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The map label for this gene is entA [C]

Identifier: 123966757

GI number: 123966757

Start: 1356092

End: 1357021

Strand: Direct

Name: entA [C]

Synonym: P9515_15241

Alternate gene names: 123966757

Gene position: 1356092-1357021 (Clockwise)

Preceding gene: 123966756

Following gene: 123966762

Centisome position: 79.57

GC content: 33.87

Gene sequence:

>930_bases
ATGACTGCAACTAATCTTAAGAATAGAAATTCCAATTGGACCATATCAGATATTCCCAATCTAGATGGCAAAACAGTTTT
CATCACAGGAGCGAATAGTGGTCTTGGCTATTACACAGCTAAAGCTTTAGCAGAAAAAAATGCCCATGTTGTACTTGCTT
GCAGAACTTTAGAAAAGGCTAATTCAGCCTTACACAAATTGAAGTCACTTAATCCTGAAGGAAAATTCACCCCCATTGAA
TTAGACTTGGCAGATTTAAATAAAGTGAGTGAAATTGGATCAAAAATTTCAACTGAGTTTGAGAAGTTAGACTTGCTAAT
TAACAATGCAGGAATAATGCATCCACCGAAAACATTAAGTCCACAAGGTTTTGAAATACAATTTGCGGTGAATCATTTAG
CTCATATGCTTTTAACATTAAAATTTCTTCCTTTAATTGAAAAGCAAAAAGGATCTAGAATAGTAACAGTAACTTCTGGC
GCCCAGTTTTTTGGAAAAGTTGGATGGAATAATCTAAAAGCAGAAAATTACTACAACAAATGGGAATCATACGCTAACAG
TAAATTAGCTAATGTAATGTTTGCTTTAGAATTAAACGAAAAACTTGAGCAAAAACATATTCTATCTTTAGCAGCTCATC
CAGGTATTGCAAAAACAAATCTTTTTTCTGCCCAGAAACCAAAGCCTAATCCAATTGAAATTTTCTCTTTAGAATTATTT
AGCCCAATTTTTCAATCTGCCGAAATGGGTGCTTTACCACAATTATTTGCTGCTACTTCGCCTCAGGCAAAAGGGGGTGA
ACATTACGGGCCTAAATTTAATTTTAGAGGTCACCCAAAATTATCTCCAGCTTCACCATTTGCTACAAATAAGAAAGAAA
GAAAAAGTCTTTGGGAAAAGAGTATGGAAATACTTAGTAATTTTTTATGA

Upstream 100 bases:

>100_bases
TTTTAAGTGGTCACGATCCTTCTGATTAGTATTTACGATAAAAATAATAAATAAGATTAATTCTTAATTAAGTTTCAACA
ATCTAGATAAGTTTTCAAAA

Downstream 100 bases:

>100_bases
GTTTTTTAGTTTTATTAACTTCAAAAAATATTTCAAGATATGCAATTCACTTTCTGAAAGTTTCATAAATTCAATTAATG
CCTGATAATTTTCTTCATCA

Product: short-chain dehydrogenase/reductase

Products: protochlorophyllide; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTATNLKNRNSNWTISDIPNLDGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKANSALHKLKSLNPEGKFTPIE
LDLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLSPQGFEIQFAVNHLAHMLLTLKFLPLIEKQKGSRIVTVTSG
AQFFGKVGWNNLKAENYYNKWESYANSKLANVMFALELNEKLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELF
SPIFQSAEMGALPQLFAATSPQAKGGEHYGPKFNFRGHPKLSPASPFATNKKERKSLWEKSMEILSNFL

Sequences:

>Translated_309_residues
MTATNLKNRNSNWTISDIPNLDGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKANSALHKLKSLNPEGKFTPIE
LDLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLSPQGFEIQFAVNHLAHMLLTLKFLPLIEKQKGSRIVTVTSG
AQFFGKVGWNNLKAENYYNKWESYANSKLANVMFALELNEKLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELF
SPIFQSAEMGALPQLFAATSPQAKGGEHYGPKFNFRGHPKLSPASPFATNKKERKSLWEKSMEILSNFL
>Mature_308_residues
TATNLKNRNSNWTISDIPNLDGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKANSALHKLKSLNPEGKFTPIEL
DLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLSPQGFEIQFAVNHLAHMLLTLKFLPLIEKQKGSRIVTVTSGA
QFFGKVGWNNLKAENYYNKWESYANSKLANVMFALELNEKLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELFS
PIFQSAEMGALPQLFAATSPQAKGGEHYGPKFNFRGHPKLSPASPFATNKKERKSLWEKSMEILSNFL

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI186928839, Length=286, Percent_Identity=34.6153846153846, Blast_Score=155, Evalue=3e-38,
Organism=Homo sapiens, GI10190746, Length=308, Percent_Identity=35.3896103896104, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI225579078, Length=289, Percent_Identity=34.9480968858132, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI166795268, Length=307, Percent_Identity=30.9446254071661, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=29.4314381270903, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI146231950, Length=291, Percent_Identity=32.3024054982818, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI193804850, Length=289, Percent_Identity=29.757785467128, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI19923931, Length=255, Percent_Identity=32.5490196078431, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI13375997, Length=142, Percent_Identity=33.8028169014084, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI72534732, Length=142, Percent_Identity=33.8028169014084, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1786812, Length=204, Percent_Identity=27.9411764705882, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193207620, Length=304, Percent_Identity=28.9473684210526, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17532805, Length=314, Percent_Identity=28.343949044586, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17558006, Length=290, Percent_Identity=28.6206896551724, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17532791, Length=303, Percent_Identity=27.0627062706271, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI72001364, Length=294, Percent_Identity=29.2517006802721, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17505416, Length=211, Percent_Identity=32.7014218009479, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI71992402, Length=297, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17535059, Length=297, Percent_Identity=26.9360269360269, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32565532, Length=218, Percent_Identity=33.4862385321101, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533174, Length=296, Percent_Identity=26.3513513513513, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533172, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=210, Percent_Identity=29.0476190476191, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17558996, Length=214, Percent_Identity=28.0373831775701, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=322, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6322227, Length=263, Percent_Identity=23.574144486692, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45554248, Length=288, Percent_Identity=34.0277777777778, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24640117, Length=288, Percent_Identity=34.0277777777778, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24586328, Length=286, Percent_Identity=33.2167832167832, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28573296, Length=247, Percent_Identity=36.4372469635627, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI22024069, Length=283, Percent_Identity=34.2756183745583, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19921754, Length=281, Percent_Identity=34.8754448398576, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI161076371, Length=249, Percent_Identity=31.7269076305221, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129347, Length=255, Percent_Identity=30.1960784313725, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24656154, Length=249, Percent_Identity=33.7349397590361, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19922628, Length=249, Percent_Identity=33.7349397590361, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI45553409, Length=286, Percent_Identity=30.4195804195804, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647948, Length=286, Percent_Identity=30.4195804195804, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24647946, Length=286, Percent_Identity=30.4195804195804, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24647931, Length=310, Percent_Identity=27.4193548387097, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21358495, Length=207, Percent_Identity=27.536231884058, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.33

Molecular weight: Translated: 34223; Mature: 34092

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATNLKNRNSNWTISDIPNLDGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKA
CCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEHHHHHH
NSALHKLKSLNPEGKFTPIELDLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLS
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PQGFEIQFAVNHLAHMLLTLKFLPLIEKQKGSRIVTVTSGAQFFGKVGWNNLKAENYYNK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYANSKLANVMFALELNEKLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELF
HHHHHCCHHHHEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHH
SPIFQSAEMGALPQLFAATSPQAKGGEHYGPKFNFRGHPKLSPASPFATNKKERKSLWEK
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SMEILSNFL
HHHHHHHCC
>Mature Secondary Structure 
TATNLKNRNSNWTISDIPNLDGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKA
CCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEEEHHHHHH
NSALHKLKSLNPEGKFTPIELDLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLS
HHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PQGFEIQFAVNHLAHMLLTLKFLPLIEKQKGSRIVTVTSGAQFFGKVGWNNLKAENYYNK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHH
WESYANSKLANVMFALELNEKLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELF
HHHHHCCHHHHEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEHHHH
SPIFQSAEMGALPQLFAATSPQAKGGEHYGPKFNFRGHPKLSPASPFATNKKERKSLWEK
HHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SMEILSNFL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: chlorophyllide a; NADP+

Specific reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]