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The map label for this gene is nudF [H]

Identifier: 123967846

GI number: 123967846

Start: 285955

End: 286518

Strand: Reverse

Name: nudF [H]

Synonym: A9601_03091

Alternate gene names: 123967846

Gene position: 286518-285955 (Counterclockwise)

Preceding gene: 123967847

Following gene: 123967845

Centisome position: 17.16

GC content: 32.8

Gene sequence:

>564_bases
ATGGGCAACAAAAATCTTCTAAAGAGATCCATTTTTAAAGAAAAAATATCTGAGTTAAAGTCTAAAAAATTTAGTTTCGA
AATAAATAGAATTCAGCTTCCAAATGGACACGAAGGTGAATATGGATACATTAAGCATCCTGGGGCAGCATTAGCCGTAC
CTATTACAAAAGACAATAAAGTTATCATTCTTCGGCAATATAGATTTGCTGTTTCAAGGTATTTATTAGAATTTCCAGCA
GGTACATTAGAAATAGGTGAAACACCTATTAATTCAATTCAAAGAGAAATCCAAGAAGAGACTGGTTTCAGTGCAAACAA
ATGGGATGAACTAGGAACTCTTGTCCCTGCTCCTGGTTATGCAGATGAAGAAATATATTTATTTTTAGCTCGTGATTTAA
ACAAACTCAATTACAAAGTTGAAGGAGATTTAGATGAAGACATAGAAGTATTAATTTTAGATCCCGACGAACTAGATAAT
CTTATTTCTAGTGGGGATGAAATTCTTGACGCAAAAACCGTGACGGCTTGGTTTAGAGCTAAACAATTTTTAGATAAATT
ATGA

Upstream 100 bases:

>100_bases
GTAGAAGCCAAAAAATAACAAAGTTTGATGATCCAAAATGGTCTATTAATTGATTTACAAAACCAAAAAATAACTGTTAG
GCTATTTTCATTTACAATTC

Downstream 100 bases:

>100_bases
ATAAACCTAGAATACTTTTCTGGCATAGAAAGGATTTAAGAATATTTGATAATCAAGCTTTAATCAAAGCATTTTCATTA
TCAAATGCTATTACTTCAAC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MGNKNLLKRSIFKEKISELKSKKFSFEINRIQLPNGHEGEYGYIKHPGAALAVPITKDNKVIILRQYRFAVSRYLLEFPA
GTLEIGETPINSIQREIQEETGFSANKWDELGTLVPAPGYADEEIYLFLARDLNKLNYKVEGDLDEDIEVLILDPDELDN
LISSGDEILDAKTVTAWFRAKQFLDKL

Sequences:

>Translated_187_residues
MGNKNLLKRSIFKEKISELKSKKFSFEINRIQLPNGHEGEYGYIKHPGAALAVPITKDNKVIILRQYRFAVSRYLLEFPA
GTLEIGETPINSIQREIQEETGFSANKWDELGTLVPAPGYADEEIYLFLARDLNKLNYKVEGDLDEDIEVLILDPDELDN
LISSGDEILDAKTVTAWFRAKQFLDKL
>Mature_186_residues
GNKNLLKRSIFKEKISELKSKKFSFEINRIQLPNGHEGEYGYIKHPGAALAVPITKDNKVIILRQYRFAVSRYLLEFPAG
TLEIGETPINSIQREIQEETGFSANKWDELGTLVPAPGYADEEIYLFLARDLNKLNYKVEGDLDEDIEVLILDPDELDNL
ISSGDEILDAKTVTAWFRAKQFLDKL

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789800, Length=167, Percent_Identity=28.1437125748503, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 21321; Mature: 21189

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNKNLLKRSIFKEKISELKSKKFSFEINRIQLPNGHEGEYGYIKHPGAALAVPITKDNK
CCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCEEECCCCEEEEEEECCCC
VIILRQYRFAVSRYLLEFPAGTLEIGETPINSIQREIQEETGFSANKWDELGTLVPAPGY
EEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
ADEEIYLFLARDLNKLNYKVEGDLDEDIEVLILDPDELDNLISSGDEILDAKTVTAWFRA
CCCCEEEEEEHHHHHCCEEECCCCCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHH
KQFLDKL
HHHHHCC
>Mature Secondary Structure 
GNKNLLKRSIFKEKISELKSKKFSFEINRIQLPNGHEGEYGYIKHPGAALAVPITKDNK
CCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCEEECCCCEEEEEEECCCC
VIILRQYRFAVSRYLLEFPAGTLEIGETPINSIQREIQEETGFSANKWDELGTLVPAPGY
EEEEHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
ADEEIYLFLARDLNKLNYKVEGDLDEDIEVLILDPDELDNLISSGDEILDAKTVTAWFRA
CCCCEEEEEEHHHHHCCEEECCCCCCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHH
KQFLDKL
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]