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The map label for this gene is ruvA [H]

Identifier: 123966258

GI number: 123966258

Start: 916597

End: 917283

Strand: Direct

Name: ruvA [H]

Synonym: P9515_10251

Alternate gene names: 123966258

Gene position: 916597-917283 (Clockwise)

Preceding gene: 123966257

Following gene: 123966259

Centisome position: 53.79

GC content: 23.58

Gene sequence:

>687_bases
TTGATTAGTTGGGTAAAGGGAAAATTAGTAAGTTCATGGCAAACTAATAATAAATTTTATATTCTAATAAATTGTCAGGG
ATTAGGCTACGAAATTCAGACAATAGAATCTGTTTTTAATGAATTAAATTCAAAAAATGTTTCTGATAAAGAAATTATAC
TTTGGTTAAAACACATCAAAAAAGAAGATTCTGATTCACTTTTTGGCTTTTTCACTAAGGATCAAAGAGATTTTTTTATT
CAAATCCTAAATATTAAAGGTATTGGATCTCAAATAGGAATTGCATTATTAAATAAATTTACTTTAAATCAAATAATTAA
TGCAATATCAAATAATGACAAGAAATTGATAAGTTCTGTTCAAGGAATTGGACAAAAAATGACAGATCGAATAATACTTG
AATTGAAAAGTAAAGTATTTACTCAACAAATTGAAAAAGAAAATTTAAAAACAAATAATTTTCTTGAAGAGAATAAAGAA
TTAAATTCAATTTTTGAAGATCTTGAGCTAACACTTCAATCTCTAAATTACCCAAATAAAAAAATTAAAAACTTGTTCCC
TAAACTCATTAATGATATTAAAGATAATAAAATAGCGACATTAGAAATAAATTCCATTTCGTTTGAAAGCTTACTAAAAG
AAGCAATGAACTATTTAGACAAAAATAGTAGTAATTTAGGCCAATAA

Upstream 100 bases:

>100_bases
ATTAGCTCTCTCTTCATCTAGGGGCAAAGACAGATTTTGGGCTGTTCCAGCAGGTGGAACCGCCGGTGCTCTTATCGGAT
GTCAGGTGGATGGTGGTTAA

Downstream 100 bases:

>100_bases
CGTAGTAAAGTGGTAATAAGTAGATAAATTTAATGACTCTAGATACAGCTGAAAAACAAAAACTAATTGAATCTCATCAA
GTACATCCAACAGATACTGG

Product: putative holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MISWVKGKLVSSWQTNNKFYILINCQGLGYEIQTIESVFNELNSKNVSDKEIILWLKHIKKEDSDSLFGFFTKDQRDFFI
QILNIKGIGSQIGIALLNKFTLNQIINAISNNDKKLISSVQGIGQKMTDRIILELKSKVFTQQIEKENLKTNNFLEENKE
LNSIFEDLELTLQSLNYPNKKIKNLFPKLINDIKDNKIATLEINSISFESLLKEAMNYLDKNSSNLGQ

Sequences:

>Translated_228_residues
MISWVKGKLVSSWQTNNKFYILINCQGLGYEIQTIESVFNELNSKNVSDKEIILWLKHIKKEDSDSLFGFFTKDQRDFFI
QILNIKGIGSQIGIALLNKFTLNQIINAISNNDKKLISSVQGIGQKMTDRIILELKSKVFTQQIEKENLKTNNFLEENKE
LNSIFEDLELTLQSLNYPNKKIKNLFPKLINDIKDNKIATLEINSISFESLLKEAMNYLDKNSSNLGQ
>Mature_228_residues
MISWVKGKLVSSWQTNNKFYILINCQGLGYEIQTIESVFNELNSKNVSDKEIILWLKHIKKEDSDSLFGFFTKDQRDFFI
QILNIKGIGSQIGIALLNKFTLNQIINAISNNDKKLISSVQGIGQKMTDRIILELKSKVFTQQIEKENLKTNNFLEENKE
LNSIFEDLELTLQSLNYPNKKIKNLFPKLINDIKDNKIATLEINSISFESLLKEAMNYLDKNSSNLGQ

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=138, Percent_Identity=26.8115942028986, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 26260; Mature: 26260

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISWVKGKLVSSWQTNNKFYILINCQGLGYEIQTIESVFNELNSKNVSDKEIILWLKHIK
CCCCCCCHHHHCEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
KEDSDSLFGFFTKDQRDFFIQILNIKGIGSQIGIALLNKFTLNQIINAISNNDKKLISSV
CCCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QGIGQKMTDRIILELKSKVFTQQIEKENLKTNNFLEENKELNSIFEDLELTLQSLNYPNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIKNLFPKLINDIKDNKIATLEINSISFESLLKEAMNYLDKNSSNLGQ
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISWVKGKLVSSWQTNNKFYILINCQGLGYEIQTIESVFNELNSKNVSDKEIILWLKHIK
CCCCCCCHHHHCEECCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHC
KEDSDSLFGFFTKDQRDFFIQILNIKGIGSQIGIALLNKFTLNQIINAISNNDKKLISSV
CCCCCCEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QGIGQKMTDRIILELKSKVFTQQIEKENLKTNNFLEENKELNSIFEDLELTLQSLNYPNK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIKNLFPKLINDIKDNKIATLEINSISFESLLKEAMNYLDKNSSNLGQ
HHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]