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The map label for this gene is rpiA [H]

Identifier: 123966902

GI number: 123966902

Start: 1463495

End: 1464190

Strand: Reverse

Name: rpiA [H]

Synonym: P9515_16691

Alternate gene names: 123966902

Gene position: 1464190-1463495 (Counterclockwise)

Preceding gene: 123966903

Following gene: 123966900

Centisome position: 85.92

GC content: 35.2

Gene sequence:

>696_bases
ATGAAACAAATAGTTGCTGATGCAGCTGTTAAAGAGGTGAAAGATGGAATGATCGTAGGTTTAGGGTCTGGTTCAACTGC
AGCACTCATGATAAAAAGCCTTGCTGAACAAATCAGATTAGGCAAATTAAAAAATATTAAAGGAGTTCCAACTTCTTTTC
AGTCTGAGGTTCTTTCTCTAGAACTTAAGATTCCATTAATTGATTTAGCTTCAGTTTCCCAAATTGATTTAGCTATTGAT
GGGGCAGATGAAGTGGATCCTGATTTTCAGTTAATCAAGGGAGGTGGAGCCTGCCATGTCCGAGAAAAATTGGTTGCATC
TAAAGCAAATAAATTATTAATAGTTGTTGATGAAACTAAATTAGTGCAACAATTAAACTTAGTTTTTCCTCTACCTGTAG
AGGTTCTACCTTCTGCTTGGAAGCAGGTGAAGGATATAATTTCTGAAATGAATGGAGTTTCTGATTTGAGGATGGCAACA
AAAAAAGCAGGACCTGTTGTCACGGATCAAGGTAATTTGATTTTGGATGTCTTATTTAATACTGGTATCAAAGATCCAAA
AGATTTAGAAATGCGTATTAATAATATTCCTGGAGTATTGGAAAATGGATTGTTTGTTAATTTAACAGATAAGGTTTTGG
TGGGTAAGATTGAGAACAATGTTCCAGTGTTATTTTCACCTTCCAAGGGGAGTTAA

Upstream 100 bases:

>100_bases
TATTAAACCTGAAGCACTTCCAGGTTTGACATAAATCATTTGTTGAAATTTAATAATCTATAAACTTTACGCTAAAAACA
TTTTGGATTTACAGACTCAG

Downstream 100 bases:

>100_bases
TCCTCAAATCTAATTTTTACTGAATTCGCATGACTATGGAGACCTTCGCTGTTTGCCAAGTTTATAATATCTGAGCTATT
GATTTTTAAACTTTTTTCAT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKQIVADAAVKEVKDGMIVGLGSGSTAALMIKSLAEQIRLGKLKNIKGVPTSFQSEVLSLELKIPLIDLASVSQIDLAID
GADEVDPDFQLIKGGGACHVREKLVASKANKLLIVVDETKLVQQLNLVFPLPVEVLPSAWKQVKDIISEMNGVSDLRMAT
KKAGPVVTDQGNLILDVLFNTGIKDPKDLEMRINNIPGVLENGLFVNLTDKVLVGKIENNVPVLFSPSKGS

Sequences:

>Translated_231_residues
MKQIVADAAVKEVKDGMIVGLGSGSTAALMIKSLAEQIRLGKLKNIKGVPTSFQSEVLSLELKIPLIDLASVSQIDLAID
GADEVDPDFQLIKGGGACHVREKLVASKANKLLIVVDETKLVQQLNLVFPLPVEVLPSAWKQVKDIISEMNGVSDLRMAT
KKAGPVVTDQGNLILDVLFNTGIKDPKDLEMRINNIPGVLENGLFVNLTDKVLVGKIENNVPVLFSPSKGS
>Mature_231_residues
MKQIVADAAVKEVKDGMIVGLGSGSTAALMIKSLAEQIRLGKLKNIKGVPTSFQSEVLSLELKIPLIDLASVSQIDLAID
GADEVDPDFQLIKGGGACHVREKLVASKANKLLIVVDETKLVQQLNLVFPLPVEVLPSAWKQVKDIISEMNGVSDLRMAT
KKAGPVVTDQGNLILDVLFNTGIKDPKDLEMRINNIPGVLENGLFVNLTDKVLVGKIENNVPVLFSPSKGS

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=230, Percent_Identity=40.4347826086956, Blast_Score=160, Evalue=8e-40,
Organism=Escherichia coli, GI1789280, Length=218, Percent_Identity=41.2844036697248, Blast_Score=127, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17551758, Length=215, Percent_Identity=39.0697674418605, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324669, Length=235, Percent_Identity=37.0212765957447, Blast_Score=135, Evalue=4e-33,
Organism=Drosophila melanogaster, GI281364072, Length=215, Percent_Identity=42.3255813953488, Blast_Score=147, Evalue=7e-36,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 24756; Mature: 24756

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIVADAAVKEVKDGMIVGLGSGSTAALMIKSLAEQIRLGKLKNIKGVPTSFQSEVLSL
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEE
ELKIPLIDLASVSQIDLAIDGADEVDPDFQLIKGGGACHVREKLVASKANKLLIVVDETK
EEECCEEECCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCHH
LVQQLNLVFPLPVEVLPSAWKQVKDIISEMNGVSDLRMATKKAGPVVTDQGNLILDVLFN
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCEEEEEEEC
TGIKDPKDLEMRINNIPGVLENGLFVNLTDKVLVGKIENNVPVLFSPSKGS
CCCCCCCHHHEEECCCCCHHHCCEEEEEECCEEEEEECCCCCEEECCCCCC
>Mature Secondary Structure
MKQIVADAAVKEVKDGMIVGLGSGSTAALMIKSLAEQIRLGKLKNIKGVPTSFQSEVLSL
CCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEEE
ELKIPLIDLASVSQIDLAIDGADEVDPDFQLIKGGGACHVREKLVASKANKLLIVVDETK
EEECCEEECCCCCEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEEECCHH
LVQQLNLVFPLPVEVLPSAWKQVKDIISEMNGVSDLRMATKKAGPVVTDQGNLILDVLFN
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEECCCCEEEEEEEC
TGIKDPKDLEMRINNIPGVLENGLFVNLTDKVLVGKIENNVPVLFSPSKGS
CCCCCCCHHHEEECCCCCHHHCCEEEEEECCEEEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]