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The map label for this gene is ruvB

Identifier: 123967037

GI number: 123967037

Start: 1589665

End: 1590723

Strand: Reverse

Name: ruvB

Synonym: P9515_18041

Alternate gene names: 123967037

Gene position: 1590723-1589665 (Counterclockwise)

Preceding gene: 123967039

Following gene: 123967036

Centisome position: 93.34

GC content: 31.73

Gene sequence:

>1059_bases
ATGGCAATAATTTCTTCAAGTTTAGATGAATCTAATATTCCTCGCTCAAGAAAAGAGTTGAGGTTAGTTGATTCAAAGAT
AATTGCTGATGAAAAAATAAATAAGAATTTAAATATAGTTCGGCCAACTTCTTTTAAAGAATTTATTGGACAAGAGCAAA
TTAAATCTTCATTAAAAATAGCTATAGATGCTTCTAAATATAGGAAAGAAGCACTAGAACATACACTTTTATATGGTCAA
CCAGGGTTAGGAAAAACTACTTTAGCGTTATTGATTTCTTATGAAATGAATTCAAAATGTAGAGTGGCAAGCGCACCTTC
AATTGAAAGACCAAGGGATATTGTGGGATTACTTCTTGGATTAAAAGAAGGAGAGATTTTATTCATTGATGAAATACATC
GTTTAAACAAATTAACTGAAGAGCTTTTATATTCTGCAATGGAAGATTTTAGGCTGGATTTAACAATGGGAGCTAATAGA
GGGGCTCGCTGCAGAACAATAAATCTACCGAAATTTACTTTGATCGGGGCCACAACAAAACTCGCATCAATTAGTGCTCC
ACTCAGAGATAGATTTGGACTATGTCATAAAATTGAATTTTATTCAAATGATGAATTGAAACAAATAATTTTTAATTTTT
CTAATTTGATAAACCTTCAGTTGGACAGTGATGCGTGCTGCTCGCTAGCCAAGATCTCAAGAGGAACTCCAAGAATTGCA
TTGCGATTATTAAAAAGAGTTAGAGATTATGCTCAGGTTATGAAAAAGACTAATAAAATTTCCATTGAGATTATCGAAAA
AGCTTTAGATTCTCAAAAAATTGATAATAGAGGATTGGATAATGTAGATAGGAAATTCTTGTCTTTTTTGAAACTTAATA
ATAATAATCCGATTGGCTTAGATTCAATTGCTGCAGGTATGGGCGAGGAATCTTCAATGTTAGAGTTTGTAGTTGAGCCA
TATTTAATTCAAATTGGGTTTATTATGAGAACTCCTCGAGGAAGAAAACTTACATCTTTAGGGAAAAAGTATATTAGTTC
CAACAATGAAAAGTACTAA

Upstream 100 bases:

>100_bases
GGCTTCTTTTTTGTTGCTTTTATTTGATTTGTTTGAAACTTTTGCAATCATAGTTGTAAAAAATCTTTCCCCAAAGAACA
ATTGCCATTAATCTTTAATT

Downstream 100 bases:

>100_bases
AAAGATTAAGCCTTATTTTTTATTGATTTGTTTTTTGATTAATATCTTATGTGTTTCGCCAAGTTTTTCGTTAAGTTCAA
AGGAAAATTTTTTTAAAAAT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAIISSSLDESNIPRSRKELRLVDSKIIADEKINKNLNIVRPTSFKEFIGQEQIKSSLKIAIDASKYRKEALEHTLLYGQ
PGLGKTTLALLISYEMNSKCRVASAPSIERPRDIVGLLLGLKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANR
GARCRTINLPKFTLIGATTKLASISAPLRDRFGLCHKIEFYSNDELKQIIFNFSNLINLQLDSDACCSLAKISRGTPRIA
LRLLKRVRDYAQVMKKTNKISIEIIEKALDSQKIDNRGLDNVDRKFLSFLKLNNNNPIGLDSIAAGMGEESSMLEFVVEP
YLIQIGFIMRTPRGRKLTSLGKKYISSNNEKY

Sequences:

>Translated_352_residues
MAIISSSLDESNIPRSRKELRLVDSKIIADEKINKNLNIVRPTSFKEFIGQEQIKSSLKIAIDASKYRKEALEHTLLYGQ
PGLGKTTLALLISYEMNSKCRVASAPSIERPRDIVGLLLGLKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANR
GARCRTINLPKFTLIGATTKLASISAPLRDRFGLCHKIEFYSNDELKQIIFNFSNLINLQLDSDACCSLAKISRGTPRIA
LRLLKRVRDYAQVMKKTNKISIEIIEKALDSQKIDNRGLDNVDRKFLSFLKLNNNNPIGLDSIAAGMGEESSMLEFVVEP
YLIQIGFIMRTPRGRKLTSLGKKYISSNNEKY
>Mature_351_residues
AIISSSLDESNIPRSRKELRLVDSKIIADEKINKNLNIVRPTSFKEFIGQEQIKSSLKIAIDASKYRKEALEHTLLYGQP
GLGKTTLALLISYEMNSKCRVASAPSIERPRDIVGLLLGLKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANRG
ARCRTINLPKFTLIGATTKLASISAPLRDRFGLCHKIEFYSNDELKQIIFNFSNLINLQLDSDACCSLAKISRGTPRIAL
RLLKRVRDYAQVMKKTNKISIEIIEKALDSQKIDNRGLDNVDRKFLSFLKLNNNNPIGLDSIAAGMGEESSMLEFVVEPY
LIQIGFIMRTPRGRKLTSLGKKYISSNNEKY

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=301, Percent_Identity=46.5116279069767, Blast_Score=292, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PROM5 (A2BZ00)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001012118.1
- ProteinModelPortal:   A2BZ00
- SMR:   A2BZ00
- STRING:   A2BZ00
- GeneID:   4719973
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_18041
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   PMAR167542:P9515ORF_1885-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 39763; Mature: 39632

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIISSSLDESNIPRSRKELRLVDSKIIADEKINKNLNIVRPTSFKEFIGQEQIKSSLKI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHCHHHHHHHHEE
AIDASKYRKEALEHTLLYGQPGLGKTTLALLISYEMNSKCRVASAPSIERPRDIVGLLLG
EEEHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCHHHHHHHHHC
LKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANRGARCRTINLPKFTLIGATTK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCEEEEECHHH
LASISAPLRDRFGLCHKIEFYSNDELKQIIFNFSNLINLQLDSDACCSLAKISRGTPRIA
HHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHCCCCHHHH
LRLLKRVRDYAQVMKKTNKISIEIIEKALDSQKIDNRGLDNVDRKFLSFLKLNNNNPIGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCH
DSIAAGMGEESSMLEFVVEPYLIQIGFIMRTPRGRKLTSLGKKYISSNNEKY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AIISSSLDESNIPRSRKELRLVDSKIIADEKINKNLNIVRPTSFKEFIGQEQIKSSLKI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHCHHHHHHHHEE
AIDASKYRKEALEHTLLYGQPGLGKTTLALLISYEMNSKCRVASAPSIERPRDIVGLLLG
EEEHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCHHHHHHHHHC
LKEGEILFIDEIHRLNKLTEELLYSAMEDFRLDLTMGANRGARCRTINLPKFTLIGATTK
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEECCCCEEEEECHHH
LASISAPLRDRFGLCHKIEFYSNDELKQIIFNFSNLINLQLDSDACCSLAKISRGTPRIA
HHHCCCCHHHHCCCEEEEEECCCCHHHHHHHHHHHHEEEEECCHHHHHHHHHCCCCHHHH
LRLLKRVRDYAQVMKKTNKISIEIIEKALDSQKIDNRGLDNVDRKFLSFLKLNNNNPIGL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCH
DSIAAGMGEESSMLEFVVEPYLIQIGFIMRTPRGRKLTSLGKKYISSNNEKY
HHHHHCCCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA