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The map label for this gene is yggV [C]

Identifier: 123967839

GI number: 123967839

Start: 278999

End: 279613

Strand: Direct

Name: yggV [C]

Synonym: A9601_03021

Alternate gene names: 123967839

Gene position: 278999-279613 (Clockwise)

Preceding gene: 123967838

Following gene: 123967843

Centisome position: 16.71

GC content: 32.36

Gene sequence:

>615_bases
GTGGGGGCAAGAATTTATAAATTTGGCAAGAAAATAAGGATGAAAAATTTATATTTAGCGAGTAAGAATAAAGGTAAAAT
TGAAGAATATAAGAAATTGCTCGCTGGAGTTAATTGTAAATTGTTACTCCAGCCAGAATCATTAGAAGTTGAAGAGGATG
GACTGACATTTAGAGATAATGCAATTAAAAAAGCGAGAGAAGTTTCGAGAAAAACGAATAATTTTTCGATTGCAGATGAT
TCAGGAATTTGTATTGAAGCACTAGGTGGTAAGCCTGGCATTTACTCATCTAGATATGCAGAAAATGATCAGAAGAGAAT
TGAACGAGTTTTAAGAGAACTTGATGGAGTTCAAAATAGAAGTGCTTTCTTTATTGCTAATATTTGTGTCTGTTCCCCAA
ATGGTGAAGTGATAATTGAATCTGAGGCCAAATGTCATGGAAATATTATTTTAAACCCCAGAGGGAAAAGTGGTTTTGGG
TATGACCCAATTTTTGAGGAGAGTTCTACCGGATTAACTTTCGCAGAAATGAATAATGATATTAAAGACTCTTGTAGTCA
TAGAGGTAAAGCATTAAAAAAAATTATTCCAGATTTAATTGAAATTTTTTCTTAA

Upstream 100 bases:

>100_bases
ATAAAAATTTTTGGCTTCTTTTTAGGTTTTCAGGAACGGAACCTCTTTTAAGGTTATATTGTGAAGCACCAAAAGAATCT
TATCTAATTGAGGTATTAGA

Downstream 100 bases:

>100_bases
ATTCAATTGACCCAAGATCCATGAAGGCCATGAGGAATTGAAATGGGTAATTCATAAACAGCTAATTCTTTTAAGTCTTT
TGCGTCTAATATCACTAAAT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MGARIYKFGKKIRMKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGLTFRDNAIKKAREVSRKTNNFSIADD
SGICIEALGGKPGIYSSRYAENDQKRIERVLRELDGVQNRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKSGFG
YDPIFEESSTGLTFAEMNNDIKDSCSHRGKALKKIIPDLIEIFS

Sequences:

>Translated_204_residues
MGARIYKFGKKIRMKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGLTFRDNAIKKAREVSRKTNNFSIADD
SGICIEALGGKPGIYSSRYAENDQKRIERVLRELDGVQNRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKSGFG
YDPIFEESSTGLTFAEMNNDIKDSCSHRGKALKKIIPDLIEIFS
>Mature_203_residues
GARIYKFGKKIRMKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGLTFRDNAIKKAREVSRKTNNFSIADDS
GICIEALGGKPGIYSSRYAENDQKRIERVLRELDGVQNRSAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKSGFGY
DPIFEESSTGLTFAEMNNDIKDSCSHRGKALKKIIPDLIEIFS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=184, Percent_Identity=27.7173913043478, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=39.1752577319588, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17556833, Length=184, Percent_Identity=27.7173913043478, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=120, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920712, Length=178, Percent_Identity=30.3370786516854, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22786; Mature: 22655

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARIYKFGKKIRMKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGLTFRDN
CCCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHH
AIKKAREVSRKTNNFSIADDSGICIEALGGKPGIYSSRYAENDQKRIERVLRELDGVQNR
HHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCC
SAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKSGFGYDPIFEESSTGLTFAEMNND
CEEEEEEEEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEHHHHCCC
IKDSCSHRGKALKKIIPDLIEIFS
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GARIYKFGKKIRMKNLYLASKNKGKIEEYKKLLAGVNCKLLLQPESLEVEEDGLTFRDN
CCHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHH
AIKKAREVSRKTNNFSIADDSGICIEALGGKPGIYSSRYAENDQKRIERVLRELDGVQNR
HHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCC
SAFFIANICVCSPNGEVIIESEAKCHGNIILNPRGKSGFGYDPIFEESSTGLTFAEMNND
CEEEEEEEEEECCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEHHHHCCC
IKDSCSHRGKALKKIIPDLIEIFS
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]