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The map label for this gene is pheA [H]

Identifier: 123966917

GI number: 123966917

Start: 1480955

End: 1481800

Strand: Direct

Name: pheA [H]

Synonym: P9515_16841

Alternate gene names: 123966917

Gene position: 1480955-1481800 (Clockwise)

Preceding gene: 123966915

Following gene: 123966925

Centisome position: 86.9

GC content: 32.98

Gene sequence:

>846_bases
ATGCGCAAACAAGTTGCATATTTGGGCCCTGAAGGGACATACGCAGAAAAAGCAGCTCATATTTTATCAGAGCTTGCCAA
TTTTGAGTCACCTTTATTTGTACCATGTAATGGGCTATATTCGGTTATTAAAGCAATAGCCTACAACAATTGTGATGCAG
CAATAGTGCCTATTGAAAACTCGGTTGAGGGAGGAGTAACAACTACTTTAGACGCACTTTGGAAATTTTCGGATATTAAT
ATCAATAGAGCAATTGTTTTGCCAATAAAACATGCATTAATAAGTGATGGAGATATTTCGGAAATATCAGAAGTACTTTC
TCATCCACAAGCTTTAGCTCAATGTTCTGAATGGCTATCTGAGAATCTTCCAGAGGCTATTACTTTATCAACTAATTCAA
CTTCCGAAGCAGTGAAAATGGTAAAAGGGAGTTCATTTAGAGCAGCTATTGGATCGAAATCTCTTACTGAAATTGAAGGA
CTTAAAGAACTAGCATTCCCCATTAATGATGTTCCAGGGAATTGTACAAGATTTGTTTTATTAAGTAAAGAATCGATTTT
AGATAAAGCTAATATTGCCAGTTTTGCCTTTTCATTGCTCTCAAATAATCCTGGAGCTTTACTTGAAGCTTTAAATTATA
TTTCAGATTTTGGATTCAATATGAGTAAAATAGAATCTAGGCCTTCTAAAAGAGAACTAGGAGAATATATCATTTACATT
GATGTTGATATAAATACAAGAACTAATATTGAAGCGTTCTATGAATTGAAGAAAAAATTAAAACCCTTATGTGAACATTT
GGTAGACTTTGGATGTTATTTATCAGAAAAGATTAAATTAGATTAA

Upstream 100 bases:

>100_bases
TTGTTACAGAAAGTTTAAGTTTCTGTTTAGCATCAAAAGCTAAAAGCATTTTTCTATATACCTCCAATGCTTAATTGATC
TTTTTTTTTTACAATTAATC

Downstream 100 bases:

>100_bases
TTAACCTCTACATTTATAAACTCCAAATTCCATTAAACCTTTTTTAAAAGCCCAATCCATTAACAATATTGTAGGAATCT
CTCTTACAGACTTTACTAAT

Product: chorismate mutase-prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRKQVAYLGPEGTYAEKAAHILSELANFESPLFVPCNGLYSVIKAIAYNNCDAAIVPIENSVEGGVTTTLDALWKFSDIN
INRAIVLPIKHALISDGDISEISEVLSHPQALAQCSEWLSENLPEAITLSTNSTSEAVKMVKGSSFRAAIGSKSLTEIEG
LKELAFPINDVPGNCTRFVLLSKESILDKANIASFAFSLLSNNPGALLEALNYISDFGFNMSKIESRPSKRELGEYIIYI
DVDINTRTNIEAFYELKKKLKPLCEHLVDFGCYLSEKIKLD

Sequences:

>Translated_281_residues
MRKQVAYLGPEGTYAEKAAHILSELANFESPLFVPCNGLYSVIKAIAYNNCDAAIVPIENSVEGGVTTTLDALWKFSDIN
INRAIVLPIKHALISDGDISEISEVLSHPQALAQCSEWLSENLPEAITLSTNSTSEAVKMVKGSSFRAAIGSKSLTEIEG
LKELAFPINDVPGNCTRFVLLSKESILDKANIASFAFSLLSNNPGALLEALNYISDFGFNMSKIESRPSKRELGEYIIYI
DVDINTRTNIEAFYELKKKLKPLCEHLVDFGCYLSEKIKLD
>Mature_281_residues
MRKQVAYLGPEGTYAEKAAHILSELANFESPLFVPCNGLYSVIKAIAYNNCDAAIVPIENSVEGGVTTTLDALWKFSDIN
INRAIVLPIKHALISDGDISEISEVLSHPQALAQCSEWLSENLPEAITLSTNSTSEAVKMVKGSSFRAAIGSKSLTEIEG
LKELAFPINDVPGNCTRFVLLSKESILDKANIASFAFSLLSNNPGALLEALNYISDFGFNMSKIESRPSKRELGEYIIYI
DVDINTRTNIEAFYELKKKLKPLCEHLVDFGCYLSEKIKLD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=284, Percent_Identity=30.9859154929577, Blast_Score=114, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6324013, Length=322, Percent_Identity=27.3291925465839, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 30876; Mature: 30876

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKQVAYLGPEGTYAEKAAHILSELANFESPLFVPCNGLYSVIKAIAYNNCDAAIVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCEEEEECCC
SVEGGVTTTLDALWKFSDININRAIVLPIKHALISDGDISEISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPEAITLSTNSTSEAVKMVKGSSFRAAIGSKSLTEIEGLKELAFPINDVPGNCTRFVL
CCCCCEEEEECCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
LSKESILDKANIASFAFSLLSNNPGALLEALNYISDFGFNMSKIESRPSKRELGEYIIYI
ECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DVDINTRTNIEAFYELKKKLKPLCEHLVDFGCYLSEKIKLD
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKQVAYLGPEGTYAEKAAHILSELANFESPLFVPCNGLYSVIKAIAYNNCDAAIVPIEN
CCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCCCEEEEECCC
SVEGGVTTTLDALWKFSDININRAIVLPIKHALISDGDISEISEVLSHPQALAQCSEWLS
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHH
ENLPEAITLSTNSTSEAVKMVKGSSFRAAIGSKSLTEIEGLKELAFPINDVPGNCTRFVL
CCCCCEEEEECCCHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
LSKESILDKANIASFAFSLLSNNPGALLEALNYISDFGFNMSKIESRPSKRELGEYIIYI
ECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCEEEEE
DVDINTRTNIEAFYELKKKLKPLCEHLVDFGCYLSEKIKLD
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]