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The map label for this gene is prmA

Identifier: 123966747

GI number: 123966747

Start: 1347451

End: 1348353

Strand: Reverse

Name: prmA

Synonym: P9515_15141

Alternate gene names: 123966747

Gene position: 1348353-1347451 (Counterclockwise)

Preceding gene: 123966748

Following gene: 123966746

Centisome position: 79.12

GC content: 27.91

Gene sequence:

>903_bases
ATGGAAATAAATTATTGGTATAAACTCACCTTTGAAATAGAAGCTAATTTAGAAGAGATCATTATTTGGAAATTAAACGA
ATTAGGTATATCTAGTTATGCATTAGAAATTTTATTAAATAATAAAAATAATAAAAAAGTTTTAATTTGGCTTCCAAATT
TAAATTGGCCAAAAAGTTTAAGAATTAAACTTGAGAGAAATATTAAAGAGGTTTTAGATAAAAATAATTATCGAACTAAT
TGTTTTGAGTGGATTGTTATTGAGCAGGAAGATTGGATGTCAAGTTGGAAAAAGTATTGGGGACCAGAACTTGTAGGCAA
AAAATTACTTGTATTGCCTTGTTGGCTTGAATTGCCAGAGAAATTTAAAAATAAGAAAGTTATTAAAATAGATCCAGGAG
CAGCTTTTGGTACTGGCAGTCATCCCACGACATCTCTTTGCTTAGAAGAATTGGAAAAATTTTCATTATCGAATAAGAAA
ATATTAGATATAGGTTCAGGAAGCGGTATTTTAAGTATTGCTGCTAGATATTTTGGAGCTAGCAAGGTTTATTCTATTGA
TAATGATTATCTGGCAATCAATTCTACTGAATCTAATTTTCGGCTAAATTTTGGTGATTTAGATGATTTAAAGACATATC
TAGGAAGATTCGATGAGTTGGTTTCAAAATATTCTTTAAAGAATTTTGATTTGATTTTATGTAATATTCTTGCAGAAGTG
ATAAAAGGCATAATCCCTGATATTCGTAACTGTTTAAAAATAAATGGAGAAGTGATTTTTAGTGGAATTTTGAATTCTCA
AAAAGATGAAATTATTAAATTATTAAATGCTAGTAATTTACAAATAAATGATGTATCTTCTAAACAAGGCTGGGTGTGCA
TTACAGCACAAAAAATCATCTGA

Upstream 100 bases:

>100_bases
ATTGATGATCCGATCCCCACAAATTTGCTTGAATCGATTCTTGAAGTTGAGGGTATTACTAGTTCCGATCCAGTAACTTT
GTAAATACTCTAAGAGTTTA

Downstream 100 bases:

>100_bases
ACTGAAAACATATAAGTTTTCCTGATCTAACCCTCTTTTTACATTTCATTGTTTCATTTTTTACGCCAAAAACTCACAAA
TGGTTATGATCAATGTTAAA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MEINYWYKLTFEIEANLEEIIIWKLNELGISSYALEILLNNKNNKKVLIWLPNLNWPKSLRIKLERNIKEVLDKNNYRTN
CFEWIVIEQEDWMSSWKKYWGPELVGKKLLVLPCWLELPEKFKNKKVIKIDPGAAFGTGSHPTTSLCLEELEKFSLSNKK
ILDIGSGSGILSIAARYFGASKVYSIDNDYLAINSTESNFRLNFGDLDDLKTYLGRFDELVSKYSLKNFDLILCNILAEV
IKGIIPDIRNCLKINGEVIFSGILNSQKDEIIKLLNASNLQINDVSSKQGWVCITAQKII

Sequences:

>Translated_300_residues
MEINYWYKLTFEIEANLEEIIIWKLNELGISSYALEILLNNKNNKKVLIWLPNLNWPKSLRIKLERNIKEVLDKNNYRTN
CFEWIVIEQEDWMSSWKKYWGPELVGKKLLVLPCWLELPEKFKNKKVIKIDPGAAFGTGSHPTTSLCLEELEKFSLSNKK
ILDIGSGSGILSIAARYFGASKVYSIDNDYLAINSTESNFRLNFGDLDDLKTYLGRFDELVSKYSLKNFDLILCNILAEV
IKGIIPDIRNCLKINGEVIFSGILNSQKDEIIKLLNASNLQINDVSSKQGWVCITAQKII
>Mature_300_residues
MEINYWYKLTFEIEANLEEIIIWKLNELGISSYALEILLNNKNNKKVLIWLPNLNWPKSLRIKLERNIKEVLDKNNYRTN
CFEWIVIEQEDWMSSWKKYWGPELVGKKLLVLPCWLELPEKFKNKKVIKIDPGAAFGTGSHPTTSLCLEELEKFSLSNKK
ILDIGSGSGILSIAARYFGASKVYSIDNDYLAINSTESNFRLNFGDLDDLKTYLGRFDELVSKYSLKNFDLILCNILAEV
IKGIIPDIRNCLKINGEVIFSGILNSQKDEIIKLLNASNLQINDVSSKQGWVCITAQKII

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=212, Percent_Identity=33.9622641509434, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PROM5 (A2BY60)

Other databases:

- EMBL:   CP000552
- RefSeq:   YP_001011828.1
- ProteinModelPortal:   A2BY60
- SMR:   A2BY60
- STRING:   A2BY60
- GeneID:   4720078
- GenomeReviews:   CP000552_GR
- KEGG:   pmc:P9515_15141
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- ProtClustDB:   PRK00517
- BioCyc:   PMAR167542:P9515ORF_1582-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34478; Mature: 34478

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEINYWYKLTFEIEANLEEIIIWKLNELGISSYALEILLNNKNNKKVLIWLPNLNWPKSL
CCEEEEEEEEEEEECCCEEEEEEEECCCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHE
RIKLERNIKEVLDKNNYRTNCFEWIVIEQEDWMSSWKKYWGPELVGKKLLVLPCWLELPE
EEEEHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCHHHHCCEEEEEECHHHCHH
KFKNKKVIKIDPGAAFGTGSHPTTSLCLEELEKFSLSNKKILDIGSGSGILSIAARYFGA
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCC
SKVYSIDNDYLAINSTESNFRLNFGDLDDLKTYLGRFDELVSKYSLKNFDLILCNILAEV
CEEEEECCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IKGIIPDIRNCLKINGEVIFSGILNSQKDEIIKLLNASNLQINDVSSKQGWVCITAQKII
HHHHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MEINYWYKLTFEIEANLEEIIIWKLNELGISSYALEILLNNKNNKKVLIWLPNLNWPKSL
CCEEEEEEEEEEEECCCEEEEEEEECCCCCCEEEEEEEEECCCCCEEEEECCCCCCCHHE
RIKLERNIKEVLDKNNYRTNCFEWIVIEQEDWMSSWKKYWGPELVGKKLLVLPCWLELPE
EEEEHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCHHHHCCEEEEEECHHHCHH
KFKNKKVIKIDPGAAFGTGSHPTTSLCLEELEKFSLSNKKILDIGSGSGILSIAARYFGA
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCC
SKVYSIDNDYLAINSTESNFRLNFGDLDDLKTYLGRFDELVSKYSLKNFDLILCNILAEV
CEEEEECCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IKGIIPDIRNCLKINGEVIFSGILNSQKDEIIKLLNASNLQINDVSSKQGWVCITAQKII
HHHHHHHHHHHHCCCCEEEEEEHHCCCHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA