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The map label for this gene is betA [C]

Identifier: 123966499

GI number: 123966499

Start: 1111964

End: 1113532

Strand: Direct

Name: betA [C]

Synonym: P9515_12661

Alternate gene names: 123966499

Gene position: 1111964-1113532 (Clockwise)

Preceding gene: 123966498

Following gene: 123966504

Centisome position: 65.25

GC content: 36.01

Gene sequence:

>1569_bases
ATGATAATAGATGATCATCACTATGACTTCATAATAATTGGAAGCGGTGCTGGTGGAGCCACTTTAGCCCGTCAATTATC
AAGAAAGGGGAAATGGGTCCTAGTTCTAGAGAGGGGAGGTCAGCTTCCTTTAGAAGAACAGAATATTATAGGCACGGATT
TATTTAGAAAAACAAGATATCACCCTGAGGGGGAAAATTGGCTTGGTCCTGATGGGGATCCTTTTGCTCCTCAAACTGTA
TATGCGCTTGGAGGGAACACTAAAATCTGGGGTGCAGTTTTAGAAAGGATGCGAACTGAAGATTTTGAAGATCTTTCTTT
ACAAGAGGGAACTTCTCCATCATGGCCCATATCATATGAGGAACTCGAACCATTTTATAGAAAAGCAGAAGAAATTTATA
ATGTAAAAGGGAGGCAAGGTATTGATAAAACAGAGCCTAATAGATCGAGTGGTTATGATAATCCCCCAAAATCTATAGAC
CCTTTATTCAAAGAGATACAAAATATTTTGATAGAAGAGGGATTTAATCCCTATTATCTACCAATTAGCTGGCCTGAAAG
TTCTCAAGATATTGATTTTGATAACTGTGCAATGTTTCAAAAAGGAGATGCCCAACTTTATGGAATTTATAATTCAAATC
AAGATTTCCTGAGAATTAAAACCAACGCTAAAGTTTTAAAACTAGATGTAAACTCTTCTGGGAAATCTGTCAAAGGTGTT
GAGGCAGAGATAGATGGGGATAAATGGCTTTTCTCCTCAGATATTGTTATTCTCTCAGCTGGAGCAATTAATACTCCTAT
AATTTTATTAAATTCAAAATCTTCATCACATCCAAATGGTTTAGCTAATAGTTCAAAAATGGTTGGCAAAAATTTGATGA
ATATTCAAATGACTTGTATTCTTCAAAGAGCTAATAATCTCACCAGTGGATATTTTTCAAAAACCTTAGGATTAAATGAT
TTTTACTTTGGGGATAAAAACGTTAATTTCCCATTAGGTCACATACAAACTGGAGGAGGAGTACTTAGGGATGCTTTTTT
TGCGGAATCTCCGCCAGTTCTATCTTTAATTACAAAATTAATACCCGACTTTGGATTAAAGAATTTAGCAAAAAGGTCAA
TATCATGGTGGGCAATGACGGAAGTCTTACCAGATCCTGAAAACGCAGTAACCATTCAAAATAATAAGGTAAAAATTAAT
TACATACATAACAATCTTGAGGCACACGATCGATTAGTTTATAGATGGCTTGACACTTTAAAAGTTATTGAGAATAACCC
CCTTTCTATATCAATAACCAGAACGCCGGCACACCCAAGAGGATTAGCTCCGCTAAGCATAGTTGGTTATTCCTGCGGGA
CTTGCAAGATGGGAAATGACCCGAAAACCTCAGTAGTTAATAAAAACGGGAAGTGTCATGACCTTGATAATCTTTATATT
TCAGATGCGAGTATATTTCCAAGCTGCCCAAGTATTGGGCATGGTTTAACAGTTATTGCTATGTCCCTCAAATTAGGAGA
TTATCTTACTTATGGAAATCTTTATAAACCATTAATATGCAGACCTTAA

Upstream 100 bases:

>100_bases
TTTGTTGATGTGATTTGGCTCCTTTTATTTGGTCTTATTTATTTGTGGCAATAAATTTAGTATTATTATTTCTAAATGAA
AATTATCAAATTTTCAAAAC

Downstream 100 bases:

>100_bases
GAATCTAATTAAGACTAATATTATCCGTAAATTATTAACTTATGATTTAAAAACTTTTCCTATATTTAAAATCAATAAAT
CATATGAAATAAATTTCGAA

Product: hypothetical protein

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: FAD Dependent Oxidoreductase; Choline Dehydrogenase; Dehydrogenase; Flavoprotein Related Choline Dehydrogenase; Dehydrogenase Subunit-Like Protein; GMC Oxidoreductase Family Protein; Oxidoreductase; GMC Oxidoreductase; GMC Oxidoreductase Family; Dehydrogenase Subunit; Glucose Dehydrogenase; 2-Keto-Gluconate Dehydrogenase; Gluconate 2-Dehydrogenase; Dehydrogenase Protein; Choline Dehydrogenase And Flavoproteins-Like Protein; Dehydrogenase-Like Protein; L-Sorbose Dehydrogenase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase GMC Family; Sugar-Alcohol Dehydrogenase; Glucase Dehydrogenase Subunit Alpha; Dehydrogenase Subunit I; Choline Dehydrogenase-Like Flavoprotein; GMC Family Oxidoreductase; Glucose-Methanol-Choline Family Oxidoreductase; Glucose Dehydrogenase Alpha Subunit; Oxidoreductase Chain; Gluconate Dehydrogenase; N-Terminal Membrane-Anchored Dehydrogenase; Oxidoreductase GMC Family Protein; Gluconate Dehydrogenase Subunit; Oxidoreductase-Like Protein; Dehydrogenase Transmembrane Protein

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MIIDDHHYDFIIIGSGAGGATLARQLSRKGKWVLVLERGGQLPLEEQNIIGTDLFRKTRYHPEGENWLGPDGDPFAPQTV
YALGGNTKIWGAVLERMRTEDFEDLSLQEGTSPSWPISYEELEPFYRKAEEIYNVKGRQGIDKTEPNRSSGYDNPPKSID
PLFKEIQNILIEEGFNPYYLPISWPESSQDIDFDNCAMFQKGDAQLYGIYNSNQDFLRIKTNAKVLKLDVNSSGKSVKGV
EAEIDGDKWLFSSDIVILSAGAINTPIILLNSKSSSHPNGLANSSKMVGKNLMNIQMTCILQRANNLTSGYFSKTLGLND
FYFGDKNVNFPLGHIQTGGGVLRDAFFAESPPVLSLITKLIPDFGLKNLAKRSISWWAMTEVLPDPENAVTIQNNKVKIN
YIHNNLEAHDRLVYRWLDTLKVIENNPLSISITRTPAHPRGLAPLSIVGYSCGTCKMGNDPKTSVVNKNGKCHDLDNLYI
SDASIFPSCPSIGHGLTVIAMSLKLGDYLTYGNLYKPLICRP

Sequences:

>Translated_522_residues
MIIDDHHYDFIIIGSGAGGATLARQLSRKGKWVLVLERGGQLPLEEQNIIGTDLFRKTRYHPEGENWLGPDGDPFAPQTV
YALGGNTKIWGAVLERMRTEDFEDLSLQEGTSPSWPISYEELEPFYRKAEEIYNVKGRQGIDKTEPNRSSGYDNPPKSID
PLFKEIQNILIEEGFNPYYLPISWPESSQDIDFDNCAMFQKGDAQLYGIYNSNQDFLRIKTNAKVLKLDVNSSGKSVKGV
EAEIDGDKWLFSSDIVILSAGAINTPIILLNSKSSSHPNGLANSSKMVGKNLMNIQMTCILQRANNLTSGYFSKTLGLND
FYFGDKNVNFPLGHIQTGGGVLRDAFFAESPPVLSLITKLIPDFGLKNLAKRSISWWAMTEVLPDPENAVTIQNNKVKIN
YIHNNLEAHDRLVYRWLDTLKVIENNPLSISITRTPAHPRGLAPLSIVGYSCGTCKMGNDPKTSVVNKNGKCHDLDNLYI
SDASIFPSCPSIGHGLTVIAMSLKLGDYLTYGNLYKPLICRP
>Mature_522_residues
MIIDDHHYDFIIIGSGAGGATLARQLSRKGKWVLVLERGGQLPLEEQNIIGTDLFRKTRYHPEGENWLGPDGDPFAPQTV
YALGGNTKIWGAVLERMRTEDFEDLSLQEGTSPSWPISYEELEPFYRKAEEIYNVKGRQGIDKTEPNRSSGYDNPPKSID
PLFKEIQNILIEEGFNPYYLPISWPESSQDIDFDNCAMFQKGDAQLYGIYNSNQDFLRIKTNAKVLKLDVNSSGKSVKGV
EAEIDGDKWLFSSDIVILSAGAINTPIILLNSKSSSHPNGLANSSKMVGKNLMNIQMTCILQRANNLTSGYFSKTLGLND
FYFGDKNVNFPLGHIQTGGGVLRDAFFAESPPVLSLITKLIPDFGLKNLAKRSISWWAMTEVLPDPENAVTIQNNKVKIN
YIHNNLEAHDRLVYRWLDTLKVIENNPLSISITRTPAHPRGLAPLSIVGYSCGTCKMGNDPKTSVVNKNGKCHDLDNLYI
SDASIFPSCPSIGHGLTVIAMSLKLGDYLTYGNLYKPLICRP

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 58059; Mature: 58059

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDDHHYDFIIIGSGAGGATLARQLSRKGKWVLVLERGGQLPLEEQNIIGTDLFRKTRY
CEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCC
HPEGENWLGPDGDPFAPQTVYALGGNTKIWGAVLERMRTEDFEDLSLQEGTSPSWPISYE
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
ELEPFYRKAEEIYNVKGRQGIDKTEPNRSSGYDNPPKSIDPLFKEIQNILIEEGFNPYYL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
PISWPESSQDIDFDNCAMFQKGDAQLYGIYNSNQDFLRIKTNAKVLKLDVNSSGKSVKGV
EEECCCCCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCEEEEEEECCCCCCCCCE
EAEIDGDKWLFSSDIVILSAGAINTPIILLNSKSSSHPNGLANSSKMVGKNLMNIQMTCI
EEEECCCEEEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHCHHHEEEEEEE
LQRANNLTSGYFSKTLGLNDFYFGDKNVNFPLGHIQTGGGVLRDAFFAESPPVLSLITKL
EEHHCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCHHHHHHHH
IPDFGLKNLAKRSISWWAMTEVLPDPENAVTIQNNKVKINYIHNNLEAHDRLVYRWLDTL
HCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEECCEEEEEEEECCCCHHHHHHHHHHHHH
KVIENNPLSISITRTPAHPRGLAPLSIVGYSCGTCKMGNDPKTSVVNKNGKCHDLDNLYI
HHHCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCEEECCCEEE
SDASIFPSCPSIGHGLTVIAMSLKLGDYLTYGNLYKPLICRP
ECCCCCCCCCCCCCCCEEEEEEHHHCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MIIDDHHYDFIIIGSGAGGATLARQLSRKGKWVLVLERGGQLPLEEQNIIGTDLFRKTRY
CEECCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHCC
HPEGENWLGPDGDPFAPQTVYALGGNTKIWGAVLERMRTEDFEDLSLQEGTSPSWPISYE
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
ELEPFYRKAEEIYNVKGRQGIDKTEPNRSSGYDNPPKSIDPLFKEIQNILIEEGFNPYYL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEE
PISWPESSQDIDFDNCAMFQKGDAQLYGIYNSNQDFLRIKTNAKVLKLDVNSSGKSVKGV
EEECCCCCCCCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCEEEEEEECCCCCCCCCE
EAEIDGDKWLFSSDIVILSAGAINTPIILLNSKSSSHPNGLANSSKMVGKNLMNIQMTCI
EEEECCCEEEEECCEEEEECCCCCCCEEEEECCCCCCCCCCCCCHHHHHCHHHEEEEEEE
LQRANNLTSGYFSKTLGLNDFYFGDKNVNFPLGHIQTGGGVLRDAFFAESPPVLSLITKL
EEHHCCCCCCHHHHHCCCCEEEECCCCCCCCCCEEECCCCHHHHHHHCCCCCHHHHHHHH
IPDFGLKNLAKRSISWWAMTEVLPDPENAVTIQNNKVKINYIHNNLEAHDRLVYRWLDTL
HCCCCHHHHHHHCCCEEEEECCCCCCCCEEEEECCEEEEEEEECCCCHHHHHHHHHHHHH
KVIENNPLSISITRTPAHPRGLAPLSIVGYSCGTCKMGNDPKTSVVNKNGKCHDLDNLYI
HHHCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCCCCCEECCCCCEEECCCEEE
SDASIFPSCPSIGHGLTVIAMSLKLGDYLTYGNLYKPLICRP
ECCCCCCCCCCCCCCCEEEEEEHHHCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA