Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 123966675

GI number: 123966675

Start: 1276717

End: 1277628

Strand: Reverse

Name: era [H]

Synonym: P9515_14421

Alternate gene names: 123966675

Gene position: 1277628-1276717 (Counterclockwise)

Preceding gene: 123966677

Following gene: 123966674

Centisome position: 74.97

GC content: 30.59

Gene sequence:

>912_bases
TTGAATAATTATAAATCTGGTTTCGTAACTTTACTAGGAAGACCAAATGTTGGGAAATCAACCTTAATAAACAAGTTAAT
TGGAGAGAAAATAACTATTACTTCCCCTGTTGCTCAAACTACTAGAAATAGATTAAAAGGAATACTTACTACAGAATTTG
GACAAATAATTTTTGTAGATACACCTGGAGTCCATAAACCTCATCATCTTCTAGGTGAAATACTTGTAAAAAATGCCAAA
TCAGCAATAAAAGGTGTAGATATGGTTATTTTAGTTCTCGACTCAAGTGTTGAACCAGGGAGAGGCGATGAATACATAAA
AGATTTTTTAGTTTCAAATAAAACAGAATTTATTATTGTATTGAATAAATGGGATTTGGTGAATAAGGAATTCAAGAGTC
TTCGTTTAGATCAATATAGAAAAGTTTTTGGAACTAGTAAAAGTTTTCAAACTGTAAGTGCATCTGAAGGATACGGTTGC
TCTGAATTGATTAATATAATTTTAAATTTTCTCCCAAAAGGACCAATGTTATATGAGGAAGATACAATATGCGATCAACC
CTTAGATAATTTATTAGCGGATTTAATAAGAGAGCAGGTATTAATCAATACAAGAGAAGAAGTCCCTCATAGTGTTGCGG
TAAAAATTGAAAAAATTAAGGAAATTAATAGAGATAATGGTAAAAAATTTACAGCCATATTGGCTACGATCATTGTTGAG
AGAACAAGTCAAAAGGGAATTCTAATAGGAAAAAAGGGTTCTATGTTAAAGACCATTGGTCAGACTGCAAGATCAAATAT
GAAGAAATTAATAAATGGCTCAGTTCATCTGGAATTATTTGTCAAAGTAATACCAAATTGGAGAAAAAAAGAATCTAAAT
TAATGGAGTTCGGTTATGAGGTGGATTACTAA

Upstream 100 bases:

>100_bases
CTGATATGTTTATTGCCTGAGTAAAAGAAGCTTCTTTTAAGTTTATGGTTTTTTTTTTCATTTTTGAGCAGAATTTTATT
ATGGATCTTTTAAAAGTCTT

Downstream 100 bases:

>100_bases
ATGACTAATTTGAATTTTGAAGTAATTACTTTGTTCCCCAAAGCTTTTGAATTAATAAATAATTTAGGTGTAATAACAAG
AGCTTTAGAGAAAAAGTTAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MNNYKSGFVTLLGRPNVGKSTLINKLIGEKITITSPVAQTTRNRLKGILTTEFGQIIFVDTPGVHKPHHLLGEILVKNAK
SAIKGVDMVILVLDSSVEPGRGDEYIKDFLVSNKTEFIIVLNKWDLVNKEFKSLRLDQYRKVFGTSKSFQTVSASEGYGC
SELINIILNFLPKGPMLYEEDTICDQPLDNLLADLIREQVLINTREEVPHSVAVKIEKIKEINRDNGKKFTAILATIIVE
RTSQKGILIGKKGSMLKTIGQTARSNMKKLINGSVHLELFVKVIPNWRKKESKLMEFGYEVDY

Sequences:

>Translated_303_residues
MNNYKSGFVTLLGRPNVGKSTLINKLIGEKITITSPVAQTTRNRLKGILTTEFGQIIFVDTPGVHKPHHLLGEILVKNAK
SAIKGVDMVILVLDSSVEPGRGDEYIKDFLVSNKTEFIIVLNKWDLVNKEFKSLRLDQYRKVFGTSKSFQTVSASEGYGC
SELINIILNFLPKGPMLYEEDTICDQPLDNLLADLIREQVLINTREEVPHSVAVKIEKIKEINRDNGKKFTAILATIIVE
RTSQKGILIGKKGSMLKTIGQTARSNMKKLINGSVHLELFVKVIPNWRKKESKLMEFGYEVDY
>Mature_303_residues
MNNYKSGFVTLLGRPNVGKSTLINKLIGEKITITSPVAQTTRNRLKGILTTEFGQIIFVDTPGVHKPHHLLGEILVKNAK
SAIKGVDMVILVLDSSVEPGRGDEYIKDFLVSNKTEFIIVLNKWDLVNKEFKSLRLDQYRKVFGTSKSFQTVSASEGYGC
SELINIILNFLPKGPMLYEEDTICDQPLDNLLADLIREQVLINTREEVPHSVAVKIEKIKEINRDNGKKFTAILATIIVE
RTSQKGILIGKKGSMLKTIGQTARSNMKKLINGSVHLELFVKVIPNWRKKESKLMEFGYEVDY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=325, Percent_Identity=25.5384615384615, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=37.0748299319728, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082120, Length=165, Percent_Identity=28.4848484848485, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34077; Mature: 34077

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNYKSGFVTLLGRPNVGKSTLINKLIGEKITITSPVAQTTRNRLKGILTTEFGQIIFVD
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHEEECCCCEEEEE
TPGVHKPHHLLGEILVKNAKSAIKGVDMVILVLDSSVEPGRGDEYIKDFLVSNKTEFIIV
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEE
LNKWDLVNKEFKSLRLDQYRKVFGTSKSFQTVSASEGYGCSELINIILNFLPKGPMLYEE
EECCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEECC
DTICDQPLDNLLADLIREQVLINTREEVPHSVAVKIEKIKEINRDNGKKFTAILATIIVE
CCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RTSQKGILIGKKGSMLKTIGQTARSNMKKLINGSVHLELFVKVIPNWRKKESKLMEFGYE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHCCCC
VDY
CCC
>Mature Secondary Structure
MNNYKSGFVTLLGRPNVGKSTLINKLIGEKITITSPVAQTTRNRLKGILTTEFGQIIFVD
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHEEECCCCEEEEE
TPGVHKPHHLLGEILVKNAKSAIKGVDMVILVLDSSVEPGRGDEYIKDFLVSNKTEFIIV
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEE
LNKWDLVNKEFKSLRLDQYRKVFGTSKSFQTVSASEGYGCSELINIILNFLPKGPMLYEE
EECCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCEECC
DTICDQPLDNLLADLIREQVLINTREEVPHSVAVKIEKIKEINRDNGKKFTAILATIIVE
CCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RTSQKGILIGKKGSMLKTIGQTARSNMKKLINGSVHLELFVKVIPNWRKKESKLMEFGYE
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHEEHHHHHCCCHHHHHHHHHHCCCC
VDY
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA