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The map label for this gene is trxB [H]

Identifier: 123967766

GI number: 123967766

Start: 214785

End: 215741

Strand: Direct

Name: trxB [H]

Synonym: A9601_02291

Alternate gene names: 123967766

Gene position: 214785-215741 (Clockwise)

Preceding gene: 123967763

Following gene: 123967769

Centisome position: 12.86

GC content: 37.51

Gene sequence:

>957_bases
TTGGAAATCATTGAGTCAGATGTAGTTATTATCGGAGGAGGCCCGGCCGGATGTACTTGCGCACTTTATACATCTCGTTC
AAACTTAAAGACAGTAATTTTAGATAAAAATCCATCTGTTGGCGCCTTAGCAATAACTCATCAAATAGCTAATTATCCAG
GTGTTCCGGTTGATATAAGTGGAGAGAAATTACTTACTCTAATGAGAGATCAGGCTGTGCAATACGGCACAGATTATAGA
AGAGCGCAAGTGTTTGGAATAGATGCTACTGGAGAATGGAAAATGGTTTATACGCCCGAAGGCACTTTCAAAGCTAAAGC
ACTTGTGCTTGCAAGTGGAGCCATGGGTAGGCCTGCATCATTTAAGGGCGAAGCGGATTTTCTTGGCAAAGGAGTAAGTT
ATTGTGCTACATGTGATGGGGCCTTTTATAAAAATAGAGAAGTTGCCGTTGTTGGAGTGAACAAGGAGGCAATTGAAGAG
GCAACTGTTCTAACTAAATTTGCATCTACTGTGCATTGGATTACATCAAGTGATCCTAAATCAGATAATGAAGAAGCTAT
GGAATTGATGGATAATTCAAATATAAAACATTGGAGTAGAACAAGATTATTAGAAATATTGGGCGATGATTTGGGTGTGA
ATGGGGTTGTTGTAAAAAATAAACAAGAAGAAAATCCTATCAATTTAAATTTAGATGGAGTGTTTGTCTACATGAGTGGC
TCAAAGCCGATTACTGATTTTTTAGGTGATCAAATTGCTTTAAAAGAAGACGGAGGAGTTATTGTTGATGACTTTATGTC
TACAAACTCTGATGGAGTATGGGCTATTGGAGATATAAGAAATACACCATTTAAGCAAGCCGTAGTTGCGGCTTCTGATG
GATGTATTGCTGCAATGTCAATTGATAGATACTTAAATAGTCGAAAAAATATAAGAGTAGATTGGATTCATTCTTAA

Upstream 100 bases:

>100_bases
TTTAACTTATATCTATATAAAGGTTCAGGTATTTACTTTAAAAATATCTTCTAACCAAAAACTCATCTAATTTACTACTA
AAAAAAGGAGTTTTTTAAAA

Downstream 100 bases:

>100_bases
AAAGAATATTTCTTCTTGAATTTAAAGGGGTGTTGCTTCAGAAATATAAGCCACTCCTCCGTAGTAGCTTAAATCGTCCC
TGATGTTATCTCTCATTTTA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMRDQAVQYGTDYR
RAQVFGIDATGEWKMVYTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELMDNSNIKHWSRTRLLEILGDDLGVNGVVVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKEDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS

Sequences:

>Translated_318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMRDQAVQYGTDYR
RAQVFGIDATGEWKMVYTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELMDNSNIKHWSRTRLLEILGDDLGVNGVVVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKEDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS
>Mature_318_residues
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDISGEKLLTLMRDQAVQYGTDYR
RAQVFGIDATGEWKMVYTPEGTFKAKALVLASGAMGRPASFKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEE
ATVLTKFASTVHWITSSDPKSDNEEAMELMDNSNIKHWSRTRLLEILGDDLGVNGVVVKNKQEENPINLNLDGVFVYMSG
SKPITDFLGDQIALKEDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMSIDRYLNSRKNIRVDWIHS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=35.4632587859425, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87081763, Length=305, Percent_Identity=29.5081967213115, Blast_Score=107, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6321898, Length=324, Percent_Identity=32.0987654320988, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=30.4347826086957, Blast_Score=155, Evalue=1e-38,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34443; Mature: 34443

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDIS
CCEECCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEHHHCCCCCEEEEC
GEKLLTLMRDQAVQYGTDYRRAQVFGIDATGEWKMVYTPEGTFKAKALVLASGAMGRPAS
CHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEEATVLTKFASTVHWITSSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDNEEAMELMDNSNIKHWSRTRLLEILGDDLGVNGVVVKNKQEENPINLNLDGVFVYMSG
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECEEEEEEEC
SKPITDFLGDQIALKEDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMS
CCCHHHHCCCEEEEECCCCEEEEHHHCCCCCCEEEEECCCCCCHHHEEEEECCCEEEEEE
IDRYLNSRKNIRVDWIHS
HHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MEIIESDVVIIGGGPAGCTCALYTSRSNLKTVILDKNPSVGALAITHQIANYPGVPVDIS
CCEECCCEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEEEHHHCCCCCEEEEC
GEKLLTLMRDQAVQYGTDYRRAQVFGIDATGEWKMVYTPEGTFKAKALVLASGAMGRPAS
CHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCCCCCCCC
FKGEADFLGKGVSYCATCDGAFYKNREVAVVGVNKEAIEEATVLTKFASTVHWITSSDPK
CCCCHHHHCCCCCEEEECCCCEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEEECCCCC
SDNEEAMELMDNSNIKHWSRTRLLEILGDDLGVNGVVVKNKQEENPINLNLDGVFVYMSG
CCCHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEECEEEEEEEC
SKPITDFLGDQIALKEDGGVIVDDFMSTNSDGVWAIGDIRNTPFKQAVVAASDGCIAAMS
CCCHHHHCCCEEEEECCCCEEEEHHHCCCCCCEEEEECCCCCCHHHEEEEECCCEEEEEE
IDRYLNSRKNIRVDWIHS
HHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]