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The map label for this gene is crtH [H]

Identifier: 123966439

GI number: 123966439

Start: 1063070

End: 1064614

Strand: Reverse

Name: crtH [H]

Synonym: P9515_12061

Alternate gene names: 123966439

Gene position: 1064614-1063070 (Counterclockwise)

Preceding gene: 123966440

Following gene: 123966438

Centisome position: 62.47

GC content: 33.01

Gene sequence:

>1545_bases
ATGCAATCTTATAAAGAAAGTTTTGATGCAATTATTATTGGCTCTGGAATAGGGGGATTGGTAACTGCCTCACAATTAGC
GTCCAAAGGTGCGAAAGTTCTAGTGCTTGAAAAATATATTATTCCTGGAGGTAGCGGAGGATCATTTAAGAGAAAAGGCT
ATACCTTTGATGTAGGAGCATCTATGATTTTTGGTTTTGGGGAGACTGGATATACCAATTTGCTAACTCGCGCTTTAAAG
GATGTAAATGAAAAATGTGAAACAATCCCTGATCCTGTCCAACTCGAATATCATCTTCCTGATGGATTCAGTATTTCTGT
AGATAAAAGTTACGAGAAATTTATAAGTAAATTGTCTGAACGTTTTCCACATGAGAAGGAGGGAATTAAAAAATTTTATA
AAACTTGTTCAAATGTTTTCAATTGTTTAGATTCAATGCCGCTTTTATCAATTGAAGACCCTAGTTATCTTTTTAAGGTT
TTCTTTAAGGCGCCACTATCTTGTTTAGGTTTAGCGAGATGGCTACCAATAAATGCTGGCGATGTTGCAAGAAGGTTTAT
TAATGATCCTGAACTTTTGAAATTTATTGATATTGAATGTTTTTGTTGGTCAGTAATGCCTGCTATTAAAACTCCAATGA
TCAATGCAGGTATGGTTTTTACCGATAGACATGCCGGCGGTATTAATTATCCAAAAGGGGGAGTAGGCAAGATTGCAGAG
AAATTAGTTTCAGGATTGGAAAAATTAGGCAGTAAAATTCGGTATAGAGCTAATGTTGTTGAAATACTTTTAAAAGATAA
AAAAGCGATAGGAGTAAAACTATCAAATGGAGAAGAAATCTACTCAAATATTATCGTGTCTAACTCTACAAGATGGGACA
CTTTTGGACTTGATAATCAAAAAAAAGGACTAATTAAAAGTGATTCGGTTCCAAAAAATGAACATAAATGGTCAGAAACT
TATAAACCTTCGCCATCTTTTGTTTCAATTCACCTTGGTGTTAATCAAGATTTAATAGATAAAGATTTTAATTGTCATCA
TATTATTGTTGAAAATTGGAATGAATTAGAAAATGAAAAAGGGGTGATTTTTATTTCTATTCCAACCTTACTAGATCCAT
CTTTAGCGCCAAAAGGTAAACATATTATCCATACCTTTACACCTTCATCAATCGATGAATGGGAGAACCTATCAAGAAAA
GACTATATCAAGAAAAAGGAACTATATTATAATTTTATGATTGAAAAAATTTCTAAATTAATTCCTAACTTAGATCAAAA
TATTGATCATAAAGAAATTGGCACTCCAAGAACTCATAAGAAATTCCTTGGAAGATTCGAAGGTAGTTATGGACCAATTC
CTAATAAAAAATTATTGGGACTACTCCCCATGCCATTCAATACTACAAAAATTAGAAACCTCTATTGCGTCGGCGATTCA
TGTTTCCCCGGACAAGGTCTGAATGCAGTAGCGTTTAGTGGTTATGCTTGCGCTCACAAAATAGGATCTAAATTAAATAT
AAATAGTTTTAATTTGCCAGACTAA

Upstream 100 bases:

>100_bases
AGAAGTATTAAAAGAATTTAAAAAAGTATTAGATTCATCTTTTGAAAAAGATCACATACTTGTTTAGATAACTTAAAATG
AATTATTAAAAAAATTAAAA

Downstream 100 bases:

>100_bases
CCAGTTTCAATAATTTCAATAAGATGACAGAAAAATTTAAAACTCTTTTTTTTGTTAGAAGTTCTCTTATTACATTATAT
TTTGCTCTTACGATTCCTAT

Product: putative carotenoid isomerase

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MQSYKESFDAIIIGSGIGGLVTASQLASKGAKVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGETGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPDGFSISVDKSYEKFISKLSERFPHEKEGIKKFYKTCSNVFNCLDSMPLLSIEDPSYLFKV
FFKAPLSCLGLARWLPINAGDVARRFINDPELLKFIDIECFCWSVMPAIKTPMINAGMVFTDRHAGGINYPKGGVGKIAE
KLVSGLEKLGSKIRYRANVVEILLKDKKAIGVKLSNGEEIYSNIIVSNSTRWDTFGLDNQKKGLIKSDSVPKNEHKWSET
YKPSPSFVSIHLGVNQDLIDKDFNCHHIIVENWNELENEKGVIFISIPTLLDPSLAPKGKHIIHTFTPSSIDEWENLSRK
DYIKKKELYYNFMIEKISKLIPNLDQNIDHKEIGTPRTHKKFLGRFEGSYGPIPNKKLLGLLPMPFNTTKIRNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGSKLNINSFNLPD

Sequences:

>Translated_514_residues
MQSYKESFDAIIIGSGIGGLVTASQLASKGAKVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGETGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPDGFSISVDKSYEKFISKLSERFPHEKEGIKKFYKTCSNVFNCLDSMPLLSIEDPSYLFKV
FFKAPLSCLGLARWLPINAGDVARRFINDPELLKFIDIECFCWSVMPAIKTPMINAGMVFTDRHAGGINYPKGGVGKIAE
KLVSGLEKLGSKIRYRANVVEILLKDKKAIGVKLSNGEEIYSNIIVSNSTRWDTFGLDNQKKGLIKSDSVPKNEHKWSET
YKPSPSFVSIHLGVNQDLIDKDFNCHHIIVENWNELENEKGVIFISIPTLLDPSLAPKGKHIIHTFTPSSIDEWENLSRK
DYIKKKELYYNFMIEKISKLIPNLDQNIDHKEIGTPRTHKKFLGRFEGSYGPIPNKKLLGLLPMPFNTTKIRNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGSKLNINSFNLPD
>Mature_514_residues
MQSYKESFDAIIIGSGIGGLVTASQLASKGAKVLVLEKYIIPGGSGGSFKRKGYTFDVGASMIFGFGETGYTNLLTRALK
DVNEKCETIPDPVQLEYHLPDGFSISVDKSYEKFISKLSERFPHEKEGIKKFYKTCSNVFNCLDSMPLLSIEDPSYLFKV
FFKAPLSCLGLARWLPINAGDVARRFINDPELLKFIDIECFCWSVMPAIKTPMINAGMVFTDRHAGGINYPKGGVGKIAE
KLVSGLEKLGSKIRYRANVVEILLKDKKAIGVKLSNGEEIYSNIIVSNSTRWDTFGLDNQKKGLIKSDSVPKNEHKWSET
YKPSPSFVSIHLGVNQDLIDKDFNCHHIIVENWNELENEKGVIFISIPTLLDPSLAPKGKHIIHTFTPSSIDEWENLSRK
DYIKKKELYYNFMIEKISKLIPNLDQNIDHKEIGTPRTHKKFLGRFEGSYGPIPNKKLLGLLPMPFNTTKIRNLYCVGDS
CFPGQGLNAVAFSGYACAHKIGSKLNINSFNLPD

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=525, Percent_Identity=24, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540238, Length=557, Percent_Identity=23.1597845601436, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 57464; Mature: 57464

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSYKESFDAIIIGSGIGGLVTASQLASKGAKVLVLEKYIIPGGSGGSFKRKGYTFDVGA
CCCHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCEEEECCC
SMIFGFGETGYTNLLTRALKDVNEKCETIPDPVQLEYHLPDGFSISVDKSYEKFISKLSE
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHH
RFPHEKEGIKKFYKTCSNVFNCLDSMPLLSIEDPSYLFKVFFKAPLSCLGLARWLPINAG
HCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCHHHHHHHHHCCCCHH
DVARRFINDPELLKFIDIECFCWSVMPAIKTPMINAGMVFTDRHAGGINYPKGGVGKIAE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
KLVSGLEKLGSKIRYRANVVEILLKDKKAIGVKLSNGEEIYSNIIVSNSTRWDTFGLDNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHEECCCCCCCCCCCCCC
KKGLIKSDSVPKNEHKWSETYKPSPSFVSIHLGVNQDLIDKDFNCHHIIVENWNELENEK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCEEEECCCHHHCCCC
GVIFISIPTLLDPSLAPKGKHIIHTFTPSSIDEWENLSRKDYIKKKELYYNFMIEKISKL
CEEEEEEHHHCCCCCCCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IPNLDQNIDHKEIGTPRTHKKFLGRFEGSYGPIPNKKLLGLLPMPFNTTKIRNLYCVGDS
CCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCC
CFPGQGLNAVAFSGYACAHKIGSKLNINSFNLPD
CCCCCCCCEEEECCHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MQSYKESFDAIIIGSGIGGLVTASQLASKGAKVLVLEKYIIPGGSGGSFKRKGYTFDVGA
CCCHHCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCEEEECCC
SMIFGFGETGYTNLLTRALKDVNEKCETIPDPVQLEYHLPDGFSISVDKSYEKFISKLSE
CEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHH
RFPHEKEGIKKFYKTCSNVFNCLDSMPLLSIEDPSYLFKVFFKAPLSCLGLARWLPINAG
HCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCHHHHHHHHHCCCCHH
DVARRFINDPELLKFIDIECFCWSVMPAIKTPMINAGMVFTDRHAGGINYPKGGVGKIAE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHHHHH
KLVSGLEKLGSKIRYRANVVEILLKDKKAIGVKLSNGEEIYSNIIVSNSTRWDTFGLDNQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHEECCCCCCCCCCCCCC
KKGLIKSDSVPKNEHKWSETYKPSPSFVSIHLGVNQDLIDKDFNCHHIIVENWNELENEK
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHCCCCCCCEEEECCCHHHCCCC
GVIFISIPTLLDPSLAPKGKHIIHTFTPSSIDEWENLSRKDYIKKKELYYNFMIEKISKL
CEEEEEEHHHCCCCCCCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IPNLDQNIDHKEIGTPRTHKKFLGRFEGSYGPIPNKKLLGLLPMPFNTTKIRNLYCVGDS
CCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCC
CFPGQGLNAVAFSGYACAHKIGSKLNINSFNLPD
CCCCCCCCEEEECCHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592436 [H]