Click here to switch to the map view.

The map label for this gene is glmM [H]

Identifier: 123967838

GI number: 123967838

Start: 277581

End: 279035

Strand: Direct

Name: glmM [H]

Synonym: A9601_03011

Alternate gene names: 123967838

Gene position: 277581-279035 (Clockwise)

Preceding gene: 123967836

Following gene: 123967839

Centisome position: 16.62

GC content: 30.58

Gene sequence:

>1455_bases
TTGAGAGCTGATAAATTAGATAAGATAAAATTTGGAACTGATGGTTGGAGAGGAATTATTGGTTTTGACTTTAACCTGTC
CAATCTTTCAAGAGTTGTTGTAGCTGCATGTCAGGAGTTACATTATCAATACTATAAAGAAGTTAATTCAAAGAAAATTA
TTATTGGATATGATCGTAGATTTATGGCTTGTGAATTCGCCAAGCAAATAGTGCCCTTTGTAAGAGGATGTGGTTTCGAA
CCGATCTTATCTGATGGCTTTGTTACAACGCCCTCTTGTAGCTTCTATGCCAAAGAAGTCGGTTGTCTTGGAGCGTTAGT
AATTACAGCAAGTCATAATCCATATAATTGGCTAGGTCTGAAAATAAAGAGCTTAAATGGATGTTCTGTTGACGAATCTT
TTACAAGAGAAGTTGAAAAAAGATTAATGCTTGGAAATTCAATTGAAAAAATAGATGGTATTACTCAGTTGGTAGATATT
AAGAAATTTCATTTAGATAGAATTAAATCCCTTTTTGATATTAACTATATTTCCAAGAGATTAAAAAAAATGAAATTGAA
AATTTTTGTAGATTCTATGCATGGTTCAGCTGCAAATTGTATGGCTGAGATTTTTGCTTCTAATGATTTAGAGGTTATTT
CAGAAATCAGGAAAGATGCTGATCCTTTTTTTGGAGGAAAACCTCCTGAACCTCTTCTGAATTATGCAGATGATCTAAAA
CAAACACTAATGAAAAATTCAACAAATGAAGTGAAAACTTTAGGAATTATATTTGATGGTGATGGTGATAGAATTGCGGC
AATTGATGAAAAAGGAAGATACTCTAGTACTCAAGATTTACTCCCATACTTTATTAAATATTTGGGCGAAATTAAAAATA
ATTCTTATCCAGTTTTAAAGACAGTTAGTGGTTCAGATATTATTAAAAATATTTCAGAGAGTCAAAATAGAGATGTTTTT
GAACTTCCGGTTGGCTTTAAATATATTGCTGAAAAAATGATTAAAGGAAAAATATTTATTGGAGGAGAGGAATCTGGGGG
AGTTGGTTTTGGTGACTTTATGCCTGAAAGAGATGCTCTATATGCAGCAATGGTTTTACTAAATGGAATTGCTGAAAAAT
CTCAATATTTATATGAAACTTTAGATGAAATTCAAGAAGACTTTGGGCCAAGTTTTTATAAAAGAATTGATATTAAATTT
CCAAATCAGTCAGAAAAAAATAACGTAAAAGAATTTATCATAGATAATATTCCTGAGAATATTAATAATCACAAGTTAAA
AAGTATCTCAAAGATCGATGGAATAAAATTGAGAATTGATAAAAATTTTTGGCTTCTTTTTAGGTTTTCAGGAACGGAAC
CTCTTTTAAGGTTATATTGTGAAGCACCAAAAGAATCTTATCTAATTGAGGTATTAGAGTGGGGGCAAGAATTTATAAAT
TTGGCAAGAAAATAA

Upstream 100 bases:

>100_bases
TTTAAATGAAGAGAATTCAAATTATTTTTTAAGGGCGGTTTTAAAATTTACTCATATAAATTAGTATAGATAATTAGAAG
AAATCAAGGAAATTTGAAAT

Downstream 100 bases:

>100_bases
GGATGAAAAATTTATATTTAGCGAGTAAGAATAAAGGTAAAATTGAAGAATATAAGAAATTGCTCGCTGGAGTTAATTGT
AAATTGTTACTCCAGCCAGA

Product: phosphotransferase superclass

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MRADKLDKIKFGTDGWRGIIGFDFNLSNLSRVVVAACQELHYQYYKEVNSKKIIIGYDRRFMACEFAKQIVPFVRGCGFE
PILSDGFVTTPSCSFYAKEVGCLGALVITASHNPYNWLGLKIKSLNGCSVDESFTREVEKRLMLGNSIEKIDGITQLVDI
KKFHLDRIKSLFDINYISKRLKKMKLKIFVDSMHGSAANCMAEIFASNDLEVISEIRKDADPFFGGKPPEPLLNYADDLK
QTLMKNSTNEVKTLGIIFDGDGDRIAAIDEKGRYSSTQDLLPYFIKYLGEIKNNSYPVLKTVSGSDIIKNISESQNRDVF
ELPVGFKYIAEKMIKGKIFIGGEESGGVGFGDFMPERDALYAAMVLLNGIAEKSQYLYETLDEIQEDFGPSFYKRIDIKF
PNQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLIEVLEWGQEFIN
LARK

Sequences:

>Translated_484_residues
MRADKLDKIKFGTDGWRGIIGFDFNLSNLSRVVVAACQELHYQYYKEVNSKKIIIGYDRRFMACEFAKQIVPFVRGCGFE
PILSDGFVTTPSCSFYAKEVGCLGALVITASHNPYNWLGLKIKSLNGCSVDESFTREVEKRLMLGNSIEKIDGITQLVDI
KKFHLDRIKSLFDINYISKRLKKMKLKIFVDSMHGSAANCMAEIFASNDLEVISEIRKDADPFFGGKPPEPLLNYADDLK
QTLMKNSTNEVKTLGIIFDGDGDRIAAIDEKGRYSSTQDLLPYFIKYLGEIKNNSYPVLKTVSGSDIIKNISESQNRDVF
ELPVGFKYIAEKMIKGKIFIGGEESGGVGFGDFMPERDALYAAMVLLNGIAEKSQYLYETLDEIQEDFGPSFYKRIDIKF
PNQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLIEVLEWGQEFIN
LARK
>Mature_484_residues
MRADKLDKIKFGTDGWRGIIGFDFNLSNLSRVVVAACQELHYQYYKEVNSKKIIIGYDRRFMACEFAKQIVPFVRGCGFE
PILSDGFVTTPSCSFYAKEVGCLGALVITASHNPYNWLGLKIKSLNGCSVDESFTREVEKRLMLGNSIEKIDGITQLVDI
KKFHLDRIKSLFDINYISKRLKKMKLKIFVDSMHGSAANCMAEIFASNDLEVISEIRKDADPFFGGKPPEPLLNYADDLK
QTLMKNSTNEVKTLGIIFDGDGDRIAAIDEKGRYSSTQDLLPYFIKYLGEIKNNSYPVLKTVSGSDIIKNISESQNRDVF
ELPVGFKYIAEKMIKGKIFIGGEESGGVGFGDFMPERDALYAAMVLLNGIAEKSQYLYETLDEIQEDFGPSFYKRIDIKF
PNQSEKNNVKEFIIDNIPENINNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLIEVLEWGQEFIN
LARK

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=475, Percent_Identity=24.4210526315789, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI290463102, Length=482, Percent_Identity=24.0663900414938, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI133922562, Length=480, Percent_Identity=23.9583333333333, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI290463104, Length=330, Percent_Identity=24.8484848484848, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1789566, Length=477, Percent_Identity=24.9475890985325, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788361, Length=448, Percent_Identity=24.1071428571429, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535441, Length=523, Percent_Identity=23.9005736137667, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323752, Length=398, Percent_Identity=26.1306532663317, Blast_Score=106, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6322722, Length=388, Percent_Identity=26.2886597938144, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17864244, Length=536, Percent_Identity=24.4402985074627, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24651977, Length=432, Percent_Identity=24.3055555555556, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129809, Length=432, Percent_Identity=24.3055555555556, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24653722, Length=432, Percent_Identity=23.1481481481481, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 55066; Mature: 55066

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADKLDKIKFGTDGWRGIIGFDFNLSNLSRVVVAACQELHYQYYKEVNSKKIIIGYDRR
CCCCCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
FMACEFAKQIVPFVRGCGFEPILSDGFVTTPSCSFYAKEVGCLGALVITASHNPYNWLGL
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCCEEEEE
KIKSLNGCSVDESFTREVEKRLMLGNSIEKIDGITQLVDIKKFHLDRIKSLFDINYISKR
EEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKMKLKIFVDSMHGSAANCMAEIFASNDLEVISEIRKDADPFFGGKPPEPLLNYADDLK
HHHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
QTLMKNSTNEVKTLGIIFDGDGDRIAAIDEKGRYSSTQDLLPYFIKYLGEIKNNSYPVLK
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
TVSGSDIIKNISESQNRDVFELPVGFKYIAEKMIKGKIFIGGEESGGVGFGDFMPERDAL
ECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCEEEECCCCCCCCCCHHCCCCHHHH
YAAMVLLNGIAEKSQYLYETLDEIQEDFGPSFYKRIDIKFPNQSEKNNVKEFIIDNIPEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHHHHHHCCCCC
INNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLIEVLEWGQEFIN
CCCHHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LARK
HHCC
>Mature Secondary Structure
MRADKLDKIKFGTDGWRGIIGFDFNLSNLSRVVVAACQELHYQYYKEVNSKKIIIGYDRR
CCCCCCCCEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCH
FMACEFAKQIVPFVRGCGFEPILSDGFVTTPSCSFYAKEVGCLGALVITASHNPYNWLGL
HHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCCEEEEE
KIKSLNGCSVDESFTREVEKRLMLGNSIEKIDGITQLVDIKKFHLDRIKSLFDINYISKR
EEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKMKLKIFVDSMHGSAANCMAEIFASNDLEVISEIRKDADPFFGGKPPEPLLNYADDLK
HHHHHHEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
QTLMKNSTNEVKTLGIIFDGDGDRIAAIDEKGRYSSTQDLLPYFIKYLGEIKNNSYPVLK
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
TVSGSDIIKNISESQNRDVFELPVGFKYIAEKMIKGKIFIGGEESGGVGFGDFMPERDAL
ECCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCEEEECCCCCCCCCCHHCCCCHHHH
YAAMVLLNGIAEKSQYLYETLDEIQEDFGPSFYKRIDIKFPNQSEKNNVKEFIIDNIPEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHHHHHHCCCCC
INNHKLKSISKIDGIKLRIDKNFWLLFRFSGTEPLLRLYCEAPKESYLIEVLEWGQEFIN
CCCHHHHHHHHCCCEEEEEECCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
LARK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]