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The map label for this gene is mpg1 [H]

Identifier: 123967706

GI number: 123967706

Start: 159244

End: 160422

Strand: Direct

Name: mpg1 [H]

Synonym: A9601_01691

Alternate gene names: 123967706

Gene position: 159244-160422 (Clockwise)

Preceding gene: 123967705

Following gene: 123967708

Centisome position: 9.54

GC content: 35.45

Gene sequence:

>1179_bases
ATGAAGGCAATGATACTTGCGGCAGGTAAAGGTACACGTGTTCAGCCTATTACTCATGTTATTCCGAAACCGATGATTCC
GATTTTACAAAAACCCGTTATGGAGTTTCTCTTGGAACTTTTAAGAGAACATAACTTTAAGGAAATAATGGTAAATGTTT
CTCATCTCGCTGAAGAAATTGAAAATTATTTTAGAGATGGGCAAAGATTTGGAGTAGAAATTGCTTATAGTTTTGAGGGA
AGAATTGAAGACGGGGAACTAATAGGTGATGCTTTGGGATCTGCAGGAGGATTAAAAAAAATTCAGGATTTTCAAAATTT
CTTTGATGAAACTTTTGTTGTGTTATGTGGTGATGCTTTAGTTGATTTAGATTTAACTCAAGCTGTTAAAAAACATAAGC
AGAAAGGAGCGATTGCGAGCTTGATAACAAAGAAGGTAACTAAAGATCAAGTATCAAGTTACGGTGTTGTAGTGTCTGAT
GAAAATGGGAGGATAAAGGCTTTTCAGGAAAAGCCAACAGTTGATCAAGCTTTAAGTGACTCTATAAATACAGGAATTTA
TCTTTTCGAACCCGAAATTTTTAATTACATACCTTCAGCAGAGAAATTTGATATTGGAGCTGATCTTTTCCCTAAACTTG
TTGAAATGGATTTACCATTTTTTGCATTACCAATGGATTTTGAATGGGTAGATATTGGAAAAGTTCCTGATTATTGGACT
GCCATCAGAAATGTATTACTAGGTAAGGTAAGACAAGTACAAATACCAGGTAAGGAAATAAAACCCGGAGTTTTTACTGG
CTTGAATGTAGCGGCTAACTGGGAAAAGGTTAATATTACCGGGCCGGTTTATATAGGAGGTATGACTAGGATCGAGGATG
GAGCAACTATTATTGGCCCTTCCATGATTGGACCAAGTTGTTGCATTTGCGAGGGCGCAACTATAGATAACTCAATTATT
TTTGATTATTCTAAAATTGGTAAAGGTGTAAGACTTATGGATAAGTTAGTGTTTGGTAAATATTGTGTTGGGAAAAATGG
AGATCATTTTGATTTGCAAGATGCATCTTTAGATTGGTTAATAGCTGATTCAAGAAGATCTGATTTGACTGAGCCATCGC
CTCAACAGAAAGCTATGGCAGAATTATTAGGTACTGATTTGATTAATATTCCAGACTAA

Upstream 100 bases:

>100_bases
AACTGCCTATAGAAAATCTTGAGGTAAGTAATGTCTCTTCCTCGGCTGCTTAGAAGCTTAATAGTAATAACGTATAATTT
TAAAAAATGGTTTTGAATTT

Downstream 100 bases:

>100_bases
GATTAGCTTTTTCAATAATCTCGGGAATTAAGTGCTCTGCTTTTACGGCCATTAAATGAACACCATTTGCGATATTCATA
AAATCATGAGCTTGTTCAGC

Product: putative sugar-phosphate nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKAMILAAGKGTRVQPITHVIPKPMIPILQKPVMEFLLELLREHNFKEIMVNVSHLAEEIENYFRDGQRFGVEIAYSFEG
RIEDGELIGDALGSAGGLKKIQDFQNFFDETFVVLCGDALVDLDLTQAVKKHKQKGAIASLITKKVTKDQVSSYGVVVSD
ENGRIKAFQEKPTVDQALSDSINTGIYLFEPEIFNYIPSAEKFDIGADLFPKLVEMDLPFFALPMDFEWVDIGKVPDYWT
AIRNVLLGKVRQVQIPGKEIKPGVFTGLNVAANWEKVNITGPVYIGGMTRIEDGATIIGPSMIGPSCCICEGATIDNSII
FDYSKIGKGVRLMDKLVFGKYCVGKNGDHFDLQDASLDWLIADSRRSDLTEPSPQQKAMAELLGTDLINIPD

Sequences:

>Translated_392_residues
MKAMILAAGKGTRVQPITHVIPKPMIPILQKPVMEFLLELLREHNFKEIMVNVSHLAEEIENYFRDGQRFGVEIAYSFEG
RIEDGELIGDALGSAGGLKKIQDFQNFFDETFVVLCGDALVDLDLTQAVKKHKQKGAIASLITKKVTKDQVSSYGVVVSD
ENGRIKAFQEKPTVDQALSDSINTGIYLFEPEIFNYIPSAEKFDIGADLFPKLVEMDLPFFALPMDFEWVDIGKVPDYWT
AIRNVLLGKVRQVQIPGKEIKPGVFTGLNVAANWEKVNITGPVYIGGMTRIEDGATIIGPSMIGPSCCICEGATIDNSII
FDYSKIGKGVRLMDKLVFGKYCVGKNGDHFDLQDASLDWLIADSRRSDLTEPSPQQKAMAELLGTDLINIPD
>Mature_392_residues
MKAMILAAGKGTRVQPITHVIPKPMIPILQKPVMEFLLELLREHNFKEIMVNVSHLAEEIENYFRDGQRFGVEIAYSFEG
RIEDGELIGDALGSAGGLKKIQDFQNFFDETFVVLCGDALVDLDLTQAVKKHKQKGAIASLITKKVTKDQVSSYGVVVSD
ENGRIKAFQEKPTVDQALSDSINTGIYLFEPEIFNYIPSAEKFDIGADLFPKLVEMDLPFFALPMDFEWVDIGKVPDYWT
AIRNVLLGKVRQVQIPGKEIKPGVFTGLNVAANWEKVNITGPVYIGGMTRIEDGATIIGPSMIGPSCCICEGATIDNSII
FDYSKIGKGVRLMDKLVFGKYCVGKNGDHFDLQDASLDWLIADSRRSDLTEPSPQQKAMAELLGTDLINIPD

Specific function: Glycogen biosynthesis; first step. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=351, Percent_Identity=28.2051282051282, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI11761619, Length=345, Percent_Identity=27.8260869565217, Blast_Score=122, Evalue=5e-28,
Organism=Escherichia coli, GI1789837, Length=383, Percent_Identity=21.9321148825065, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=369, Percent_Identity=30.6233062330623, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17509979, Length=356, Percent_Identity=25.561797752809, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509981, Length=346, Percent_Identity=24.8554913294798, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320148, Length=366, Percent_Identity=26.775956284153, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI21355443, Length=343, Percent_Identity=31.4868804664723, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24644084, Length=343, Percent_Identity=31.4868804664723, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 43399; Mature: 43399

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAMILAAGKGTRVQPITHVIPKPMIPILQKPVMEFLLELLREHNFKEIMVNVSHLAEEI
CCEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ENYFRDGQRFGVEIAYSFEGRIEDGELIGDALGSAGGLKKIQDFQNFFDETFVVLCGDAL
HHHHHCCHHCCEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCHH
VDLDLTQAVKKHKQKGAIASLITKKVTKDQVSSYGVVVSDENGRIKAFQEKPTVDQALSD
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCCHHHHHHH
SINTGIYLFEPEIFNYIPSAEKFDIGADLFPKLVEMDLPFFALPMDFEWVDIGKVPDYWT
HCCCCEEEECHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCEEEECCCCCHHHH
AIRNVLLGKVRQVQIPGKEIKPGVFTGLNVAANWEKVNITGPVYIGGMTRIEDGATIIGP
HHHHHHHCCCEEEECCCCCCCCCEEECCCEEECCEEEEECCCEEECCCEEECCCCEEECC
SMIGPSCCICEGATIDNSIIFDYSKIGKGVRLMDKLVFGKYCVGKNGDHFDLQDASLDWL
CCCCCCEEEECCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEE
IADSRRSDLTEPSPQQKAMAELLGTDLINIPD
EECCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKAMILAAGKGTRVQPITHVIPKPMIPILQKPVMEFLLELLREHNFKEIMVNVSHLAEEI
CCEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ENYFRDGQRFGVEIAYSFEGRIEDGELIGDALGSAGGLKKIQDFQNFFDETFVVLCGDAL
HHHHHCCHHCCEEEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCHH
VDLDLTQAVKKHKQKGAIASLITKKVTKDQVSSYGVVVSDENGRIKAFQEKPTVDQALSD
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCCHHHHHHH
SINTGIYLFEPEIFNYIPSAEKFDIGADLFPKLVEMDLPFFALPMDFEWVDIGKVPDYWT
HCCCCEEEECHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEECCCCCEEEECCCCCHHHH
AIRNVLLGKVRQVQIPGKEIKPGVFTGLNVAANWEKVNITGPVYIGGMTRIEDGATIIGP
HHHHHHHCCCEEEECCCCCCCCCEEECCCEEECCEEEEECCCEEECCCEEECCCCEEECC
SMIGPSCCICEGATIDNSIIFDYSKIGKGVRLMDKLVFGKYCVGKNGDHFDLQDASLDWL
CCCCCCEEEECCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHEECCCCCCCCCCCCCEEEE
IADSRRSDLTEPSPQQKAMAELLGTDLINIPD
EECCCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]