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The map label for this gene is trpB [H]

Identifier: 123967719

GI number: 123967719

Start: 169302

End: 170546

Strand: Reverse

Name: trpB [H]

Synonym: A9601_01821

Alternate gene names: 123967719

Gene position: 170546-169302 (Counterclockwise)

Preceding gene: 123967722

Following gene: 123967717

Centisome position: 10.21

GC content: 38.15

Gene sequence:

>1245_bases
GTGGTAAGTACATTTTCTCGCAAAGATCAAAACTATAAAAATGACGATTTAAATCAACCCTCCATAGAGGGAAGATTTGG
AAAATATGGTGGTCAATATGTTCCTGAAACGCTAATGCCCGCTCTTTTTGAGCTTGAAGACGCTGCGTCTAATGCATGGA
AAGATAAACTTTTTGTAGAAGAATTGAATCACCTACTCAAGACTTATGTAGGAAGAGAAACACCACTTTATGAAGCCAAA
AGACTTACTGAACATTACAAAAATAAACAAGCAACTCCTAGGATATGGCTTAAAAGAGAAGATTTAAATCATACTGGGGC
TCACAAAATTAATAATGCTCTTGGACAAGCTTTATTGGCAATAAGAATGGGCAAAAAAAGAATAATTGCAGAAACTGGAG
CAGGTCAGCACGGAGTTGCTACTGCTACTGTTTGTGCGAGATTTGGCTTGAAATGTATTATCTACATGGGTGCTGAAGAT
ATAAAAAGGCAATCCCTTAACGTTTTCAGAATGAAACTTTTAGGAGCTGAAGTTAAAGTTGTAAATTCTGGAACTGCAAC
ACTTAAGGATGCTACTAGTGAGGCCATTAGAGATTGGGTTTCTAATGTCGAAACCACACACTACATTTTAGGATCTGTTG
CAGGCCCACACCCTTTCCCAAAGATTGTGCGCGATTTTCATGCAGTTATAGGTGAAGAAACTAAAAAACAATGTTTGGAA
TCATTTGGATCTTTACCCGATATTTTGCTTGCTTGTGTAGGTGGAGGATCAAATGCAATGGGGCTTTTCCATCCTTTTGT
TAAAGAAACTTCTGTGCGGCTTATTGGAGTTGAAGCCGCAGGAAGCGGAGTTGATACTGACAAACATGCTGCCACTATCA
CTAAAGGGTCAGTTGGAATTTTGCATGGATCAATGAGTCTTCTCTTGCAAGATGATAATGGTCAAGTACAAGAAGCTCAC
TCAATAAGTGCAGGTTTAGATTACCCTGGAGTAGGTCCTGAACATAGCCATTTAAAAGATATAGGCAGAGCAGAATATGG
ATCAGTCACAGATCAAGAAGCTTTGGACGCTTTAAAACTTGTTAGTGAACTAGAAGGAATTATACCTGCACTTGAAACTG
CCCATGCTTTTGCTTGGTTAGATAAATTATGCCCTACTCTTGAAAAAGATACTAATATAGTAATCAATTGCTCTGGTAGA
GGCGACAAAGATGTTAATACTGTTGCATCTTCATTAGATATTTAA

Upstream 100 bases:

>100_bases
CTTCAGATTTCTTTTCTTGATTATCAAATTCGATCCAATTCTTTTTTCCCATTATTTTCAATATAATCTATAGTTAGTTA
ATACTTATTCTATAGAAAAA

Downstream 100 bases:

>100_bases
TCAATACCTTGGGATTGATGGGTCAATATATCTACTCCATCCATCAATACCCTCCTCCAAATTCCATATTTCGCTCACAA
TATTATTATCCAAGCACCAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MVSTFSRKDQNYKNDDLNQPSIEGRFGKYGGQYVPETLMPALFELEDAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKNKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSLPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKDIGRAEYGSVTDQEALDALKLVSELEGIIPALETAHAFAWLDKLCPTLEKDTNIVINCSGR
GDKDVNTVASSLDI

Sequences:

>Translated_414_residues
MVSTFSRKDQNYKNDDLNQPSIEGRFGKYGGQYVPETLMPALFELEDAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKNKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSLPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKDIGRAEYGSVTDQEALDALKLVSELEGIIPALETAHAFAWLDKLCPTLEKDTNIVINCSGR
GDKDVNTVASSLDI
>Mature_414_residues
MVSTFSRKDQNYKNDDLNQPSIEGRFGKYGGQYVPETLMPALFELEDAASNAWKDKLFVEELNHLLKTYVGRETPLYEAK
RLTEHYKNKQATPRIWLKREDLNHTGAHKINNALGQALLAIRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAED
IKRQSLNVFRMKLLGAEVKVVNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
SFGSLPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGILHGSMSLLLQDDNGQVQEAH
SISAGLDYPGVGPEHSHLKDIGRAEYGSVTDQEALDALKLVSELEGIIPALETAHAFAWLDKLCPTLEKDTNIVINCSGR
GDKDVNTVASSLDI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=384, Percent_Identity=56.25, Blast_Score=434, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321412, Length=389, Percent_Identity=58.3547557840617, Blast_Score=469, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 45004; Mature: 45004

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTFSRKDQNYKNDDLNQPSIEGRFGKYGGQYVPETLMPALFELEDAASNAWKDKLFVE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELNHLLKTYVGRETPLYEAKRLTEHYKNKQATPRIWLKREDLNHTGAHKINNALGQALLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
IRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAEDIKRQSLNVFRMKLLGAEVKV
HHHCCHHEEEECCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
SFGSLPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGI
HHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHEEEECCCEEE
LHGSMSLLLQDDNGQVQEAHSISAGLDYPGVGPEHSHLKDIGRAEYGSVTDQEALDALKL
EECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
VSELEGIIPALETAHAFAWLDKLCPTLEKDTNIVINCSGRGDKDVNTVASSLDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MVSTFSRKDQNYKNDDLNQPSIEGRFGKYGGQYVPETLMPALFELEDAASNAWKDKLFVE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELNHLLKTYVGRETPLYEAKRLTEHYKNKQATPRIWLKREDLNHTGAHKINNALGQALLA
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
IRMGKKRIIAETGAGQHGVATATVCARFGLKCIIYMGAEDIKRQSLNVFRMKLLGAEVKV
HHHCCHHEEEECCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHCCEEEE
VNSGTATLKDATSEAIRDWVSNVETTHYILGSVAGPHPFPKIVRDFHAVIGEETKKQCLE
EECCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHH
SFGSLPDILLACVGGGSNAMGLFHPFVKETSVRLIGVEAAGSGVDTDKHAATITKGSVGI
HHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHEEEECCCEEE
LHGSMSLLLQDDNGQVQEAHSISAGLDYPGVGPEHSHLKDIGRAEYGSVTDQEALDALKL
EECCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHH
VSELEGIIPALETAHAFAWLDKLCPTLEKDTNIVINCSGRGDKDVNTVASSLDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA