLSDLLSNGSEESEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDN
HHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCC
DTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRSIDTPSLLEEERRLCYVGIT
CCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEHH
RAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDLHLDRLT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHH
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHTKFGKGEIIHIFGSGEKISLA
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCHHEEEECCCCCEEEEEECCCEEEEE
VKFGDKGSKILDPRLAPIRYVS
EEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PQNNNFLFKSLNNQQLQAVKHVYGPLLVVAGAGSGKTKALTHRIANLIEGNSIDPYNIL
CCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCEEE
AVTFTNKAAKEMKARLEVLLAQELAFNQFGQPWTTLKEIDQNQLRTNVHKDRLQNLWIGT
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHSLFSRLLRYDIEKYTDPEGLKWTRQFSIYDETDSQTLVKEIISQDMNLDPKRYDPKKI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHH
KRLISNAKNQCLTSNDLLEKADNNFDKTVAEAYKRYRISLSKNNSLDFDDLLLLPVFLLR
HHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHH
QNDIVRDYWHKRFKHILVDEYQDTNRTQYELIKLITAGNTEPKKFFNWEDRSIFVVGDAD
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEECCC
QSIYSFRAADFRILIGFQEDFKTSINDDTKSSLIKLEENYRSSSNILDAANSLIENNSER
CHHHHHHCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHH
IDKVLKATKEKGELLTLLSCDDEISEAEAITNKIKSLNNYNQNPIWKNFAILYRTRAQSR
HHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VLEESLVRWRIPYTIFGGLRFYDRREIKDAIAYLKVLVNSSDNVSLLRIINVPRRGIGKT
HHHHHHHHEECCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHH
TIQKLNELSNRLNIPLWEVLNDKQSLEETIGRSSKGINKFTAVMNDLLCYLENSGPAQLL
HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
QLILEKSGYLSDLLSNGSEESEDRRNNLQELINAATQYEEETESGDVEGFLSTAALTTDN
HHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCC
DTKKNNPNSVTLMTLHNSKGLEFQNVFITGLEQGLFPSHRSIDTPSLLEEERRLCYVGIT
CCCCCCCCEEEEEEEECCCCCEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEHH
RAKERVFLSHARERRLWGGMREATIPSIFLSEIPEDLMDGELPQTGGASIRRDLHLDRLT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHH
RVDRNNPNEFVNKPINAVRKLYSGPSKGKSWIVGDKLIHTKFGKGEIIHIFGSGEKISLA
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCHHEEEECCCCCEEEEEECCCEEEEE
VKFGDKGSKILDPRLAPIRYVS
EEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA