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The map label for this gene is mraY

Identifier: 123967134

GI number: 123967134

Start: 1692868

End: 1693959

Strand: Direct

Name: mraY

Synonym: P9515_19011

Alternate gene names: 123967134

Gene position: 1692868-1693959 (Clockwise)

Preceding gene: 123967133

Following gene: 123967138

Centisome position: 99.34

GC content: 24.45

Gene sequence:

>1092_bases
ATGATTCATCAGAAGATGATTGGGAAGACTAGAAGACTAGATTTTACTACTTTATTTTTTTTAATTACATTATCTTTAAT
AGTAAATTCTTTTATTTTTAATAATTTACTTATAATTTGTATTTTTCTTGTATTTTTTTCTATTTGTATATTAATAACTA
ATTACGGTTTAAAAATAATTAAACAATTAAATTTACTACAAAATATTAGAGATACAGGACCATCTTTTCATTTTAATAAA
AAGAATACACCTACAATGGGAGGAATATTTATTATTCTTCCTTTATTATTACTGCTTTTAATAGTAAACCATTACTTCTA
TTCCATGGGAATAATACTATTATTTTTTGGTAGTTTAAGTTTTTTTATTATAGGATTTTTAGACGACTATTTAAGTATTA
AGAAGAAAAAGAATATAGGTTTAAGATCAACTCAAAAATTCATATTACAATCATTAATTTCAATATTATTTATCGTATTA
GCCTATCAAAATGGTTATATAAACTCTTTAATTACAGTATCCAATAATTGGGCTATTGATACTAATATAGTGATTTTTCC
AATCTGTTTTGTTACCTTAGTAGGTTTAAGTAACGCAGTAAATTTAACAGACGGACTTGATGGATTAGCATCTGGATGCG
GGTCAATAGTCTTTTATGGACTTGGCACAGAAATATTTATTAAAGGTCAGCAAGAATTAATAATATATGGTCTTATTGCG
TACGCAATGTCAGGTTTATGTGTAGGCTTTTTGAAATTTAATAAGTATCCTGCAAAAATATTCATGGGCGATACAGGATC
ATTAACAATTGGTGCAACATTAGGTTATATTTCAATATTAACTAATAGCTATTTTACATTATTTATTATCTCAGGAATAT
TTGTTATTGAAGCTTTATCAGTAATTATTCAAGTAAGTTTTTTTAAAATAACCAAAAAAATATTTAAAAGAGGAAAAAGG
GTCTTTTTAATGACTCCAATACATCATCATTTTGAATTGAGTGGAATGAAGGAAGAAAAAATAGTTGAAAACTTCTGGAA
AATCAACATATTACTCGTAATTTTAGGTATAGTTTTAAAAATAAATCTTTAA

Upstream 100 bases:

>100_bases
CTTGTAACTGAAAAAGATGGAGACTCACAAGAAATTAGTACAATTGAAGAGGAAGAACTTTCAGCTTTAATGGGAGAAAA
AGAGGATTATAAAACCGAAG

Downstream 100 bases:

>100_bases
AGCATTACTTAATATGAGTTTCTTTACATGGAAAGATGATGGATTAACAAGTGACTGTAGTAGTCTTGATGCGATGGCTT
CTAGATTTGAAGAAACAGCT

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKIIKQLNLLQNIRDTGPSFHFNK
KNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLSFFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVL
AYQNGYINSLITVSNNWAIDTNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIA
YAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALSVIIQVSFFKITKKIFKRGKR
VFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLKINL

Sequences:

>Translated_363_residues
MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKIIKQLNLLQNIRDTGPSFHFNK
KNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLSFFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVL
AYQNGYINSLITVSNNWAIDTNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIA
YAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALSVIIQVSFFKITKKIFKRGKR
VFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLKINL
>Mature_363_residues
MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKIIKQLNLLQNIRDTGPSFHFNK
KNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLSFFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVL
AYQNGYINSLITVSNNWAIDTNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIA
YAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALSVIIQVSFFKITKKIFKRGKR
VFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLKINL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=358, Percent_Identity=35.195530726257, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1790218, Length=301, Percent_Identity=26.9102990033223, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PROM5 (A2BZ97)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001012215.1
- STRING:   A2BZ97
- GeneID:   4720134
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_19011
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   HHSFELH
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40938; Mature: 40938

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b3ef988)-; HASH(0x1ad653a4)-; HASH(0x1b59b73c)-; HASH(0x1b3ef934)-; HASH(0x1b66820c)-; HASH(0x1a8ba3e8)-; HASH(0x1ae1c4d8)-; HASH(0x1a4bce10)-; HASH(0x1aeb1374)-; HASH(0x1b8570b0)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKII
CCCHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLNLLQNIRDTGPSFHFNKKNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLS
HHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVLAYQNGYINSLITVSNNWAID
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
TNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIA
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEEECCCEEEEECCHHHHHHHHHH
YAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALS
HHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VIIQVSFFKITKKIFKRGKRVFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLK
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
INL
CCH
>Mature Secondary Structure
MIHQKMIGKTRRLDFTTLFFLITLSLIVNSFIFNNLLIICIFLVFFSICILITNYGLKII
CCCHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLNLLQNIRDTGPSFHFNKKNTPTMGGIFIILPLLLLLLIVNHYFYSMGIILLFFGSLS
HHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFIIGFLDDYLSIKKKKNIGLRSTQKFILQSLISILFIVLAYQNGYINSLITVSNNWAID
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEE
TNIVIFPICFVTLVGLSNAVNLTDGLDGLASGCGSIVFYGLGTEIFIKGQQELIIYGLIA
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHEEEEECCCEEEEECCHHHHHHHHHH
YAMSGLCVGFLKFNKYPAKIFMGDTGSLTIGATLGYISILTNSYFTLFIISGIFVIEALS
HHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VIIQVSFFKITKKIFKRGKRVFLMTPIHHHFELSGMKEEKIVENFWKINILLVILGIVLK
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
INL
CCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA