Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 123966426

GI number: 123966426

Start: 1049435

End: 1051126

Strand: Reverse

Name: recD [H]

Synonym: P9515_11931

Alternate gene names: 123966426

Gene position: 1051126-1049435 (Counterclockwise)

Preceding gene: 123966427

Following gene: 123966425

Centisome position: 61.68

GC content: 22.99

Gene sequence:

>1692_bases
ATGAATTATAAAAAACAAGATATTGAAGAATTTGAATATATTCATATCTTTAATCTTCTAAAGGATATACTTAAATTTAA
TGAAAAAAAATATGGAGATTATGTTAAGGACACATTAAAAATATTATTAGAACTTGAGAAAAATGGTGAAACCATAATAG
ACGTAGATAAGACTGTAGTAGGTTTTGAATTATTAAAAGATGGATGGCCTAATATTCATTTAAAAGTTCTTAAGGATATA
GGATTATTAAATTCAGTTAATTCCCCATTCGTATTTAATAATAGAAAATTAACATTAGTAAAATGGTCTCGGAAAATAAA
AAGAGTTCTTAATGCCTTCTTAAAAAAAATAGACAAAATTGCAATAAATTCGAATAATGATAATAAGCTTGATCAAATAA
AAAATATTTTTAAAAGTTCAAATTTGGTTTTTTTGCAAGGAGGACCCGGTACAGGCAAAACAACTATGATTATAAATTTT
ATACTCTATTGCTTGAAAAGTGATACTTATTTAAACATAGGACTTGCCGCACCTACAGGTAAAGCAACATCTCGACTTAA
AGAATCTCTTAATCAACAAAAAGATATCCTTTTAAGTAATAGTCTTGATCAAATAGAATGTCAAACTTTACATAAATGGA
TTTTCAATTCTAATAATAAAGCTATTGAATTTAAATTTAAATTAAAGGAACTAGATATTTTCATAATTGATGAAATGTCA
ATGGTAAATATTGATATAATCGAAACAATTTTAGATTTAATAGCTAAAGATTGCAAAATCATTCTTGTTGGAGATAGAAA
TCAATTATCTCCAGTTAAAAATTGTTCTATATGGAATTATTTATTTGAATATTCTGATAATAAATTAATAAATTCTTGTA
TAGTTAATCTAAAAAAAACTTATAGAAATAGTGGGGATATTTCATTACTTAGTAATCTTGTATTTAATAATAATAATTCT
TTATTTAATAAAAAGATCAATGAATTAGAAAAAGAAAAAAAAATCAAAGAAATAAATATTTTAAAAAGTAATAATACAAA
TATTCCTATAGAGCTTTTGAATATTATCAAAAATAATCTTTCAAAATTAAGAAAATCAACATCAAATTTAAGTAATAAAA
AATATATTTTTGATAATAATATTGATAACTTAATATCCCATGAAAAAGATTTAGTTAATAAAATTTTATTTGATTTACAA
AGTCATTTGATTTTATGCGAAAAGAATACAGGAAATTGGAGTGTTGAAGATATAAACGATACCGTTATTGGAAAAACAAA
ACCTTATGATTTTAAAAATCTTGAAGAAGGTTTACCAATTATGTGTACTAAAAATAATTATGAGCTTGGCATATCAAATG
GAGATATTGGAGTTTTAATTGGAAATAATGATAATAGGAAATACCTTTTTAGGAAGTTTAATGATAATAATGAGCTTGTT
GTTCAGTTAATAGACCCATCAAATTTAGAAAATATAGTTCCAGCAATTGCAATTACAATTCATAAATCCCAAGGGAGTGA
ATCTGAGAAAGTAAGTATTTTATGGCTTAAAAAAACTAAATTAGATGAATCCATAAATAGCGATAAAAAAGAAAGTGAAA
ATATATTCTTCAGGGATAATTATGAGAAAAGATTGCTTTATACAGCAATAACTAGAGCCAAGAAACTTTTAGATATTTAT
TATTTAAATTAA

Upstream 100 bases:

>100_bases
TCAATTTATTTGAAAAATCTGTTGAGACAGATAACACTCCAGGTCTTTTTATAAGCCAAGCTCCTATTAATAGGATTAGT
TATCTGGATAATATTTTTAA

Downstream 100 bases:

>100_bases
AACTGAATTACTAGCAAATAGCAGGATTTCAACCTCTAGATGCTAGATTAGAAACTCGGCTCTGAAAGGCTAATCAACAA
TTTAAGATTTTTAGATAAAT

Product: exodeoxyribonuclease V 67 kD polypeptide

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MNYKKQDIEEFEYIHIFNLLKDILKFNEKKYGDYVKDTLKILLELEKNGETIIDVDKTVVGFELLKDGWPNIHLKVLKDI
GLLNSVNSPFVFNNRKLTLVKWSRKIKRVLNAFLKKIDKIAINSNNDNKLDQIKNIFKSSNLVFLQGGPGTGKTTMIINF
ILYCLKSDTYLNIGLAAPTGKATSRLKESLNQQKDILLSNSLDQIECQTLHKWIFNSNNKAIEFKFKLKELDIFIIDEMS
MVNIDIIETILDLIAKDCKIILVGDRNQLSPVKNCSIWNYLFEYSDNKLINSCIVNLKKTYRNSGDISLLSNLVFNNNNS
LFNKKINELEKEKKIKEINILKSNNTNIPIELLNIIKNNLSKLRKSTSNLSNKKYIFDNNIDNLISHEKDLVNKILFDLQ
SHLILCEKNTGNWSVEDINDTVIGKTKPYDFKNLEEGLPIMCTKNNYELGISNGDIGVLIGNNDNRKYLFRKFNDNNELV
VQLIDPSNLENIVPAIAITIHKSQGSESEKVSILWLKKTKLDESINSDKKESENIFFRDNYEKRLLYTAITRAKKLLDIY
YLN

Sequences:

>Translated_563_residues
MNYKKQDIEEFEYIHIFNLLKDILKFNEKKYGDYVKDTLKILLELEKNGETIIDVDKTVVGFELLKDGWPNIHLKVLKDI
GLLNSVNSPFVFNNRKLTLVKWSRKIKRVLNAFLKKIDKIAINSNNDNKLDQIKNIFKSSNLVFLQGGPGTGKTTMIINF
ILYCLKSDTYLNIGLAAPTGKATSRLKESLNQQKDILLSNSLDQIECQTLHKWIFNSNNKAIEFKFKLKELDIFIIDEMS
MVNIDIIETILDLIAKDCKIILVGDRNQLSPVKNCSIWNYLFEYSDNKLINSCIVNLKKTYRNSGDISLLSNLVFNNNNS
LFNKKINELEKEKKIKEINILKSNNTNIPIELLNIIKNNLSKLRKSTSNLSNKKYIFDNNIDNLISHEKDLVNKILFDLQ
SHLILCEKNTGNWSVEDINDTVIGKTKPYDFKNLEEGLPIMCTKNNYELGISNGDIGVLIGNNDNRKYLFRKFNDNNELV
VQLIDPSNLENIVPAIAITIHKSQGSESEKVSILWLKKTKLDESINSDKKESENIFFRDNYEKRLLYTAITRAKKLLDIY
YLN
>Mature_563_residues
MNYKKQDIEEFEYIHIFNLLKDILKFNEKKYGDYVKDTLKILLELEKNGETIIDVDKTVVGFELLKDGWPNIHLKVLKDI
GLLNSVNSPFVFNNRKLTLVKWSRKIKRVLNAFLKKIDKIAINSNNDNKLDQIKNIFKSSNLVFLQGGPGTGKTTMIINF
ILYCLKSDTYLNIGLAAPTGKATSRLKESLNQQKDILLSNSLDQIECQTLHKWIFNSNNKAIEFKFKLKELDIFIIDEMS
MVNIDIIETILDLIAKDCKIILVGDRNQLSPVKNCSIWNYLFEYSDNKLINSCIVNLKKTYRNSGDISLLSNLVFNNNNS
LFNKKINELEKEKKIKEINILKSNNTNIPIELLNIIKNNLSKLRKSTSNLSNKKYIFDNNIDNLISHEKDLVNKILFDLQ
SHLILCEKNTGNWSVEDINDTVIGKTKPYDFKNLEEGLPIMCTKNNYELGISNGDIGVLIGNNDNRKYLFRKFNDNNELV
VQLIDPSNLENIVPAIAITIHKSQGSESEKVSILWLKKTKLDESINSDKKESENIFFRDNYEKRLLYTAITRAKKLLDIY
YLN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=417, Percent_Identity=23.021582733813, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 65016; Mature: 65016

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKKQDIEEFEYIHIFNLLKDILKFNEKKYGDYVKDTLKILLELEKNGETIIDVDKTVV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
GFELLKDGWPNIHLKVLKDIGLLNSVNSPFVFNNRKLTLVKWSRKIKRVLNAFLKKIDKI
HHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHEE
AINSNNDNKLDQIKNIFKSSNLVFLQGGPGTGKTTMIINFILYCLKSDTYLNIGLAAPTG
EECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
KATSRLKESLNQQKDILLSNSLDQIECQTLHKWIFNSNNKAIEFKFKLKELDIFIIDEMS
HHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCC
MVNIDIIETILDLIAKDCKIILVGDRNQLSPVKNCSIWNYLFEYSDNKLINSCIVNLKKT
EEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
YRNSGDISLLSNLVFNNNNSLFNKKINELEKEKKIKEINILKSNNTNIPIELLNIIKNNL
HCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
SKLRKSTSNLSNKKYIFDNNIDNLISHEKDLVNKILFDLQSHLILCEKNTGNWSVEDIND
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCC
TVIGKTKPYDFKNLEEGLPIMCTKNNYELGISNGDIGVLIGNNDNRKYLFRKFNDNNELV
CCCCCCCCCCCCHHHCCCCEEEECCCEEEEECCCCEEEEEECCCCCEEEEEEECCCCEEE
VQLIDPSNLENIVPAIAITIHKSQGSESEKVSILWLKKTKLDESINSDKKESENIFFRDN
EEEECCCCCHHHCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHCCCCCCCCCCEEEECC
YEKRLLYTAITRAKKLLDIYYLN
CHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MNYKKQDIEEFEYIHIFNLLKDILKFNEKKYGDYVKDTLKILLELEKNGETIIDVDKTVV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
GFELLKDGWPNIHLKVLKDIGLLNSVNSPFVFNNRKLTLVKWSRKIKRVLNAFLKKIDKI
HHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEECCCEEEEEHHHHHHHHHHHHHHHHHHEE
AINSNNDNKLDQIKNIFKSSNLVFLQGGPGTGKTTMIINFILYCLKSDTYLNIGLAAPTG
EECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCC
KATSRLKESLNQQKDILLSNSLDQIECQTLHKWIFNSNNKAIEFKFKLKELDIFIIDEMS
HHHHHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCC
MVNIDIIETILDLIAKDCKIILVGDRNQLSPVKNCSIWNYLFEYSDNKLINSCIVNLKKT
EEHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
YRNSGDISLLSNLVFNNNNSLFNKKINELEKEKKIKEINILKSNNTNIPIELLNIIKNNL
HCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
SKLRKSTSNLSNKKYIFDNNIDNLISHEKDLVNKILFDLQSHLILCEKNTGNWSVEDIND
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCC
TVIGKTKPYDFKNLEEGLPIMCTKNNYELGISNGDIGVLIGNNDNRKYLFRKFNDNNELV
CCCCCCCCCCCCHHHCCCCEEEECCCEEEEECCCCEEEEEECCCCCEEEEEEECCCCEEE
VQLIDPSNLENIVPAIAITIHKSQGSESEKVSILWLKKTKLDESINSDKKESENIFFRDN
EEEECCCCCHHHCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHCCCCCCCCCCEEEECC
YEKRLLYTAITRAKKLLDIYYLN
CHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]