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The map label for this gene is purE [H]

Identifier: 123967722

GI number: 123967722

Start: 171588

End: 172079

Strand: Reverse

Name: purE [H]

Synonym: A9601_01851

Alternate gene names: 123967722

Gene position: 172079-171588 (Counterclockwise)

Preceding gene: 123967724

Following gene: 123967719

Centisome position: 10.3

GC content: 34.35

Gene sequence:

>492_bases
ATGGGTAGTGATTCAGATCTAAAAACATTGAAGCCATCCATTGATATTTTAAGAGAATTTGGAATAAAAACTGAAGTTTG
TATACTTTCCGCTCATCGAACACCTATTGAAATGATGGAATATGCAAAAAATGCAGAATCAGAAAACATAAAAGTAATAA
TTGCCGGTGCTGGGGGTGCTGCTCATCTTCCAGGAATGCTAGCATCTATAACTTGCATTCCTGTAATTGGTGTACCAGTA
GAGAGTAAGACACTTAAGGGGATTGACTCTCTTTTATCAATCGTACAAATGCCCGCTGGAATTCCAGTTGCAACAGTTGC
AATTAATGGAGGTCAAAATGCTGGATTATTGGCAATAGAGATGATCAGTTTATTTGACGAATCCATAAAGAAAAATTTGA
AAGAATTCAGAGAAAATCTACATACAAAGGTAAGAACTAAAAATAGTAAGTTATCAAATATTGGACCTGACAATTATCTT
CAAAATAAATGA

Upstream 100 bases:

>100_bases
CTAACTGGCGCCAAATTAATTGCACGCCATTATAGGAAAGAATTGATTTGTTATTTTGTCAGAATTGAATTCTAAAGATA
TTTATAAAATTGCTGTCGTA

Downstream 100 bases:

>100_bases
ACTAATATTTTTCTATTATGCCTTGTTAAGAAAGTTTTCTTTTTTAAGGTAGTTAATAATTTTTTCAACGGAATCATTTA
ATTCTAACGAACCTGTATCA

Product: phosphoribosylaminoimidazole carboxylase

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MGSDSDLKTLKPSIDILREFGIKTEVCILSAHRTPIEMMEYAKNAESENIKVIIAGAGGAAHLPGMLASITCIPVIGVPV
ESKTLKGIDSLLSIVQMPAGIPVATVAINGGQNAGLLAIEMISLFDESIKKNLKEFRENLHTKVRTKNSKLSNIGPDNYL
QNK

Sequences:

>Translated_163_residues
MGSDSDLKTLKPSIDILREFGIKTEVCILSAHRTPIEMMEYAKNAESENIKVIIAGAGGAAHLPGMLASITCIPVIGVPV
ESKTLKGIDSLLSIVQMPAGIPVATVAINGGQNAGLLAIEMISLFDESIKKNLKEFRENLHTKVRTKNSKLSNIGPDNYL
QNK
>Mature_162_residues
GSDSDLKTLKPSIDILREFGIKTEVCILSAHRTPIEMMEYAKNAESENIKVIIAGAGGAAHLPGMLASITCIPVIGVPVE
SKTLKGIDSLLSIVQMPAGIPVATVAINGGQNAGLLAIEMISLFDESIKKNLKEFRENLHTKVRTKNSKLSNIGPDNYLQ
NK

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=106, Percent_Identity=53.7735849056604, Blast_Score=121, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324702, Length=163, Percent_Identity=52.1472392638037, Blast_Score=171, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17483; Mature: 17351

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSDSDLKTLKPSIDILREFGIKTEVCILSAHRTPIEMMEYAKNAESENIKVIIAGAGGA
CCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCH
AHLPGMLASITCIPVIGVPVESKTLKGIDSLLSIVQMPAGIPVATVAINGGQNAGLLAIE
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHH
MISLFDESIKKNLKEFRENLHTKVRTKNSKLSNIGPDNYLQNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GSDSDLKTLKPSIDILREFGIKTEVCILSAHRTPIEMMEYAKNAESENIKVIIAGAGGA
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEEECCCH
AHLPGMLASITCIPVIGVPVESKTLKGIDSLLSIVQMPAGIPVATVAINGGQNAGLLAIE
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHH
MISLFDESIKKNLKEFRENLHTKVRTKNSKLSNIGPDNYLQNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]