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The map label for this gene is obgE [H]

Identifier: 123967775

GI number: 123967775

Start: 222845

End: 223828

Strand: Direct

Name: obgE [H]

Synonym: A9601_02381

Alternate gene names: 123967775

Gene position: 222845-223828 (Clockwise)

Preceding gene: 123967774

Following gene: 123967776

Centisome position: 13.34

GC content: 34.76

Gene sequence:

>984_bases
GTGCAATTTATTGATCAAGCGAACATTATTCTTAAAGCTGGAAAAGGTGGCAATGGAATAGTTTCATTTAGAAGAGAAAA
ATTCGTTCCTGCTGGAGGACCTTCGGGGGGGAATGGTGGTAGAGGGGGTTCAGTTATTTTGATGGCTGATAATAATCTAC
AAACATTATTAGATTTCAAATTCAAACGTGAAATAATTGCTGAAGATGGATGCAAAGGAGGTCCTAATAAGAGATCAGGT
GCTTCAGGTGAGGATACAATCCTTAAAGTACCATGCGGAACAGAAATCAGGGATATTAAAACCGGCATTATTTTAGGAGA
CTTAACTAAACATAAACAGAGTTTAACTATTGCCATTGGAGGAAGAGGTGGACATGGTAATGCATACTATTTAAGTAATC
AAAATAGAGCCCCAGAATCATTCACTGAAGGAAAAGATGGTGAGATATGGGAGGTTCAATTAGAACTAAAACTTCTTGCA
GAAGTTGGGATTATAGGTCTTCCAAATGCTGGGAAAAGTACCTTGATTTCTGTTGTATCATCTGCCCGTCCAAAAATCGC
AAATTATCCTTTCACAACTCTAATACCTAACTTAGGTGTAGTAAGAAAAATTGATGGGAATGGTTGCCTTTTTGCGGATA
TTCCTGGATTAATATCAGGGGCAGCTGATGGAGTAGGTTTAGGCCATGATTTTTTAAGGCATATCCAAAGAACGAAGATA
CTTGTTCACTTAATTGATGCAATTGCAGAAAATCCTTTACATGATTTTGAGATAATTGAGCAGGAATTAAAAAAATATGG
AAAAGGTCTTTTAGATAAAGAGAGGATAATAGTATTGAATAAAATCGAGCTGGTAGATGATGATTATCTGAAAATAATTT
CAAAAAAGTTAGAAGATTTATCTAAAAAGAAAGTTTTAGTTATTTCTTCATCTTTAAAAAAAGGTTTATCTTCACTGCTT
TCTGAAGTATGGAAAAGGATTTAA

Upstream 100 bases:

>100_bases
ATTGAAGATGCAGCCAACAACGAGGGTGGCCCTGGTTGCAGTATTGCGTGGATAAAATAAAATTTAAAATACCTAGAAAA
CAATTTAATAAACGTATTAA

Downstream 100 bases:

>100_bases
CTTAAATTAAAATTTTTTTGTAAAAAAAAACACTTGATTTAATAATGAAAATTAGTCATAAATAAGATACCTCTTTAAAC
ACAATATGAATTTCTATACT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDIKTGIILGDLTKHKQSLTIAIGGRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVVSSARPKIANYPFTTLIPNLGVVRKIDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKIELVDDDYLKIISKKLEDLSKKKVLVISSSLKKGLSSLL
SEVWKRI

Sequences:

>Translated_327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDIKTGIILGDLTKHKQSLTIAIGGRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVVSSARPKIANYPFTTLIPNLGVVRKIDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKIELVDDDYLKIISKKLEDLSKKKVLVISSSLKKGLSSLL
SEVWKRI
>Mature_327_residues
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFKFKREIIAEDGCKGGPNKRSG
ASGEDTILKVPCGTEIRDIKTGIILGDLTKHKQSLTIAIGGRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLA
EVGIIGLPNAGKSTLISVVSSARPKIANYPFTTLIPNLGVVRKIDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
LVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKIELVDDDYLKIISKKLEDLSKKKVLVISSSLKKGLSSLL
SEVWKRI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=318, Percent_Identity=37.4213836477987, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI111955139, Length=286, Percent_Identity=33.5664335664336, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI111955063, Length=178, Percent_Identity=35.9550561797753, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4758796, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789574, Length=332, Percent_Identity=47.5903614457831, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787454, Length=128, Percent_Identity=35.9375, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=283, Percent_Identity=38.86925795053, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=29.320987654321, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17509631, Length=172, Percent_Identity=31.9767441860465, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=159, Percent_Identity=40.251572327044, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=109, Percent_Identity=38.5321100917431, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129375, Length=325, Percent_Identity=35.3846153846154, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24585318, Length=293, Percent_Identity=35.8361774744027, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24640873, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640877, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640875, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356473, Length=108, Percent_Identity=36.1111111111111, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 35296; Mature: 35296

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFK
CCCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FKREIIAEDGCKGGPNKRSGASGEDTILKVPCGTEIRDIKTGIILGDLTKHKQSLTIAIG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCEEEECCCCCCCEEEEEEE
GRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLAEVGIIGLPNAGKSTLISVVS
CCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIANYPFTTLIPNLGVVRKIDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
HCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKIELVDDDYLKIISKKLEDL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
SKKKVLVISSSLKKGLSSLLSEVWKRI
HHCEEEEEHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQFIDQANIILKAGKGGNGIVSFRREKFVPAGGPSGGNGGRGGSVILMADNNLQTLLDFK
CCCCCCCCEEEEECCCCCCEEEEHHHHCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHH
FKREIIAEDGCKGGPNKRSGASGEDTILKVPCGTEIRDIKTGIILGDLTKHKQSLTIAIG
HHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHCCEEEECCCCCCCEEEEEEE
GRGGHGNAYYLSNQNRAPESFTEGKDGEIWEVQLELKLLAEVGIIGLPNAGKSTLISVVS
CCCCCCCEEEECCCCCCCCHHCCCCCCCEEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIANYPFTTLIPNLGVVRKIDGNGCLFADIPGLISGAADGVGLGHDFLRHIQRTKI
HCCCCCCCCCHHHHCCCCCEEEEECCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LVHLIDAIAENPLHDFEIIEQELKKYGKGLLDKERIIVLNKIELVDDDYLKIISKKLEDL
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHH
SKKKVLVISSSLKKGLSSLLSEVWKRI
HHCEEEEEHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA