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The map label for this gene is ubiB [C]

Identifier: 123967138

GI number: 123967138

Start: 1700465

End: 1702321

Strand: Direct

Name: ubiB [C]

Synonym: P9515_19051

Alternate gene names: 123967138

Gene position: 1700465-1702321 (Clockwise)

Preceding gene: 123967134

Following gene: 123967139

Centisome position: 99.78

GC content: 30.48

Gene sequence:

>1857_bases
ATGAACGAAGATTATACAGATTTTATAGAAGCTTCGGGATTACTTGAATATAATCCAGAAATAATTTCTAAAATTTATCA
AAAAAACCCTAGTCGACTATTCAAAAGACTTTGGCAAACTCTAATCCCAATTTTTGTATATATAATTTCAGTCGGGTGGG
ATAAATTAACTGGACAACTAAAAAAAGAATCTAAAGCTAGATATAGAGCAAAGCAACTAACAAATTTATTAGTAGAATTA
GGCCCTGCATTTGTTAAAGCTGGTCAAGCTTTATCAACCAGACCAGACATTATTCCTAGTGTTCTTCTAGAAGAGTTATC
TGAGCTTCAAGATCAATTACCAGGATTTGATGGAGATAAAGCGATGGAACTTATAGAAGAAGATTTGAATAAAGAAATTG
ATGAGATTTTTTTAACTATTGATAAAGAACCAATTTCTGCAGCATCTTTAGGACAAGTTCATAAAGCTGTTCTCAAAAAT
AAAGATGTTGTGGCTGTAAAAGTACAAAGACCTGGGTTAAGAGAACAAATCACACTTGATTTATACATAGTTAGAAATAT
TGCTAATTGGTTGAAAAATAATATTGGACTAATTAGGAGCGATCTTGTTGCTTTGATTGATGAATTAGGAAAAAGAGTTT
TTGAAGAAATGGATTATCTAAACGAAGCTGAAAATGCTGAAAAATTTAGAAATTTTCATCTACATAACTCAAAAATTGCT
GTGCCAAAAATTTATAAAGAAACCACTTCACGAAGAGTGTTAACTATGGAATGGATAGATGGCACAAAGCTCACAAATCT
CGAAGAGGTTAAAAATTTAGGTATAGATCCTGACGAGATGATTGAAATAGGAGTGCAATGTAGTTTAGAGCAATTATTAG
AACATGGTTTCTTTCATGCTGACCCACATCCTGGCAATTTATTAGCCTTGAAAGATGGCAGATTATGCTATTTGGATTTC
GGTATGATGAGTGAAGTTACTAAAACATCTAGATCCGGATTAATCCAAGCAGTAGTTCATCTTGTTAATAAGAATTTTGA
TAAATTATCTCAAGATTTTGTTAAGTTAGGTTTCTTATCTGAAGAAGTTAATCTTGAACCTATTGTTCCAGCTTTTCAAG
ATGTCTTTATAAATGCAGTAGAACTTGGTGTGTCGAAAATGGATTTTAAAAGTGTAACTGATGATATGTCAGGAGTTATG
TATAAATTTCCTTTTAAATTACCTCCATATTATGCACTTATAATTAGGTCTTTATTAACATTAGAAGGGATTGCTTTAAG
CGTAGATCCTGATTTTAAAATACTCGGAGCAGCTTATCCATATTTCGCCCGAAGATTAATGGAAGACCCTGATCCTCAAC
TAAGAGAAAGTTTAAAAGAAATGCTTTTTGATAATAAAAAATTCAAATGGGACAGATTAGAAGATTTACTATCTAACGCA
GCAAAACAGACCAATCTCAATTTAGAAAAACTTCTTGATGAAGTTATTAATCTTCTTTTTTCTCCGAAAGGTGGATTTCT
AAGAAATGAAATTATTAATAGTTTGACTGATCAAATAGACTTAGTAGGTTTAAAATTACTGAAGGGTGTAAATAATTACC
TTCCAAAATCAATTAAATTAAACATTGCAAAAGATAACGAAAACATTAATGATTTAATTTTAACAATTGAGCCTTTCAAA
AATTTTCTAGAAATCATACAAAAAATACCTGGATACTCTATTGATATTTTTCTAAAAAGAGTTCCAAGACTTATAAACGA
ACCTTACACAAAAGAAATGAGTTTAACAATTGCAAAAAAAGTTACAGAAAAAAGCGTTGTCAGACTTGTAAAAATTGCTG
CTGGTGTAACTATATAA

Upstream 100 bases:

>100_bases
CAATATTTTTTAATTTTAATTGTATTAACATGATAATTCTTACATACAAAAAAATTAACTTCTTTTTGAAGAAAATAAAA
GGGTTTAAATAAATAAAGTT

Downstream 100 bases:

>100_bases
ATGAAATTTTCTAAAAGTTTGCTTTCTAAAATTTTTTTAATAATAATTACTAATCACATTTTTTTAAATCCACCTAAAGT
TCAATCTGCAGAAAATATCA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MNEDYTDFIEASGLLEYNPEIISKIYQKNPSRLFKRLWQTLIPIFVYIISVGWDKLTGQLKKESKARYRAKQLTNLLVEL
GPAFVKAGQALSTRPDIIPSVLLEELSELQDQLPGFDGDKAMELIEEDLNKEIDEIFLTIDKEPISAASLGQVHKAVLKN
KDVVAVKVQRPGLREQITLDLYIVRNIANWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAENAEKFRNFHLHNSKIA
VPKIYKETTSRRVLTMEWIDGTKLTNLEEVKNLGIDPDEMIEIGVQCSLEQLLEHGFFHADPHPGNLLALKDGRLCYLDF
GMMSEVTKTSRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVELGVSKMDFKSVTDDMSGVM
YKFPFKLPPYYALIIRSLLTLEGIALSVDPDFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLNLEKLLDEVINLLFSPKGGFLRNEIINSLTDQIDLVGLKLLKGVNNYLPKSIKLNIAKDNENINDLILTIEPFK
NFLEIIQKIPGYSIDIFLKRVPRLINEPYTKEMSLTIAKKVTEKSVVRLVKIAAGVTI

Sequences:

>Translated_618_residues
MNEDYTDFIEASGLLEYNPEIISKIYQKNPSRLFKRLWQTLIPIFVYIISVGWDKLTGQLKKESKARYRAKQLTNLLVEL
GPAFVKAGQALSTRPDIIPSVLLEELSELQDQLPGFDGDKAMELIEEDLNKEIDEIFLTIDKEPISAASLGQVHKAVLKN
KDVVAVKVQRPGLREQITLDLYIVRNIANWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAENAEKFRNFHLHNSKIA
VPKIYKETTSRRVLTMEWIDGTKLTNLEEVKNLGIDPDEMIEIGVQCSLEQLLEHGFFHADPHPGNLLALKDGRLCYLDF
GMMSEVTKTSRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVELGVSKMDFKSVTDDMSGVM
YKFPFKLPPYYALIIRSLLTLEGIALSVDPDFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLNLEKLLDEVINLLFSPKGGFLRNEIINSLTDQIDLVGLKLLKGVNNYLPKSIKLNIAKDNENINDLILTIEPFK
NFLEIIQKIPGYSIDIFLKRVPRLINEPYTKEMSLTIAKKVTEKSVVRLVKIAAGVTI
>Mature_618_residues
MNEDYTDFIEASGLLEYNPEIISKIYQKNPSRLFKRLWQTLIPIFVYIISVGWDKLTGQLKKESKARYRAKQLTNLLVEL
GPAFVKAGQALSTRPDIIPSVLLEELSELQDQLPGFDGDKAMELIEEDLNKEIDEIFLTIDKEPISAASLGQVHKAVLKN
KDVVAVKVQRPGLREQITLDLYIVRNIANWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAENAEKFRNFHLHNSKIA
VPKIYKETTSRRVLTMEWIDGTKLTNLEEVKNLGIDPDEMIEIGVQCSLEQLLEHGFFHADPHPGNLLALKDGRLCYLDF
GMMSEVTKTSRSGLIQAVVHLVNKNFDKLSQDFVKLGFLSEEVNLEPIVPAFQDVFINAVELGVSKMDFKSVTDDMSGVM
YKFPFKLPPYYALIIRSLLTLEGIALSVDPDFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
AKQTNLNLEKLLDEVINLLFSPKGGFLRNEIINSLTDQIDLVGLKLLKGVNNYLPKSIKLNIAKDNENINDLILTIEPFK
NFLEIIQKIPGYSIDIFLKRVPRLINEPYTKEMSLTIAKKVTEKSVVRLVKIAAGVTI

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=304, Percent_Identity=31.25, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI41393593, Length=287, Percent_Identity=30.3135888501742, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI217035081, Length=234, Percent_Identity=31.1965811965812, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI27363457, Length=324, Percent_Identity=28.7037037037037, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI217416386, Length=288, Percent_Identity=28.8194444444444, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI34147522, Length=303, Percent_Identity=29.042904290429, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI2367309, Length=407, Percent_Identity=26.044226044226, Blast_Score=155, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17559152, Length=268, Percent_Identity=33.2089552238806, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32565180, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323282, Length=240, Percent_Identity=33.75, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325148, Length=462, Percent_Identity=22.0779220779221, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321319, Length=261, Percent_Identity=27.5862068965517, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI22024280, Length=285, Percent_Identity=31.2280701754386, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24662575, Length=278, Percent_Identity=31.6546762589928, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859849, Length=259, Percent_Identity=27.7992277992278, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 70405; Mature: 70405

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50011 PROTEIN_KINASE_DOM ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDYTDFIEASGLLEYNPEIISKIYQKNPSRLFKRLWQTLIPIFVYIISVGWDKLTGQL
CCCCHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KKESKARYRAKQLTNLLVELGPAFVKAGQALSTRPDIIPSVLLEELSELQDQLPGFDGDK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLNKEIDEIFLTIDKEPISAASLGQVHKAVLKNKDVVAVKVQRPGLREQITLD
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
LYIVRNIANWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAENAEKFRNFHLHNSKIA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VPKIYKETTSRRVLTMEWIDGTKLTNLEEVKNLGIDPDEMIEIGVQCSLEQLLEHGFFHA
CHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
DPHPGNLLALKDGRLCYLDFGMMSEVTKTSRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EEVNLEPIVPAFQDVFINAVELGVSKMDFKSVTDDMSGVMYKFPFKLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPDFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLNLEKLLDEVINLLFSPKGGFLRNEIINSLTDQIDLVGLKLLKGVNNYLPKSIKL
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NIAKDNENINDLILTIEPFKNFLEIIQKIPGYSIDIFLKRVPRLINEPYTKEMSLTIAKK
EEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
VTEKSVVRLVKIAAGVTI
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNEDYTDFIEASGLLEYNPEIISKIYQKNPSRLFKRLWQTLIPIFVYIISVGWDKLTGQL
CCCCHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
KKESKARYRAKQLTNLLVELGPAFVKAGQALSTRPDIIPSVLLEELSELQDQLPGFDGDK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHH
AMELIEEDLNKEIDEIFLTIDKEPISAASLGQVHKAVLKNKDVVAVKVQRPGLREQITLD
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
LYIVRNIANWLKNNIGLIRSDLVALIDELGKRVFEEMDYLNEAENAEKFRNFHLHNSKIA
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VPKIYKETTSRRVLTMEWIDGTKLTNLEEVKNLGIDPDEMIEIGVQCSLEQLLEHGFFHA
CHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
DPHPGNLLALKDGRLCYLDFGMMSEVTKTSRSGLIQAVVHLVNKNFDKLSQDFVKLGFLS
CCCCCCEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
EEVNLEPIVPAFQDVFINAVELGVSKMDFKSVTDDMSGVMYKFPFKLPPYYALIIRSLLT
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHH
LEGIALSVDPDFKILGAAYPYFARRLMEDPDPQLRESLKEMLFDNKKFKWDRLEDLLSNA
HCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AKQTNLNLEKLLDEVINLLFSPKGGFLRNEIINSLTDQIDLVGLKLLKGVNNYLPKSIKL
HHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
NIAKDNENINDLILTIEPFKNFLEIIQKIPGYSIDIFLKRVPRLINEPYTKEMSLTIAKK
EEECCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHH
VTEKSVVRLVKIAAGVTI
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]